Cheilitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A lip disease characterized by the inflammation of the lips; which may include the perioral skin, the vermilion border and the labial mucosa. (Human Disease Ontology, DOID_1762)
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Genes

152 genes co-occuring with the disease Cheilitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 2.035
TNF tumor necrosis factor 1.868
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.861
CRP C-reactive protein, pentraxin-related 1.832
CD8A CD8a molecule 1.782
IL6 interleukin 6 1.752
RARS1 arginyl-tRNA synthetase 1 1.704
GCG glucagon 1.697
IL17A interleukin 17A 1.683
ALB albumin 1.66
IFNG interferon, gamma 1.624
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 1.621
IL1B interleukin 1, beta 1.618
FLG filaggrin 1.592
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.584
IL1A interleukin 1, alpha 1.561
TP53 tumor protein p53 1.56
IFNA1 interferon, alpha 1 1.545
IL22 interleukin 22 1.541
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.531
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.53
CAST calpastatin 1.528
ACE angiotensin I converting enzyme 1.527
IL10 interleukin 10 1.522
PKP1 plakophilin 1 1.509
AIRE autoimmune regulator 1.485
FLG2 filaggrin family member 2 1.482
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.479
LTF lactotransferrin 1.47
CXCL8 chemokine (C-X-C motif) ligand 8 1.466
IL4 interleukin 4 1.462
KRT10 keratin 10, type I 1.447
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.436
IFNA2 interferon, alpha 2 1.436
DSG3 desmoglein 3 1.408
IL2 interleukin 2 1.404
INS insulin 1.396
IFNA17 interferon, alpha 17 1.394
MEN1 multiple endocrine neoplasia I 1.392
IFNA10 interferon, alpha 10 1.383
DSG1 desmoglein 1 1.379
IFNA4 interferon, alpha 4 1.378
IFNA16 interferon, alpha 16 1.37
IFNA7 interferon, alpha 7 1.37
IFNA8 interferon, alpha 8 1.369
IFNA21 interferon, alpha 21 1.369
IFNA14 interferon, alpha 14 1.369
IFNA6 interferon, alpha 6 1.368
IFNA5 interferon, alpha 5 1.367
IFNA13 interferon, alpha 13 1.366
SST somatostatin 1.36
CD1B CD1b molecule 1.356
CD1E CD1e molecule 1.353
RARG retinoic acid receptor, gamma 1.347
CD1A CD1a molecule 1.343
GAST gastrin 1.341
IL17F interleukin 17F 1.335
CD1C CD1c molecule 1.332
CARD14 caspase recruitment domain family, member 14 1.321
LMBRD1 LMBR1 domain containing 1 1.313
KRT6A keratin 6A, type II 1.31
CD1D CD1d molecule 1.303
TGFB1 transforming growth factor, beta 1 1.303
HTN3 histatin 3 1.301
IL13 interleukin 13 1.299
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 1.299
STATH statherin 1.299
ACE2 angiotensin I converting enzyme 2 1.274
POMC proopiomelanocortin 1.263
SLURP1 secreted LY6/PLAUR domain containing 1 1.255
IL5 interleukin 5 1.25
SSB Sjogren syndrome antigen B (autoantigen La) 1.247
CLEC7A C-type lectin domain family 7, member A 1.244
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.241
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 1.24
DSP desmoplakin 1.237
TLR2 toll-like receptor 2 1.224
TRPV3 transient receptor potential cation channel, subfamily V, member 3 1.22
KRT16 keratin 16, type I 1.218
ELN elastin 1.213
KNG1 kininogen 1 1.211
CARD9 caspase recruitment domain family, member 9 1.209
KRT6B keratin 6B, type II 1.205
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.205
VIP vasoactive intestinal peptide 1.204
CD274 CD274 molecule 1.203
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.202
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.198
FOXP3 forkhead box P3 1.189
A2ML1 alpha-2-macroglobulin-like 1 1.183
CAMP cathelicidin antimicrobial peptide 1.18
CSF3 colony stimulating factor 3 (granulocyte) 1.161
PPY pancreatic polypeptide 1.161
CDKN2A cyclin-dependent kinase inhibitor 2A 1.16
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.153
DEFB4A defensin, beta 4A 1.143
TRIM21 tripartite motif containing 21 1.133
IL17RA interleukin 17 receptor A 1.132
MALT1 MALT1 paracaspase 1.109
PTH parathyroid hormone 1.106
IL36RN interleukin 36 receptor antagonist 1.105
CHGA chromogranin A 1.102
TOR1A torsin family 1, member A (torsin A) 1.1
IVL involucrin 1.1
HAMP hepcidin antimicrobial peptide 1.096
KRT14 keratin 14, type I 1.094
MMP9 matrix metallopeptidase 9 1.093
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 1.093
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.09
COL17A1 collagen, type XVII, alpha 1 1.09
PRTN3 proteinase 3 1.084
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.081
DOCK8 dedicator of cytokinesis 8 1.079
RFK riboflavin kinase 1.076
KRT15 keratin 15, type I 1.073
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.073
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.07
DST dystonin 1.067
STAT1 signal transducer and activator of transcription 1, 91kDa 1.066
EGF epidermal growth factor 1.065
PXDNL peroxidasin-like 1.063
PXDN peroxidasin 1.061
CD68 CD68 molecule 1.061
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.061
PNPO pyridoxamine 5'-phosphate oxidase 1.059
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.046
TGM1 transglutaminase 1 1.045
KRT13 keratin 13, type I 1.042
EGFR epidermal growth factor receptor 1.041
CARMIL2 capping protein regulator and myosin 1 linker 2 1.038
SDC1 syndecan 1 1.038
FERMT1 fermitin family member 1 1.037
PDCD1 programmed cell death 1 1.035
IL18 interleukin 18 1.034
IL12RB1 interleukin 12 receptor, beta 1 1.034
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.033
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.03
NOD2 nucleotide-binding oligomerization domain containing 2 1.028
IL23A interleukin 23, alpha subunit p19 1.026
CCL2 chemokine (C-C motif) ligand 2 1.022
CD83 CD83 molecule 1.014
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.012
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 1.011
AMN amnion associated transmembrane protein 1.011
JAK1 Janus kinase 1 1.007
MPO myeloperoxidase 1.007
DELE1 DAP3 binding cell death enhancer 1 1.006
TAS2R14 taste receptor, type 2, member 14 1.006
TSLP thymic stromal lymphopoietin 1.004
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.003
IGF1 insulin-like growth factor 1 (somatomedin C) 1.0
FLAD1 flavin adenine dinucleotide synthetase 1 1.0