| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.103417 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0978306 |
| CALR | calreticulin | 0.0970424 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0933833 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0868379 |
| DST | dystonin | 0.0842906 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0767876 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0739198 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0633304 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0633001 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0583627 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0561467 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.055792 |
| COL3A1 | collagen, type III, alpha 1 | 0.0549829 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537487 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0533545 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0533071 |
| NEBL | nebulette | 0.0522082 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0515715 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0494794 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0489046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0468139 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0463547 |
| PCDH18 | protocadherin 18 | 0.0462719 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0460741 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0452365 |
| SFTPA2 | surfactant protein A2 | 0.0449406 |
| TMSB4X | thymosin beta 4, X-linked | 0.044705 |
| FOXP2 | forkhead box P2 | 0.0442454 |
| GSE1 | Gse1 coiled-coil protein | 0.0441573 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0441142 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0440662 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0423243 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0413737 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0407533 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0403079 |
| VEGFA | vascular endothelial growth factor A | 0.0401025 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0398309 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0397155 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0386563 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0385857 |
| MED12L | mediator complex subunit 12-like | 0.0381965 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0367703 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0359082 |
| NOTCH2 | notch 2 | 0.0358926 |
| TENM3 | teneurin transmembrane protein 3 | 0.0357737 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0356157 |
| CCN2 | cellular communication network factor 2 | 0.0351167 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.034784 |
| CLSTN1 | calsyntenin 1 | 0.0344948 |
| MEIS2 | Meis homeobox 2 | 0.0344447 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0343519 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0340587 |
| FOXN3 | forkhead box N3 | 0.0339639 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0338834 |
| PLD3 | phospholipase D family, member 3 | 0.0337776 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0333471 |
| STMN1 | stathmin 1 | 0.0331797 |
| SMYD3 | SET and MYND domain containing 3 | 0.0325485 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0325188 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0322423 |
| B2M | beta-2-microglobulin | 0.0321144 |
| RPL7A | ribosomal protein L7a | 0.0318309 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0312553 |
| PHF3 | PHD finger protein 3 | 0.030772 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0300184 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0298272 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0298256 |
| ACTG1 | actin gamma 1 | 0.0292597 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.029255 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.029026 |
| RPL3 | ribosomal protein L3 | 0.0289081 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0288979 |
| PTMA | prothymosin, alpha | 0.0287769 |
| CCNYL1 | cyclin Y-like 1 | 0.028346 |
| FAM168A | family with sequence similarity 168, member A | 0.0280222 |
| INTS6 | integrator complex subunit 6 | 0.0280043 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0278672 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0277497 |
| SVIL | supervillin | 0.0275329 |
| MGA | MGA, MAX dimerization protein | 0.0274555 |
| ECT2 | epithelial cell transforming 2 | 0.0273275 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0271107 |
| FOXK1 | forkhead box K1 | 0.0270439 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0269518 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.02683 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0265251 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0265172 |
| EXOC6B | exocyst complex component 6B | 0.0264575 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0262611 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0262415 |
| MEF2A | myocyte enhancer factor 2A | 0.0261544 |
| MSH2 | mutS homolog 2 | 0.026123 |
| ZNF516 | zinc finger protein 516 | 0.0261115 |
| SCFD1 | sec1 family domain containing 1 | 0.0260967 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0260497 |
| CSNK1D | casein kinase 1, delta | 0.0260399 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0258269 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0258044 |
| TMSB10 | thymosin beta 10 | 0.0257473 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121538 |
| GPC3 | glypican 3 | -0.105416 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.102665 |
| ZNF292 | zinc finger protein 292 | -0.0837595 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0817233 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0801011 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0782761 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.072741 |
| VIM | vimentin | -0.0705487 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0703646 |
| QKI | QKI, KH domain containing, RNA binding | -0.0680553 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0626551 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0620798 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0584541 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0581046 |
| LRRC4C | leucine rich repeat containing 4C | -0.0569581 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.056475 |
| RBM39 | RNA binding motif protein 39 | -0.0542025 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0533255 |
| NCAM2 | neural cell adhesion molecule 2 | -0.052252 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0491847 |
| PHIP | pleckstrin homology domain interacting protein | -0.0475258 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0472336 |
| USP3 | ubiquitin specific peptidase 3 | -0.0468296 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0465933 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0455078 |
| RPS16 | ribosomal protein S16 | -0.0453467 |
| VGLL3 | vestigial-like family member 3 | -0.0450508 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.042093 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0408163 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0401774 |
| LDHA | lactate dehydrogenase A | -0.0401638 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0400798 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0400302 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0398438 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0397616 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0394865 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0383932 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0375467 |
| RPS27A | ribosomal protein S27a | -0.0373005 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0372749 |
| PFN1 | profilin 1 | -0.0371946 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0369854 |
| SHROOM3 | shroom family member 3 | -0.036526 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0363284 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0358486 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0354707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0351005 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0348432 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0347885 |
| HMGB1 | high mobility group box 1 | -0.0346777 |
| CBX3 | chromobox homolog 3 | -0.0346685 |
| CDC73 | cell division cycle 73 | -0.0344948 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0343179 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0339821 |
| RHEB | Ras homolog enriched in brain | -0.0338155 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0334216 |
| PARD3 | par-3 family cell polarity regulator | -0.0334143 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0333736 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0329902 |
| ITGAV | integrin, alpha V | -0.0328781 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.032805 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0327351 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0326781 |
| HBP1 | HMG-box transcription factor 1 | -0.032468 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0324458 |
| RPL7 | ribosomal protein L7 | -0.0324267 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0319431 |
| MAP4 | microtubule-associated protein 4 | -0.0319021 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0316037 |
| ZNF644 | zinc finger protein 644 | -0.0315022 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.031139 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0309009 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0308169 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0307294 |
| AZIN1 | antizyme inhibitor 1 | -0.0306199 |
| RPS2 | ribosomal protein S2 | -0.030491 |
| MB21D2 | Mab-21 domain containing 2 | -0.0303179 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0301548 |
| NOP58 | NOP58 ribonucleoprotein | -0.0298076 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0296779 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.029642 |
| RPS6 | ribosomal protein S6 | -0.0296149 |
| USP25 | ubiquitin specific peptidase 25 | -0.0295628 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.029487 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0293908 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0293487 |
| MTF2 | metal response element binding transcription factor 2 | -0.0292956 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0291331 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0288752 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0288178 |
| DOCK7 | dedicator of cytokinesis 7 | -0.028778 |
| OLA1 | Obg-like ATPase 1 | -0.0286158 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0285103 |
| CALCR | calcitonin receptor | -0.0285093 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0284586 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0284028 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0283432 |
| RFX7 | regulatory factor X, 7 | -0.0282895 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0282831 |
