| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.346064 |
| COL6A3 | collagen, type VI, alpha 3 | 0.225504 |
| ADM | adrenomedullin | 0.150893 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.149599 |
| FN1 | fibronectin 1 | 0.145064 |
| VEGFA | vascular endothelial growth factor A | 0.144666 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.141589 |
| TMSB4X | thymosin beta 4, X-linked | 0.104278 |
| NDRG1 | N-myc downstream regulated 1 | 0.0998017 |
| CALR | calreticulin | 0.0943696 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0784034 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0763843 |
| SMAD3 | SMAD family member 3 | 0.0724273 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0668561 |
| HLA-B | major histocompatibility complex, class I, B | 0.066637 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0603541 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0598466 |
| NAV2 | neuron navigator 2 | 0.0593753 |
| FLNB | filamin B, beta | 0.0567456 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0564495 |
| SFTPA2 | surfactant protein A2 | 0.0541481 |
| APP | amyloid beta (A4) precursor protein | 0.0513295 |
| RPL7A | ribosomal protein L7a | 0.0510203 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0505071 |
| PDE10A | phosphodiesterase 10A | 0.0486518 |
| ANXA2 | annexin A2 | 0.048312 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.044227 |
| B2M | beta-2-microglobulin | 0.0437671 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432137 |
| SDC4 | syndecan 4 | 0.0426212 |
| FMNL2 | formin-like 2 | 0.0419662 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0385891 |
| COL5A1 | collagen, type V, alpha 1 | 0.0378003 |
| CEP250 | centrosomal protein 250kDa | 0.0365999 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0360546 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0360474 |
| AHNAK | AHNAK nucleoprotein | 0.035803 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0354903 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0353979 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0335531 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0332791 |
| CTSB | cathepsin B | 0.0331994 |
| HLA-C | major histocompatibility complex, class I, C | 0.0331888 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0319328 |
| MLPH | melanophilin | 0.0312888 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0306303 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0305078 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0302313 |
| LOXL2 | lysyl oxidase-like 2 | 0.0302184 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301272 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0299128 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0297165 |
| MYOF | myoferlin | 0.0285038 |
| FLNA | filamin A, alpha | 0.0280696 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0277611 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0275895 |
| OPTN | optineurin | 0.0272243 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0271241 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0270505 |
| OGA | O-GlcNAcase | 0.026989 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0266295 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0265287 |
| ARRDC3 | arrestin domain containing 3 | 0.0263687 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0257568 |
| YEATS2 | YEATS domain containing 2 | 0.0256592 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0255086 |
| LDHA | lactate dehydrogenase A | 0.025446 |
| TNS3 | tensin 3 | 0.0249573 |
| MT2A | metallothionein 2A | 0.0249339 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0248818 |
| HLA-A | major histocompatibility complex, class I, A | 0.0247637 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.024687 |
| NEK6 | NIMA-related kinase 6 | 0.0245871 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0242664 |
| JUN | jun proto-oncogene | 0.0240559 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0240031 |
| THBS2 | thrombospondin 2 | 0.0239757 |
| PRELID2 | PRELI domain containing 2 | 0.0238764 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0236356 |
| PGK1 | phosphoglycerate kinase 1 | 0.0234 |
| TRAM2 | translocation associated membrane protein 2 | 0.023096 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0230579 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0229325 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0228652 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0227531 |
| ANXA1 | annexin A1 | 0.0227223 |
| FAM219A | family with sequence similarity 219, member A | 0.0225956 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0225642 |
| HELZ | helicase with zinc finger | 0.0224597 |
| RPL4 | ribosomal protein L4 | 0.0224264 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0223084 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0223076 |
| KIF13A | kinesin family member 13A | 0.0220778 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0219602 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.021795 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0215646 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0212298 |
| FAM13A | family with sequence similarity 13, member A | 0.021181 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021094 |
| RPS3 | ribosomal protein S3 | 0.0210505 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.11626 |
| VCL | vinculin | -0.0840725 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0749327 |
| GLIS3 | GLIS family zinc finger 3 | -0.0743847 |
| BICC1 | BicC family RNA binding protein 1 | -0.063347 |
| HMGA2 | high mobility group AT-hook 2 | -0.0524963 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0512212 |
| KYNU | kynureninase | -0.0468867 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0466613 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0427849 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0416403 |
| NABP1 | nucleic acid binding protein 1 | -0.041151 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0410803 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0400229 |
| CTSD | cathepsin D | -0.0399519 |
| IER3 | immediate early response 3 | -0.0380752 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0366659 |
| RPS24 | ribosomal protein S24 | -0.0360154 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0355417 |
| CDH13 | cadherin 13 | -0.0351033 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346557 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0339082 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0318851 |
| FRMD4A | FERM domain containing 4A | -0.0317822 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0311141 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0310389 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0309077 |
| RAI14 | retinoic acid induced 14 | -0.0307865 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0289778 |
| FTL | ferritin, light polypeptide | -0.028974 |
| TMSB10 | thymosin beta 10 | -0.0282827 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0279162 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0275413 |
| HMGA1 | high mobility group AT-hook 1 | -0.027105 |
| CLIC4 | chloride intracellular channel 4 | -0.0268398 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0266581 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0265668 |
| DIAPH2 | diaphanous-related formin 2 | -0.0264786 |
| ERBIN | erbb2 interacting protein | -0.0260177 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025718 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0256699 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0254934 |
| DST | dystonin | -0.0252827 |
| RPLP0 | ribosomal protein, large, P0 | -0.0249914 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0249714 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0249305 |
| COL1A1 | collagen, type I, alpha 1 | -0.0248415 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0247991 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0245292 |
| TAPBP | TAP binding protein (tapasin) | -0.0239735 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0237962 |
| KLHL5 | kelch-like family member 5 | -0.0237837 |
| RRBP1 | ribosome binding protein 1 | -0.0233893 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0224652 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0221272 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0220485 |
| CENPF | centromere protein F, 350/400kDa | -0.0219214 |
| INSIG1 | insulin induced gene 1 | -0.0216055 |
| RPS21 | ribosomal protein S21 | -0.0213041 |
| PALLD | palladin, cytoskeletal associated protein | -0.0212273 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.020807 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0206159 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0205071 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0202901 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0202528 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0198409 |
| RPL34 | ribosomal protein L34 | -0.0197936 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0197245 |
| NRN1 | neuritin 1 | -0.0196696 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0196016 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0195727 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0195548 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0192598 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0191102 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.019031 |
| TMEM132D | transmembrane protein 132D | -0.0188085 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0186159 |
| PMP22 | peripheral myelin protein 22 | -0.0184941 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0184099 |
| PLSCR1 | phospholipid scramblase 1 | -0.0183313 |
| COL1A2 | collagen, type I, alpha 2 | -0.0182879 |
| INHBA | inhibin, beta A | -0.0181171 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.017982 |
| GNAS | GNAS complex locus | -0.0179124 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0178247 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0177701 |
| RPL35A | ribosomal protein L35a | -0.0177676 |
| FBXO11 | F-box protein 11 | -0.0176032 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0175818 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0172851 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0172272 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0171323 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0167554 |
| ZNF644 | zinc finger protein 644 | -0.0166479 |
| TAGLN2 | transgelin 2 | -0.016632 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0165956 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0165681 |
| SRGN | serglycin | -0.0164681 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.0163775 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.016358 |
