| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/25074887 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Cetrorelix relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | 1.83 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | 1.14 |
| MRPL50 | mitochondrial ribosomal protein L50 | 0.68 |
| APOE | apolipoprotein E | 0.66 |
| DNAH1 | dynein, axonemal, heavy chain 1 | 0.57 |
| S100A5 | S100 calcium binding protein A5 | 0.56 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.56 |
| KRT8 | keratin 8, type II | 0.53 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.53 |
| FAM241B | family with sequence similarity 241 member B | 0.53 |
| MED29 | mediator complex subunit 29 | 0.52 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.52 |
| ZNF428 | zinc finger protein 428 | 0.49 |
| DZIP3 | DAZ interacting zinc finger protein 3 | 0.49 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.48 |
| KRT222 | keratin 222, type II | 0.47 |
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | 0.46 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.45 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.45 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.45 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.44 |
| IMPACT | impact RWD domain protein | 0.44 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.43 |
| ADI1 | acireductone dioxygenase 1 | 0.42 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.42 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.42 |
| FMNL1 | formin-like 1 | 0.41 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.4 |
| NUCB1 | nucleobindin 1 | 0.4 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.4 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.39 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.39 |
| BID | BH3 interacting domain death agonist | 0.39 |
| TPM1 | tropomyosin 1 (alpha) | 0.39 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.39 |
| CCDC150 | coiled-coil domain containing 150 | 0.38 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 0.38 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.38 |
| GUK1 | guanylate kinase 1 | 0.37 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.37 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.37 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.37 |
| RNF185 | ring finger protein 185 | 0.37 |
| PTMA | prothymosin, alpha | 0.37 |
| VPS26C | VPS26 endosomal protein sorting factor C | 0.36 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.36 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | 0.36 |
| PTPRS | protein tyrosine phosphatase, receptor type, S | 0.36 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.36 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.35 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein | 0.35 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.35 |
| MED8 | mediator complex subunit 8 | 0.35 |
| ERH | enhancer of rudimentary homolog (Drosophila) | 0.34 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 0.34 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | 0.34 |
| MAGEF1 | melanoma antigen family F1 | 0.34 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.34 |
| ZNF354A | zinc finger protein 354A | 0.34 |
| TXN2 | thioredoxin 2 | 0.34 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | 0.33 |
| POTEI | POTE ankyrin domain family, member I | 0.33 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.33 |
| LTO1 | LTO1 maturation factor of ABCE1 | 0.33 |
| HLA-E | major histocompatibility complex, class I, E | 0.33 |
| YAP1 | Yes-associated protein 1 | 0.33 |
| MTFR1L | mitochondrial fission regulator 1-like | 0.32 |
| CD320 | CD320 molecule | 0.32 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.32 |
| BANF1 | barrier to autointegration factor 1 | 0.32 |
| SFR1 | SWI5-dependent recombination repair 1 | 0.32 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.32 |
| CCDC57 | coiled-coil domain containing 57 | 0.32 |
| RPLP1 | ribosomal protein, large, P1 | 0.32 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.32 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.31 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.31 |
| ABRACL | ABRA C-terminal like | 0.31 |
| LENG9 | leukocyte receptor cluster (LRC) member 9 | 0.31 |
| AGRN | agrin | 0.31 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | 0.31 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.31 |
| COMMD6 | COMM domain containing 6 | 0.31 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.31 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.31 |
| SDC4 | syndecan 4 | 0.31 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.3 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.3 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | 0.3 |
| HIST1H1T | histone cluster 1, H1t | 0.3 |
| FER1L5 | fer-1-like family member 5 | 0.3 |
| DESI1 | desumoylating isopeptidase 1 | 0.3 |
| TMEM237 | transmembrane protein 237 | 0.3 |
| RPL27A | ribosomal protein L27a | 0.3 |
| COX5A | cytochrome c oxidase subunit Va | 0.29 |
| RBAK | RB-associated KRAB zinc finger | 0.29 |
| CHURC1 | churchill domain containing 1 | 0.29 |
| CACUL1 | CDK2-associated, cullin domain 1 | 0.29 |
| LGALSL | lectin, galactoside-binding-like | 0.29 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.29 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TAZ | tafazzin | -2.97 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -1.93 |
| STK17A | serine/threonine kinase 17a | -1.39 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.9 |
| NAV2 | neuron navigator 2 | -0.88 |
| PTOV1 | prostate tumor overexpressed 1 | -0.88 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.76 |
| PLCL2 | phospholipase C-like 2 | -0.72 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.72 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | -0.7 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.64 |
| HRH1 | histamine receptor H1 | -0.56 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.54 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.54 |
| TRIM8 | tripartite motif containing 8 | -0.52 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.52 |
| FAAP24 | FA core complex associated protein 24 | -0.51 |
| LPIN2 | lipin 2 | -0.5 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | -0.5 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | -0.49 |
| MT-CO1 | cytochrome c oxidase subunit I | -0.48 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.48 |
| TMEM101 | transmembrane protein 101 | -0.46 |
| GLS | glutaminase | -0.45 |
| SPPL2A | signal peptide peptidase like 2A | -0.44 |
| FANCL | Fanconi anemia, complementation group L | -0.44 |
| HM13 | histocompatibility (minor) 13 | -0.43 |
| CIC | capicua transcriptional repressor | -0.43 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | -0.43 |
| ZNF711 | zinc finger protein 711 | -0.42 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.41 |
| KLHL25 | kelch-like family member 25 | -0.41 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.41 |
| ATG4D | autophagy related 4D, cysteine peptidase | -0.4 |
| ERG28 | ergosterol biosynthesis 28 homolog | -0.39 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | -0.39 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.38 |
| TRIML2 | tripartite motif family-like 2 | -0.38 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.37 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.37 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.37 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.37 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.37 |
| MT-ND4 | NADH dehydrogenase, subunit 4 (complex I) | -0.36 |
| IRF2 | interferon regulatory factor 2 | -0.36 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.36 |
| TNIP2 | TNFAIP3 interacting protein 2 | -0.36 |
| USP12 | ubiquitin specific peptidase 12 | -0.36 |
| NRBF2 | nuclear receptor binding factor 2 | -0.35 |
| NHEJ1 | nonhomologous end-joining factor 1 | -0.35 |
| BSDC1 | BSD domain containing 1 | -0.35 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.35 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like | -0.35 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | -0.35 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -0.34 |
| ADIPOR1 | adiponectin receptor 1 | -0.34 |
| MYL9 | myosin, light chain 9, regulatory | -0.34 |
| JRKL | JRK-like | -0.34 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.34 |
| FUNDC1 | FUN14 domain containing 1 | -0.33 |
| RIC1 | RAB6A GEF complex partner 1 | -0.33 |
| PEX7 | peroxisomal biogenesis factor 7 | -0.33 |
| CENPO | centromere protein O | -0.33 |
| ASB7 | ankyrin repeat and SOCS box containing 7 | -0.32 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.32 |
| ZBTB5 | zinc finger and BTB domain containing 5 | -0.32 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.32 |
| TMEM104 | transmembrane protein 104 | -0.32 |
| TOB2 | transducer of ERBB2, 2 | -0.31 |
| PRMT2 | protein arginine methyltransferase 2 | -0.31 |
| RPL37 | ribosomal protein L37 | -0.31 |
| SNAP91 | synaptosomal-associated protein, 91kDa | -0.31 |
| PRXL2A | peroxiredoxin like 2A | -0.31 |
| ARSB | arylsulfatase B | -0.31 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | -0.31 |
| TRIM5 | tripartite motif containing 5 | -0.3 |
| ANTXR1 | anthrax toxin receptor 1 | -0.3 |
| SMIM12 | small integral membrane protein 12 | -0.3 |
| INPP5J | inositol polyphosphate-5-phosphatase J | -0.3 |
| CLOCK | clock circadian regulator | -0.3 |
| SGCE | sarcoglycan, epsilon | -0.3 |
| SEPTIN4 | septin 4 | -0.29 |
| ZNF791 | zinc finger protein 791 | -0.29 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.29 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.29 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -0.29 |
| CLDN3 | claudin 3 | -0.29 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.28 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.28 |
| TMEM263 | transmembrane protein 263 | -0.28 |
| SMOX | spermine oxidase | -0.28 |
| NAGLU | N-acetylglucosaminidase, alpha | -0.28 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.28 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.28 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.27 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.27 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.27 |
| CHPF2 | chondroitin polymerizing factor 2 | -0.27 |
| KDM8 | lysine (K)-specific demethylase 8 | -0.27 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.27 |
