| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.316447 |
| GPC6 | glypican 6 | 0.2003 |
| EFNA5 | ephrin-A5 | 0.186836 |
| PDE10A | phosphodiesterase 10A | 0.176465 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.124607 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.118501 |
| NDRG1 | N-myc downstream regulated 1 | 0.114832 |
| MYOF | myoferlin | 0.108457 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.101715 |
| EZR | ezrin | 0.0877304 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0876531 |
| MAP4 | microtubule-associated protein 4 | 0.0849905 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0828555 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0761349 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0740537 |
| FMN1 | formin 1 | 0.0738823 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0696646 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0689391 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0658354 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0658049 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0629618 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0626083 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0584473 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0568305 |
| DST | dystonin | 0.0564286 |
| CALR | calreticulin | 0.0558272 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0548162 |
| IPO7 | importin 7 | 0.0547272 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0527429 |
| GLIS3 | GLIS family zinc finger 3 | 0.0520511 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0517686 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0517177 |
| LMO7 | LIM domain 7 | 0.0501045 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0482685 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0481589 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0477054 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0475068 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0469136 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0464197 |
| PLEC | plectin | 0.0452381 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0446661 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0444491 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0444055 |
| ACTG1 | actin gamma 1 | 0.0442154 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0441932 |
| MYO10 | myosin X | 0.0438872 |
| CNKSR3 | CNKSR family member 3 | 0.0436287 |
| AREG | amphiregulin | 0.0434472 |
| RBM39 | RNA binding motif protein 39 | 0.0434134 |
| H1-0 | H1.0 linker histone | 0.0414389 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0410163 |
| BRD2 | bromodomain containing 2 | 0.0409333 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0404486 |
| TXNRD1 | thioredoxin reductase 1 | 0.0400057 |
| RPL23 | ribosomal protein L23 | 0.0399167 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0397024 |
| ERBIN | erbb2 interacting protein | 0.0396847 |
| EGFR | epidermal growth factor receptor | 0.0396115 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0391155 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.038992 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0376204 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0374458 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0364158 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0347545 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0325159 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0323475 |
| GOLGA4 | golgin A4 | 0.0319072 |
| RPS25 | ribosomal protein S25 | 0.0318809 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0311433 |
| SETD5 | SET domain containing 5 | 0.0309223 |
| ACTN4 | actinin, alpha 4 | 0.0297616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0289618 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0286674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0285376 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0275322 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0271224 |
| LSAMP | limbic system-associated membrane protein | 0.0270839 |
| SVIL | supervillin | 0.0270032 |
| FHL2 | four and a half LIM domains 2 | 0.026843 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0259242 |
| RPS4X | ribosomal protein S4, X-linked | 0.0248581 |
| ZNF609 | zinc finger protein 609 | 0.0245365 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0241464 |
| IER3 | immediate early response 3 | 0.0240574 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0236554 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0232536 |
| SBF2 | SET binding factor 2 | 0.0231288 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0215194 |
| YAP1 | Yes-associated protein 1 | 0.0206849 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0204599 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0194239 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0192283 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0187434 |
| ANXA2 | annexin A2 | 0.0177677 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0167006 |
| ZNF638 | zinc finger protein 638 | 0.0157117 |
| TPM4 | tropomyosin 4 | 0.0156536 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0156111 |
| FNBP4 | formin binding protein 4 | 0.0153654 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0151981 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.172881 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.161947 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.145219 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.137908 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.127223 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.118804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117952 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.108202 |
| PTMA | prothymosin, alpha | -0.105904 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.103608 |
| PRKCA | protein kinase C, alpha | -0.0966184 |
| RPS6 | ribosomal protein S6 | -0.0915691 |
| VIM | vimentin | -0.0879374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0795144 |
| ASPH | aspartate beta-hydroxylase | -0.0786865 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0783736 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0720392 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0718119 |
| TENM3 | teneurin transmembrane protein 3 | -0.0712764 |
| SPAG9 | sperm associated antigen 9 | -0.0707562 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0702937 |
| FTL | ferritin, light polypeptide | -0.0697441 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0693311 |
| FAM13A | family with sequence similarity 13, member A | -0.0671743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0658532 |
| RAB10 | RAB10, member RAS oncogene family | -0.0632323 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0629235 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0615786 |
| RPLP0 | ribosomal protein, large, P0 | -0.0613044 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0611803 |
| RPL11 | ribosomal protein L11 | -0.0605673 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0599565 |
| TMSB10 | thymosin beta 10 | -0.0597346 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0589822 |
| PGK1 | phosphoglycerate kinase 1 | -0.057839 |
| RPS8 | ribosomal protein S8 | -0.0571528 |
| VMP1 | vacuole membrane protein 1 | -0.055573 |
| HMGA2 | high mobility group AT-hook 2 | -0.0549663 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0543546 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0535655 |
| FMNL2 | formin-like 2 | -0.0528277 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0524491 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0521933 |
| PKM | pyruvate kinase, muscle | -0.0518577 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0513162 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0507982 |
| SLTM | SAFB-like, transcription modulator | -0.0497269 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0495496 |
| MATR3 | matrin 3 | -0.0475844 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0473471 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0446456 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0445612 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0419635 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.0415283 |
| USP34 | ubiquitin specific peptidase 34 | -0.0408886 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0376592 |
| MT2A | metallothionein 2A | -0.0375352 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0367739 |
| TFRC | transferrin receptor | -0.0365398 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0358978 |
| STC1 | stanniocalcin 1 | -0.03589 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0348522 |
| RACK1 | receptor for activated C kinase 1 | -0.0340143 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0339162 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0335433 |
| RPL35A | ribosomal protein L35a | -0.032556 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0320427 |
| RPS23 | ribosomal protein S23 | -0.0313045 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0305753 |
| RORA | RAR-related orphan receptor A | -0.0304371 |
| NFIA | nuclear factor I/A | -0.0302718 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0300805 |
| RPLP2 | ribosomal protein, large, P2 | -0.0298252 |
| TNPO1 | transportin 1 | -0.0289618 |
| RTN4 | reticulon 4 | -0.0286933 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0283698 |
| TOP1 | topoisomerase (DNA) I | -0.027996 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0278718 |
| RPL12 | ribosomal protein L12 | -0.0269648 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0268462 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0264358 |
| PCBP2 | poly(rC) binding protein 2 | -0.0263601 |
| MED13L | mediator complex subunit 13-like | -0.0251168 |
| RPL36 | ribosomal protein L36 | -0.0250845 |
| AFTPH | aftiphilin | -0.0249639 |
| USP3 | ubiquitin specific peptidase 3 | -0.0241737 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0240847 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.023598 |
| MED13 | mediator complex subunit 13 | -0.0217783 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.021402 |
| B2M | beta-2-microglobulin | -0.0211891 |
| RPS12 | ribosomal protein S12 | -0.0208466 |
| RAD51B | RAD51 paralog B | -0.0207662 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0201835 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.01954 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0191225 |
| CCDC47 | coiled-coil domain containing 47 | -0.0187421 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0181251 |
| JMJD1C | jumonji domain containing 1C | -0.0173193 |
| TPD52 | tumor protein D52 | -0.0173167 |
