Ceruletide Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction. (Chemical Entities of Biological Interest Ontology, CHEBI_59219)
External Link http://ctdbase.org/detail.go?type=chem&acc=D002108
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Genes

15 genes/proteins interacting with the chemical Ceruletide from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ALB albumin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CTSB cathepsin B
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
MPO myeloperoxidase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
TNF tumor necrosis factor
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase