Chest Pain Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the chest. (Human Phenotype Ontology, HP_0100749)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D002637
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Genes

536 genes/proteins associated with the disease Chest Pain from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CRH corticotropin releasing hormone 2.88009
FOS FBJ murine osteosarcoma viral oncogene homolog 2.48298
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.43209
TNF tumor necrosis factor 2.41344
IL6 interleukin 6 2.37572
BCL2 B-cell CLL/lymphoma 2 2.37363
IL1B interleukin 1, beta 2.32541
REN renin 2.31551
MAPK3 mitogen-activated protein kinase 3 2.3112
MAPK1 mitogen-activated protein kinase 1 2.30496
EDN1 endothelin 1 2.24555
BAX BCL2-associated X protein 2.23543
FAS Fas cell surface death receptor 2.22207
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.21883
VEGFA vascular endothelial growth factor A 2.20256
TGFB1 transforming growth factor, beta 1 2.19573
SOD2 superoxide dismutase 2, mitochondrial 2.19389
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.1836
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.17108
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.1576
CAT catalase 2.15185
NOS2 nitric oxide synthase 2, inducible 2.14338
IL10 interleukin 10 2.1374
JUN jun proto-oncogene 2.13316
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.12565
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.12114
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.11199
CALCA calcitonin-related polypeptide alpha 2.10841
EGR1 early growth response 1 2.10807
CXCL8 chemokine (C-X-C motif) ligand 8 2.09927
MMP2 matrix metallopeptidase 2 2.06525
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.05458
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.05005
BCL2L1 BCL2-like 1 2.01691
MMP9 matrix metallopeptidase 9 2.01595
BDNF brain-derived neurotrophic factor 2.00703
TP53 tumor protein p53 2.00508
HMOX1 heme oxygenase 1 2.00412
CCL2 chemokine (C-C motif) ligand 2 1.98011
NPPA natriuretic peptide A 1.97244
IFNG interferon, gamma 1.96685
IL1A interleukin 1, alpha 1.95843
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.95843
CCND1 cyclin D1 1.95721
PARP1 poly (ADP-ribose) polymerase 1 1.94642
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.93185
CLU clusterin 1.91067
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.90656
GSTP1 glutathione S-transferase pi 1 1.90459
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.89976
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.8978
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.89731
NPY neuropeptide Y 1.89504
TAC1 tachykinin, precursor 1 1.88059
MAP2K1 mitogen-activated protein kinase kinase 1 1.86873
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.86062
NOS3 nitric oxide synthase 3 (endothelial cell) 1.85887
SOD1 superoxide dismutase 1, soluble 1.85747
TIMP1 TIMP metallopeptidase inhibitor 1 1.85573
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.85239
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.84799
NPPB natriuretic peptide B 1.84323
FASLG Fas ligand (TNF superfamily, member 6) 1.8418
ICAM1 intercellular adhesion molecule 1 1.83877
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.83681
VCAM1 vascular cell adhesion molecule 1 1.81702
LPL lipoprotein lipase 1.81375
EGFR epidermal growth factor receptor 1.7977
LEP leptin 1.79713
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.78378
FGF2 fibroblast growth factor 2 (basic) 1.77199
MAPK14 mitogen-activated protein kinase 14 1.77063
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.77024
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.76636
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.7542
DUSP1 dual specificity phosphatase 1 1.75261
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.74119
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.73818
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.72821
NGF nerve growth factor (beta polypeptide) 1.72219
SPP1 secreted phosphoprotein 1 1.72096
JUNB jun B proto-oncogene 1.71255
PENK proenkephalin 1.69888
PRKCD protein kinase C, delta 1.68633
DDIT3 DNA-damage-inducible transcript 3 1.68169
COL1A1 collagen, type I, alpha 1 1.68084
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.6774
RGS4 regulator of G-protein signaling 4 1.66943
IL4 interleukin 4 1.66167
OXT oxytocin/neurophysin I prepropeptide 1.65511
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.65511
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.65159
MAPK8 mitogen-activated protein kinase 8 1.6419
AVP arginine vasopressin 1.63989
IL2 interleukin 2 1.63451
BTG2 BTG family, member 2 1.63116
PLAT plasminogen activator, tissue 1.62646
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.62335
MPO myeloperoxidase 1.62036
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.62036
FN1 fibronectin 1 1.62036
CREB1 cAMP responsive element binding protein 1 1.59896
RB1 retinoblastoma 1 1.59731
GFAP glial fibrillary acidic protein 1.59474
POMC proopiomelanocortin 1.59241
CKB creatine kinase, brain 1.59148
TH tyrosine hydroxylase 1.58279
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.58232
ADRB2 adrenoceptor beta 2, surface 1.57877
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.57759
CCND3 cyclin D3 1.57712
SELL selectin L 1.57066
MAOA monoamine oxidase A 1.5619
MYL9 myosin, light chain 9, regulatory 1.55995
GAST gastrin 1.55995
EGF epidermal growth factor 1.55946
PRL prolactin 1.555
NUPR1 nuclear protein, transcriptional regulator, 1 1.55353
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.55255
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.54961
CDK2 cyclin-dependent kinase 2 1.54257
IGF1 insulin-like growth factor 1 (somatomedin C) 1.54159
LCN2 lipocalin 2 1.54135
GDF15 growth differentiation factor 15 1.53917
G6PD glucose-6-phosphate dehydrogenase 1.53772
ATF3 activating transcription factor 3 1.53699
ALB albumin 1.53699
GJA1 gap junction protein, alpha 1, 43kDa 1.53135
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.53012
VIM vimentin 1.52816
PPARG peroxisome proliferator-activated receptor gamma 1.52439
MMP3 matrix metallopeptidase 3 1.52187
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.5186
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.5186
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.5138
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.5128
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.5123
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.50903
ODC1 ornithine decarboxylase 1 1.50751
CYCS cytochrome c, somatic 1.50725
TNNI3 troponin I type 3 (cardiac) 1.50524
ADRB1 adrenoceptor beta 1 1.50223
TYMS thymidylate synthetase 1.49558
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.49381
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.49304
CFLAR CASP8 and FADD-like apoptosis regulator 1.48633
KLF4 Kruppel-like factor 4 (gut) 1.48531
CYR61 cysteine-rich, angiogenic inducer, 61 1.48428
G0S2 G0/G1 switch 2 1.48248
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.47504
NOX4 NADPH oxidase 4 1.47426
CNR1 cannabinoid receptor 1 (brain) 1.45857
MMP13 matrix metallopeptidase 13 1.45458
GNAS GNAS complex locus 1.45036
PPARA peroxisome proliferator-activated receptor alpha 1.44899
CTSL cathepsin L 1.44763
CCNB1 cyclin B1 1.44382
PRKCZ protein kinase C, zeta 1.44273
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.43946
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.43809
ADORA1 adenosine A1 receptor 1.43727
ADRB3 adrenoceptor beta 3 1.43266
INS insulin 1.4275
LGALS3 lectin, galactoside-binding, soluble, 3 1.42481
GSTM1 glutathione S-transferase mu 1 1.42428
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.41035
PRKCE protein kinase C, epsilon 1.41035
PKM pyruvate kinase, muscle 1.40815
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.40732
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.40732
GSK3B glycogen synthase kinase 3 beta 1.40541
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.39813
NOS1 nitric oxide synthase 1 (neuronal) 1.39619
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.3917
DUSP6 dual specificity phosphatase 6 1.3917
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.38918
CCNE1 cyclin E1 1.3878
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.38724
BIRC5 baculoviral IAP repeat containing 5 1.38669
COMT catechol-O-methyltransferase 1.38355
CD151 CD151 molecule (Raph blood group) 1.38043
KRT8 keratin 8, type II 1.37846
GADD45A growth arrest and DNA-damage-inducible, alpha 1.37561
ADORA2A adenosine A2a receptor 1.37475
GCG glucagon 1.37475
PRKCA protein kinase C, alpha 1.37475
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.37475
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.37047
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.36961
EDNRB endothelin receptor type B 1.36735
TGFB2 transforming growth factor, beta 2 1.36533
NRP1 neuropilin 1 1.36076
MMP1 matrix metallopeptidase 1 1.35763
SGK1 serum/glucocorticoid regulated kinase 1 1.35271
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.35098
PTEN phosphatase and tensin homolog 1.34926
CXCR4 chemokine (C-X-C motif) receptor 4 1.34869
F3 coagulation factor III (thromboplastin, tissue factor) 1.34869
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.34576
GSK3A glycogen synthase kinase 3 alpha 1.34256
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.33938
ATF4 activating transcription factor 4 1.33642
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.33434
CDK5 cyclin-dependent kinase 5 1.33257
GPX1 glutathione peroxidase 1 1.33199
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.33169
CAV1 caveolin 1, caveolae protein, 22kDa 1.33022
MCL1 myeloid cell leukemia 1 1.32964
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.32816
TRIM2 tripartite motif containing 2 1.32756
SRGN serglycin 1.32756
GAL galanin/GMAP prepropeptide 1.32726
PCNA proliferating cell nuclear antigen 1.32667
EGR2 early growth response 2 1.32667
CD44 CD44 molecule (Indian blood group) 1.32637
DDIT4 DNA-damage-inducible transcript 4 1.32428
TK2 thymidine kinase 2, mitochondrial 1.32369
TIMP2 TIMP metallopeptidase inhibitor 2 1.32251
COX5A cytochrome c oxidase subunit Va 1.31807
STC2 stanniocalcin 2 1.31716
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.31387
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.31297
PLCG1 phospholipase C, gamma 1 1.31059
CP ceruloplasmin (ferroxidase) 1.30727
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.30696
HSPA1A heat shock 70kDa protein 1A 1.30329
RGS2 regulator of G-protein signaling 2 1.30208
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.30208
SAT1 spermidine/spermine N1-acetyltransferase 1 1.29781
F2 coagulation factor II (thrombin) 1.29781
PRKCB protein kinase C, beta 1.29719
MAOB monoamine oxidase B 1.29719
S100A8 S100 calcium binding protein A8 1.29719
ADK adenosine kinase 1.29502
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.29471
PHGDH phosphoglycerate dehydrogenase 1.2944
HADH hydroxyacyl-CoA dehydrogenase 1.2944
EPO erythropoietin 1.29256
THBS1 thrombospondin 1 1.29011
PTK2 protein tyrosine kinase 2 1.29011
NQO1 NAD(P)H dehydrogenase, quinone 1 1.29011
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.28765
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.28672
BID BH3 interacting domain death agonist 1.28518
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.28364
CALB1 calbindin 1, 28kDa 1.2818
ASIC2 acid sensing (proton gated) ion channel 2 1.2818
CCL3 chemokine (C-C motif) ligand 3 1.27936
ADRA1B adrenoceptor alpha 1B 1.27626
MAP2K2 mitogen-activated protein kinase kinase 2 1.27626
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.27316
DHCR24 24-dehydrocholesterol reductase 1.27316
TSPO translocator protein (18kDa) 1.27009
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.26732
DIABLO diablo, IAP-binding mitochondrial protein 1.26452
S100A4 S100 calcium binding protein A4 1.26144
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.26144
IL12B interleukin 12B 1.25929
COL3A1 collagen, type III, alpha 1 1.25899
PDE4B phosphodiesterase 4B, cAMP-specific 1.25868
NEFH neurofilament, heavy polypeptide 1.25868
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.25807
HOMER1 homer scaffolding protein 1 1.25745
INSIG1 insulin induced gene 1 1.25682
IL1RN interleukin 1 receptor antagonist 1.25682
CTGF connective tissue growth factor 1.25369
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.24812
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.24718
TOP2A topoisomerase (DNA) II alpha 170kDa 1.24528
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.24528
NCF1 neutrophil cytosolic factor 1 1.24401
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.24213
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.23962
EGLN3 egl-9 family hypoxia-inducible factor 3 1.23837
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.23837
VCAN versican 1.23456
E2F1 E2F transcription factor 1 1.23392
RRAS related RAS viral (r-ras) oncogene homolog 1.23392
IL12A interleukin 12A 1.23392
TAGLN3 transgelin 3 1.2336
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.23137
CDK1 cyclin-dependent kinase 1 1.23106
CTSB cathepsin B 1.22979
CYB5A cytochrome b5 type A (microsomal) 1.22884
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.2279
HRAS Harvey rat sarcoma viral oncogene homolog 1.22758
POU5F1 POU class 5 homeobox 1 1.22727
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.22632
TK1 thymidine kinase 1, soluble 1.22371
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.22371
ACTB actin, beta 1.22371
CD40LG CD40 ligand 1.22371
ACTA1 actin, alpha 1, skeletal muscle 1.22371
TAGLN transgelin 1.22371
C3 complement component 3 1.21984
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.21759
TYMP thymidine phosphorylase 1.21663
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.21337
FBN1 fibrillin 1 1.21304
GATA4 GATA binding protein 4 1.21304
ASL argininosuccinate lyase 1.21239
OPRL1 opiate receptor-like 1 1.21239
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.21239
DHFR dihydrofolate reductase 1.21076
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.21011
CTSD cathepsin D 1.20816
PRDX2 peroxiredoxin 2 1.20816
FOSL1 FOS-like antigen 1 1.20622
IGFBP5 insulin-like growth factor binding protein 5 1.2059
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.2059
CDK4 cyclin-dependent kinase 4 1.20262
EFNA1 ephrin-A1 1.20262
FASN fatty acid synthase 1.20097
EDNRA endothelin receptor type A 1.20064
JUND jun D proto-oncogene 1.19835
S100A10 S100 calcium binding protein A10 1.19574
ASS1 argininosuccinate synthase 1 1.19574
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.19477
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.19246
COL4A2 collagen, type IV, alpha 2 1.19246
ARC activity-regulated cytoskeleton-associated protein 1.19246
PLAU plasminogen activator, urokinase 1.19113
CAPN2 calpain 2, (m/II) large subunit 1.18587
TAT tyrosine aminotransferase 1.18587
MME membrane metallo-endopeptidase 1.18587
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.18391
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.18293
ADRA2A adrenoceptor alpha 2A 1.18293
DPYSL2 dihydropyrimidinase-like 2 1.18293
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.18159
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.18026
FOSL2 FOS-like antigen 2 1.17959
CDC25A cell division cycle 25A 1.17959
TIMP3 TIMP metallopeptidase inhibitor 3 1.17926
DCXR dicarbonyl/L-xylulose reductase 1.17794
EZR ezrin 1.17629
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.17497
CYBA cytochrome b-245, alpha polypeptide 1.17
BIRC3 baculoviral IAP repeat containing 3 1.16967
CYBB cytochrome b-245, beta polypeptide 1.16766
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.16766
DRD2 dopamine receptor D2 1.16467
CCNG1 cyclin G1 1.16104
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.16104
ADRA1D adrenoceptor alpha 1D 1.16035
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.15933
BIRC2 baculoviral IAP repeat containing 2 1.15899
GAP43 growth associated protein 43 1.15797
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.15661
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.15526
ENO2 enolase 2 (gamma, neuronal) 1.15526
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.15458
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.15391
NFE2L2 nuclear factor, erythroid 2-like 2 1.15256
RRM2 ribonucleotide reductase M2 1.15223
ARRB2 arrestin, beta 2 1.15156
FADD Fas (TNFRSF6)-associated via death domain 1.14919
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.14747
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.14747
AOC1 amine oxidase, copper containing 1 1.14747
TMEM97 transmembrane protein 97 1.14713
NINJ1 ninjurin 1 1.14713
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.14713
GSR glutathione reductase 1.14644
UNG uracil-DNA glycosylase 1.14336
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.14302
COL5A2 collagen, type V, alpha 2 1.14302
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.14302
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.14064
MFN2 mitofusin 2 1.1403
SCG2 secretogranin II 1.1403
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.13895
CD36 CD36 molecule (thrombospondin receptor) 1.13895
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.13758
APP amyloid beta (A4) precursor protein 1.13689
H2AFX H2A histone family, member X 1.13552
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.13552
DRD1 dopamine receptor D1 1.13518
BAK1 BCL2-antagonist/killer 1 1.13518
ANGPT1 angiopoietin 1 1.13484
BAD BCL2-associated agonist of cell death 1.13415
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.13381
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.13211
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.13075
APOE apolipoprotein E 1.13075
CREM cAMP responsive element modulator 1.1294
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.1294
E2F5 E2F transcription factor 5, p130-binding 1.12771
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.12703
XDH xanthine dehydrogenase 1.12426
ALDOA aldolase A, fructose-bisphosphate 1.12391
AXL AXL receptor tyrosine kinase 1.12323
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.12288
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 1.12151
GPM6A glycoprotein M6A 1.12151
RELN reelin 1.11911
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.11911
XBP1 X-box binding protein 1 1.11877
ARG2 arginase 2 1.11843
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.11843
TFRC transferrin receptor 1.11809
ERBB2 erb-b2 receptor tyrosine kinase 2 1.11707
TRIB3 tribbles pseudokinase 3 1.11501
DPYD dihydropyrimidine dehydrogenase 1.11325
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.11325
IGFBP1 insulin-like growth factor binding protein 1 1.1129
MAPT microtubule-associated protein tau 1.11081
HMGA1 high mobility group AT-hook 1 1.10769
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.10734
CPT1A carnitine palmitoyltransferase 1A (liver) 1.10527
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.10527
CXCL2 chemokine (C-X-C motif) ligand 2 1.10388
PLP1 proteolipid protein 1 1.10388
ECI1 enoyl-CoA delta isomerase 1 1.10033
FGFR1 fibroblast growth factor receptor 1 1.09998
COCH cochlin 1.09786
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.09786
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.09786
CCNE2 cyclin E2 1.09751
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.09751
EGR3 early growth response 3 1.09681
LAMC2 laminin, gamma 2 1.09681
FABP4 fatty acid binding protein 4, adipocyte 1.09541
ACE angiotensin I converting enzyme 1.09541
CASP12 caspase 12 (gene/pseudogene) 1.09506
VCL vinculin 1.09332
SYN2 synapsin II 1.09262
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.09226
AKR1C3 aldo-keto reductase family 1, member C3 1.09154
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.09011
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.08975
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.08975
AKAP12 A kinase (PRKA) anchor protein 12 1.08975
HSPB1 heat shock 27kDa protein 1 1.08904
ADRA2C adrenoceptor alpha 2C 1.0869
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.08619
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.08619
COL1A2 collagen, type I, alpha 2 1.08584
FOLR1 folate receptor 1 (adult) 1.08266
PKP2 plakophilin 2 1.08161
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.08126
KLF6 Kruppel-like factor 6 1.08019
ISG15 ISG15 ubiquitin-like modifier 1.07911
S100A9 S100 calcium binding protein A9 1.07768
PCOLCE procollagen C-endopeptidase enhancer 1.07625
LMO7 LIM domain 7 1.07625
COL18A1 collagen, type XVIII, alpha 1 1.07589
ACTA2 actin, alpha 2, smooth muscle, aorta 1.07589
CREBBP CREB binding protein 1.07518
CES2 carboxylesterase 2 1.07305
SST somatostatin 1.07269
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.07128
TCF4 transcription factor 4 1.06917
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.06917
HDC histidine decarboxylase 1.06917
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.06808
CTTN cortactin 1.06588
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.06588
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.06588
ELK1 ELK1, member of ETS oncogene family 1.06588
CALR calreticulin 1.06333
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.06261
MAPK13 mitogen-activated protein kinase 13 1.0608
EIF3A eukaryotic translation initiation factor 3, subunit A 1.0608
CD4 CD4 molecule 1.0608
TACR1 tachykinin receptor 1 1.05936
LDHA lactate dehydrogenase A 1.059
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.059
EMP1 epithelial membrane protein 1 1.0561
E2F3 E2F transcription factor 3 1.05573
MXI1 MAX interactor 1, dimerization protein 1.05573
STMN1 stathmin 1 1.05423
BDKRB2 bradykinin receptor B2 1.05274
MMP7 matrix metallopeptidase 7 1.05274
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.052
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.05089
LDLR low density lipoprotein receptor 1.05015
CD9 CD9 molecule 1.04941
APAF1 apoptotic peptidase activating factor 1 1.04941
BBC3 BCL2 binding component 3 1.04721
RHOA ras homolog family member A 1.04721
IGFBP4 insulin-like growth factor binding protein 4 1.04647
ACAA2 acetyl-CoA acyltransferase 2 1.04647
ACSL6 acyl-CoA synthetase long-chain family member 6 1.04611
ETFB electron-transfer-flavoprotein, beta polypeptide 1.04611
KNG1 kininogen 1 1.04276
STAT5B signal transducer and activator of transcription 5B 1.04126
TGFA transforming growth factor, alpha 1.04051
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.04014
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.04014
TERT telomerase reverse transcriptase 1.03827
CKS2 CDC28 protein kinase regulatory subunit 2 1.03678
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.03678
RBPMS RNA binding protein with multiple splicing 1.03641
FAM129A family with sequence similarity 129, member A 1.03641
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.03641
COX5B cytochrome c oxidase subunit Vb 1.03641
ILK integrin-linked kinase 1.03197
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.03197
SPON1 spondin 1, extracellular matrix protein 1.03197
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.03159
TXN thioredoxin 1.03159
GSTO1 glutathione S-transferase omega 1 1.03084
IER3 immediate early response 3 1.02971
HSPA8 heat shock 70kDa protein 8 1.02971
ECH1 enoyl CoA hydratase 1, peroxisomal 1.02783
VDAC1 voltage-dependent anion channel 1 1.02783
IRS1 insulin receptor substrate 1 1.02746
ANGPTL4 angiopoietin-like 4 1.02746
BGN biglycan 1.02746
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.02746
PDYN prodynorphin 1.02485
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.02485
PSAT1 phosphoserine aminotransferase 1 1.02485
ANXA1 annexin A1 1.02299
CCNB2 cyclin B2 1.02299
PVALB parvalbumin 1.02299
IRF9 interferon regulatory factor 9 1.02299
ADORA3 adenosine A3 receptor 1.02299
EPOR erythropoietin receptor 1.02262
JAK1 Janus kinase 1 1.02188
IL18 interleukin 18 1.02003
EFNB3 ephrin-B3 1.01966
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.01852
TMSB4X thymosin beta 4, X-linked 1.01814
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.01625
KRT19 keratin 19, type I 1.01625
ACO2 aconitase 2, mitochondrial 1.01625
TLR4 toll-like receptor 4 1.01512
RYR2 ryanodine receptor 2 (cardiac) 1.01437
E2F2 E2F transcription factor 2 1.01399
TPI1 triosephosphate isomerase 1 1.01324
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.01249
STAT1 signal transducer and activator of transcription 1, 91kDa 1.01212
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.01062
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.01062