| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.344421 |
| PM20D1 | peptidase M20 domain containing 1 | 0.134392 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.133388 |
| MCL1 | myeloid cell leukemia 1 | 0.113223 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.101959 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0900321 |
| FMNL2 | formin-like 2 | 0.0798072 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0738373 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0725435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0703928 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0690529 |
| RPL7A | ribosomal protein L7a | 0.0652348 |
| TBXT | T-box transcription factor T | 0.0638527 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0626263 |
| PDLIM5 | PDZ and LIM domain 5 | 0.060472 |
| GDA | guanine deaminase | 0.0566788 |
| GRAMD1B | GRAM domain containing 1B | 0.053501 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0514849 |
| CTSL | cathepsin L | 0.0504147 |
| FLNB | filamin B, beta | 0.0483862 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0483054 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.045858 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0449972 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0443673 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0430704 |
| FLNA | filamin A, alpha | 0.0430348 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0419372 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.041901 |
| SFTPA2 | surfactant protein A2 | 0.0415764 |
| ANXA2 | annexin A2 | 0.0414174 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0413735 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0400519 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0395786 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0393312 |
| EZR | ezrin | 0.0388389 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0380746 |
| KYNU | kynureninase | 0.0380588 |
| TMSB4X | thymosin beta 4, X-linked | 0.0380023 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0377038 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0374959 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0370413 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370294 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0368996 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0358648 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.035453 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.034794 |
| INHBA | inhibin, beta A | 0.0345499 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0342221 |
| CTBP2 | C-terminal binding protein 2 | 0.0336667 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0335656 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0330499 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0328816 |
| CD109 | CD109 molecule | 0.032694 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323348 |
| RPL3 | ribosomal protein L3 | 0.0322148 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0321438 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0320235 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0317395 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0315994 |
| SQSTM1 | sequestosome 1 | 0.03116 |
| MAP7 | microtubule-associated protein 7 | 0.0305659 |
| CDH13 | cadherin 13 | 0.0302032 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0302026 |
| CALR | calreticulin | 0.0301166 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0300253 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0299646 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0299543 |
| RPS17 | ribosomal protein S17 | 0.0298863 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0297338 |
| LAMA5 | laminin, alpha 5 | 0.0295813 |
| TPM3 | tropomyosin 3 | 0.0293227 |
| HLA-A | major histocompatibility complex, class I, A | 0.0289308 |
| DUSP4 | dual specificity phosphatase 4 | 0.028217 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0281127 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028014 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.027859 |
| RNF213 | ring finger protein 213 | 0.02776 |
| HLA-B | major histocompatibility complex, class I, B | 0.0270524 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.026519 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0264681 |
| CD44 | CD44 molecule (Indian blood group) | 0.0261507 |
| RPS3 | ribosomal protein S3 | 0.0258896 |
| SVIL | supervillin | 0.0248196 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0243851 |
| SMAD2 | SMAD family member 2 | 0.0241624 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0241368 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0240445 |
| APP | amyloid beta (A4) precursor protein | 0.0236805 |
| MYO10 | myosin X | 0.023549 |
| B2M | beta-2-microglobulin | 0.0234868 |
| FNIP1 | folliculin interacting protein 1 | 0.0232873 |
| C1D | C1D nuclear receptor corepressor | 0.0231743 |
| NTN4 | netrin 4 | 0.0230622 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0230329 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0229261 |
| JUN | jun proto-oncogene | 0.0227056 |
| PRELID2 | PRELI domain containing 2 | 0.0224273 |
| HDAC4 | histone deacetylase 4 | 0.0223452 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219772 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0219534 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.226664 |
| EFNA5 | ephrin-A5 | -0.123689 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114918 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.106165 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0676048 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.060847 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0558059 |
| TXNRD1 | thioredoxin reductase 1 | -0.0546542 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0536906 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0505494 |
| ASPH | aspartate beta-hydroxylase | -0.0500172 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0489779 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427663 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0427622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0417074 |
| SMYD3 | SET and MYND domain containing 3 | -0.0416895 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0412356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0403435 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0383961 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0371085 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0367563 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0354839 |
| NRCAM | neuronal cell adhesion molecule | -0.0348827 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0337502 |
| TMSB10 | thymosin beta 10 | -0.0326083 |
| RPL34 | ribosomal protein L34 | -0.0324923 |
| FTL | ferritin, light polypeptide | -0.0323226 |
| SRGN | serglycin | -0.0315627 |
| NEK7 | NIMA-related kinase 7 | -0.0315386 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0315271 |
| RPS24 | ribosomal protein S24 | -0.0314144 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0295159 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0294687 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0292249 |
| MFF | mitochondrial fission factor | -0.0279662 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0279104 |
| S100A6 | S100 calcium binding protein A6 | -0.0275432 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0273357 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0268192 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267511 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0266582 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0249863 |
| VCL | vinculin | -0.0249285 |
| DIAPH2 | diaphanous-related formin 2 | -0.0239751 |
| GOLGA4 | golgin A4 | -0.0236536 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0233058 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0232067 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0230663 |
| CANX | calnexin | -0.0224594 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0220789 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0219872 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0219433 |
| RBM39 | RNA binding motif protein 39 | -0.0219274 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0217302 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0210856 |
| ZNF804A | zinc finger protein 804A | -0.0210451 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.020531 |
| SBF2 | SET binding factor 2 | -0.0203934 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0202389 |
| PHF20 | PHD finger protein 20 | -0.0200986 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.020092 |
| NCKAP5 | NCK-associated protein 5 | -0.019989 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0199448 |
| RAB10 | RAB10, member RAS oncogene family | -0.0199293 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0196327 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0195192 |
| LMAN1 | lectin, mannose-binding, 1 | -0.019412 |
| NF1 | neurofibromin 1 | -0.0193487 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0193483 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0192045 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0191809 |
| OLA1 | Obg-like ATPase 1 | -0.0191802 |
| RPS23 | ribosomal protein S23 | -0.0191662 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.019111 |
| PALLD | palladin, cytoskeletal associated protein | -0.0190974 |
| PFN1 | profilin 1 | -0.0189383 |
| POU2F1 | POU class 2 homeobox 1 | -0.0188729 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0185792 |
| PTGR1 | prostaglandin reductase 1 | -0.0182987 |
| LSAMP | limbic system-associated membrane protein | -0.0182964 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0180597 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0179618 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0177824 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.017724 |
| TNPO1 | transportin 1 | -0.0175796 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0175751 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0175396 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0175301 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.017397 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0173646 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0173067 |
| TKT | transketolase | -0.017218 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0172025 |
| MAP4 | microtubule-associated protein 4 | -0.0171836 |
| MATR3 | matrin 3 | -0.0171273 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0170519 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0166548 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0166178 |
| GLIS3 | GLIS family zinc finger 3 | -0.0164892 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | -0.0164158 |
