Chiasma Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over. (Gene Ontology, GO_0005712)
External Link http://amigo.geneontology.org/amigo/term/GO:0005712
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Genes

767 proteins co-occuring with the Chiasma cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SPO11 SPO11 meiotic protein covalently bound to DSB 3.008
RNF212 ring finger protein 212 2.822
MSH4 mutS homolog 4 2.784
REC8 REC8 meiotic recombination protein 2.708
CNTD1 cyclin N-terminal domain containing 1 2.703
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 2.65
POMC proopiomelanocortin 2.55
PRL prolactin 2.547
MSH5 mutS homolog 5 2.544
SYCP3 synaptonemal complex protein 3 2.495
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.42
SYCP1 synaptonemal complex protein 1 2.415
SMC1B structural maintenance of chromosomes 1B 2.4
MUS81 MUS81 structure-specific endonuclease subunit 2.386
MOG myelin oligodendrocyte glycoprotein 2.361
MLH1 mutL homolog 1 2.328
FANCM Fanconi anemia, complementation group M 2.253
SLC38A8 solute carrier family 38, member 8 2.244
PRDM9 PR domain containing 9 2.233
HORMAD1 HORMA domain containing 1 2.205
RAD51 RAD51 recombinase 2.189
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.158
MLH3 mutL homolog 3 2.155
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 2.135
SHOC1 shortage in chiasmata 1 2.119
STAG3 stromal antigen 3 2.111
IGF1 insulin-like growth factor 1 (somatomedin C) 2.11
SMC3 structural maintenance of chromosomes 3 2.098
TEX11 testis expressed 11 2.097
RAD21L1 RAD21-like 1 (S. pombe) 2.088
RAD21 RAD21 homolog (S. pombe) 2.071
NF1 neurofibromin 1 2.063
REC114 REC114 meiotic recombination protein 2.014
HORMAD2 HORMA domain containing 2 1.991
PDS5A PDS5 cohesin associated factor A 1.968
OTP orthopedia homeobox 1.966
SST somatostatin 1.948
SYCE1 synaptonemal complex central element protein 1 1.921
EME1 essential meiotic structure-specific endonuclease 1 1.891
VAX1 ventral anterior homeobox 1 1.874
ADARB1 adenosine deaminase, RNA-specific, B1 1.863
MEI4 meiosis-specific 4 homolog (S. cerevisiae) 1.848
OPN4 opsin 4 1.846
IHO1 interactor of HORMAD1 1 1.82
TEX12 testis expressed 12 1.798
SGO2 shugoshin 2 1.781
NLRP3 NLR family, pyrin domain containing 3 1.774
TBX19 T-box 19 1.76
MEN1 multiple endocrine neoplasia I 1.747
RAD50 RAD50 homolog (S. cerevisiae) 1.71
ANKRD31 ankyrin repeat domain 31 1.709
AURKB aurora kinase B 1.707
FBF1 Fas (TNFRSF6) binding factor 1 1.69
HID1 HID1 domain containing 1.677
RNF212B ring finger protein 212B 1.676
GPR143 G protein-coupled receptor 143 1.676
AURKAIP1 aurora kinase A interacting protein 1 1.661
RECQL4 RecQ protein-like 4 1.657
PXDNL peroxidasin-like 1.657
PXDN peroxidasin 1.653
OXT oxytocin/neurophysin I prepropeptide 1.644
WAPL WAPL cohesin release factor 1.643
CENPA centromere protein A 1.641
INS insulin 1.634
RREB1 ras responsive element binding protein 1 1.629
SYCE2 synaptonemal complex central element protein 2 1.625
SUN1 Sad1 and UNC84 domain containing 1 1.621
RMI1 RecQ mediated genome instability 1 1.619
PMEPA1 prostate transmembrane protein, androgen induced 1 1.617
HESX1 HESX homeobox 1 1.613
SKIC8 SKI8 subunit of superkiller complex 1.608
OTX2 orthodenticle homeobox 2 1.574
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.573
H1-6 H1.6 linker histone, cluster member 1.572
SMC1A structural maintenance of chromosomes 1A 1.569
MEIKIN meiotic kinetochore factor 1.561
GFAP glial fibrillary acidic protein 1.559
NKX2-1 NK2 homeobox 1 1.555
SIX6 SIX homeobox 6 1.551
GHRH growth hormone releasing hormone 1.547
TRIP13 thyroid hormone receptor interactor 13 1.542
SYCP2 synaptonemal complex protein 2 1.541
UNC119 unc-119 homolog (C. elegans) 1.532
SLX4 SLX4 structure-specific endonuclease subunit 1.527
PAX6 paired box 6 1.522
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.517
MSH3 mutS homolog 3 1.517
SGO1 shugoshin 1 1.514
NCAPD3 non-SMC condensin II complex, subunit D3 1.512
TRH thyrotropin-releasing hormone 1.512
H3-3B H3.3 histone B 1.51
KIAA1549 KIAA1549 1.504
BMP7 bone morphogenetic protein 7 1.503
ATM ATM serine/threonine kinase 1.499
GHR growth hormone receptor 1.496
BLM Bloom syndrome, RecQ helicase-like 1.488
H3-5 H3.5 histone 1.484
H3C7 H3 clustered histone 7 1.482
H3-7 H3.7 histone (putative) 1.478
H3C13 H3 clustered histone 13 1.478
H3-4 H3.4 histone, cluster member 1.477
CRH corticotropin releasing hormone 1.476
MEI1 meiosis inhibitor 1 1.473
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.472
FIGNL1 fidgetin-like 1 1.461
FOXB1 forkhead box B1 1.459
NIPBL Nipped-B homolog (Drosophila) 1.453
H2AX H2A.X variant histone 1.448
TOP3A topoisomerase (DNA) III alpha 1.447
GEN1 GEN1 Holliday junction 5' flap endonuclease 1.444
OLIG2 oligodendrocyte lineage transcription factor 2 1.436
NPY neuropeptide Y 1.434
EXO1 exonuclease 1 1.417
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 1.412
RBBP8 retinoblastoma binding protein 8 1.41
SYP synaptophysin 1.409
PRR19 proline rich 19 1.408
CENPS-CORT CENPS-CORT readthrough 1.402
SIM1 single-minded family bHLH transcription factor 1 1.402
PPIE peptidylprolyl isomerase E (cyclophilin E) 1.398
GPR101 G protein-coupled receptor 101 1.398
DNTT DNA nucleotidylexotransferase 1.395
SMC5 structural maintenance of chromosomes 5 1.395
SFTPA2 surfactant protein A2 1.389
SFTPA1 surfactant protein A1 1.386
FRMD7 FERM domain containing 7 1.377
SSTR5 somatostatin receptor 5 1.375
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1.374
CDCA5 cell division cycle associated 5 1.373
KISS1 KiSS-1 metastasis-suppressor 1.367
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 1.361
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.353
SIX3 SIX homeobox 3 1.348
ISL1 ISL LIM homeobox 1 1.344
CHEK2 checkpoint kinase 2 1.343
POTEF POTE ankyrin domain family, member F 1.332
PLK2 polo-like kinase 2 1.33
CD68 CD68 molecule 1.325
NKX2-2 NK2 homeobox 2 1.324
SHH sonic hedgehog 1.32
CD151 CD151 molecule (Raph blood group) 1.32
SMC6 structural maintenance of chromosomes 6 1.317
RAD51C RAD51 paralog C 1.314
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 1.307
AGRP agouti related neuropeptide 1.302
AIF1 allograft inflammatory factor 1 1.293
RPRML reprimo-like 1.288
PER2 period circadian clock 2 1.287
CDK2 cyclin-dependent kinase 2 1.286
TIGD1 tigger transposable element derived 1 1.284
SYCE3 synaptonemal complex central element protein 3 1.282
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.275
PTTG1 pituitary tumor-transforming 1 1.274
FOS FBJ murine osteosarcoma viral oncogene homolog 1.266
TP53 tumor protein p53 1.262
BMAL1 basic helix-loop-helix ARNT like 1 1.259
GHRL ghrelin/obestatin prepropeptide 1.257
RTEL1 regulator of telomere elongation helicase 1 1.243
PDS5B PDS5 cohesin associated factor B 1.243
CETN3 centrin, EF-hand protein, 3 1.24
GH1 growth hormone 1 1.237
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.235
HCRT hypocretin (orexin) neuropeptide precursor 1.233
OSCAR osteoclast associated, immunoglobulin-like receptor 1.232
POU4F1 POU class 4 homeobox 1 1.228
NKX1-1 NK1 homeobox 1 1.228
MGMT O-6-methylguanine-DNA methyltransferase 1.228
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 1.227
CARTPT CART prepropeptide 1.224
HMX3 H6 family homeobox 3 1.224
MSH2 mutS homolog 2 1.223
MEIOB meiosis specific with OB domains 1.221
LGALS4 lectin, galactoside-binding, soluble, 4 1.217
PTTG2 pituitary tumor-transforming 2 1.212
SPATA22 spermatogenesis associated 22 1.21
MSH6 mutS homolog 6 1.206
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 1.199
BDNF brain-derived neurotrophic factor 1.197
BRCA1 breast cancer 1, early onset 1.191
CSRP1 cysteine and glycine-rich protein 1 1.191
BRCA2 breast cancer 2, early onset 1.187
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.181
FSHB follicle stimulating hormone, beta polypeptide 1.178
ACE angiotensin I converting enzyme 1.175
CETN2 centrin, EF-hand protein, 2 1.174
TH tyrosine hydroxylase 1.172
KCTD19 potassium channel tetramerization domain containing 19 1.172
PMCH pro-melanin-concentrating hormone 1.171
SH2D3C SH2 domain containing 3C 1.168
LHX9 LIM homeobox 9 1.166
TEX15 testis expressed 15 1.16
CDC7 cell division cycle 7 1.16
GCG glucagon 1.159
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 1.159
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 1.155
CALB2 calbindin 2 1.151
DBF4 DBF4 zinc finger 1.151
SOX3 SRY (sex determining region Y)-box 3 1.149
SSTR2 somatostatin receptor 2 1.149
ESX1 ESX homeobox 1 1.148
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.147
CDC5L cell division cycle 5-like 1.147
NEFL neurofilament, light polypeptide 1.142
AGO4 argonaute RISC catalytic component 4 1.133
LEP leptin 1.133
OCA2 oculocutaneous albinism II 1.131
KISS1R KISS1 receptor 1.13
TAC3 tachykinin 3 1.129
SOX10 SRY (sex determining region Y)-box 10 1.126
LIG4 ligase IV, DNA, ATP-dependent 1.123
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 1.119
PER3 period circadian clock 3 1.118
NF2 neurofibromin 2 (merlin) 1.116
CNTF ciliary neurotrophic factor 1.113
IL6 interleukin 6 1.113
GH2 growth hormone 2 1.109
CCNDBP1 cyclin D-type binding-protein 1 1.106
NKX1-2 NK1 homeobox 2 1.102
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.099
TYR tyrosinase 1.099
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.099
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.099
IL1B interleukin 1, beta 1.098
NTN1 netrin 1 1.091
TRIM26 tripartite motif containing 26 1.09
MCM9 minichromosome maintenance complex component 9 1.086
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.084
H2BC21 H2B clustered histone 21 1.083
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.078
SLC45A2 solute carrier family 45, member 2 1.077
ZIM2 zinc finger, imprinted 2 1.076
H2AC20 H2A clustered histone 20 1.074
H2AC19 H2A clustered histone 19 1.073
RPA3 replication protein A3, 14kDa 1.069
SPIDR scaffolding protein involved in DNA repair 1.067
USP26 ubiquitin specific peptidase 26 1.066
CLOCK clock circadian regulator 1.061
PDYN prodynorphin 1.058
CSH2 chorionic somatomammotropin hormone 2 1.058
ESR1 estrogen receptor 1 1.054
GCNA germ cell nuclear acidic peptidase 1.053
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.053
GNRHR gonadotropin-releasing hormone receptor 1.049
CD1E CD1e molecule 1.047
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.042
KANSL1 KAT8 regulatory NSL complex subunit 1 1.04
MYRF myelin regulatory factor 1.036
FOXG1 forkhead box G1 1.036
DPYSL5 dihydropyrimidinase-like 5 1.032
MPO myeloperoxidase 1.032
ACOT7 acyl-CoA thioesterase 7 1.028
IGFBP3 insulin-like growth factor binding protein 3 1.028
UBXN11 UBX domain protein 11 1.026
CD1B CD1b molecule 1.025
RAX retina and anterior neural fold homeobox 1.02
FGF8 fibroblast growth factor 8 (androgen-induced) 1.018
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.016
CD34 CD34 molecule 1.016
FTL ferritin, light polypeptide 1.011
TERB1 telomere repeat binding bouquet formation protein 1 1.011
CLEC3B C-type lectin domain family 3, member B 1.011
RAD51B RAD51 paralog B 1.01
STRA8 stimulated by retinoic acid 8 1.008
FOXD1 forkhead box D1 1.008
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.007
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 1.007
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.005
PLK1 polo-like kinase 1 1.005
ERCC1 excision repair cross-complementation group 1 1.004
PGR progesterone receptor 1.003
INCENP inner centromere protein antigens 135/155kDa 1.003
KATNIP katanin interacting protein 1.002
AURKC aurora kinase C 1.001
ZIM3 zinc finger, imprinted 3 0.998
NCAPH non-SMC condensin I complex, subunit H 0.996
ENO2 enolase 2 (gamma, neuronal) 0.994
RECQL RecQ helicase-like 0.994
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.993
CD1D CD1d molecule 0.99
FIGN fidgetin 0.989
TNF tumor necrosis factor 0.988
MCM8 minichromosome maintenance complex component 8 0.987
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.974
GLP1R glucagon-like peptide 1 receptor 0.972
NCAPG2 non-SMC condensin II complex, subunit G2 0.971
CRY2 cryptochrome circadian clock 2 0.97
TG thyroglobulin 0.968
GPR151 G protein-coupled receptor 151 0.962
CRY1 cryptochrome circadian clock 1 0.959
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.959
GPR139 G protein-coupled receptor 139 0.951
MAU2 MAU2 sister chromatid cohesion factor 0.947
ZMYND15 zinc finger, MYND-type containing 15 0.945
LRMDA leucine rich melanocyte differentiation associated 0.944
CLDN5 claudin 5 0.944
FYCO1 FYVE and coiled-coil domain containing 1 0.942
CD1C CD1c molecule 0.939
STAG2 stromal antigen 2 0.936
IGSF1 immunoglobulin superfamily, member 1 0.934
PVALB parvalbumin 0.932
PRTN3 proteinase 3 0.931
PCNA proliferating cell nuclear antigen 0.93
PAX2 paired box 2 0.93
SMC4 structural maintenance of chromosomes 4 0.928
TACR3 tachykinin receptor 3 0.928
CAMKMT calmodulin-lysine N-methyltransferase 0.925
H2BK1 H2B.K variant histone 1 0.921
H2BW1 H2B.W histone 1 0.919
H2BC12L H2B clustered histone 12 like 0.919
H2BW2 H2B.W histone 2 0.919
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.917
H2BC13 H2B clustered histone 13 0.917
H2BC18 H2B clustered histone 18 0.916
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 0.916
H2BC14 H2B clustered histone 14 0.915
H2BC17 H2B clustered histone 17 0.915
H2BC26 H2B clustered histone 26 0.915
H2BC9 H2B clustered histone 9 0.915
DNAH8 dynein, axonemal, heavy chain 8 0.915
HASPIN histone H3 associated protein kinase 0.914
GNAS GNAS complex locus 0.913
TYRP1 tyrosinase-related protein 1 0.912
GGNBP2 gametogenetin binding protein 2 0.912
H2BC15 H2B clustered histone 15 0.911
H2BC3 H2B clustered histone 3 0.91
H2BC11 H2B clustered histone 11 0.909
AURKA aurora kinase A 0.908
NGF nerve growth factor (beta polypeptide) 0.907
AQP9 aquaporin 9 0.906
H2BC12 H2B clustered histone 12 0.906
HSF2BP heat shock transcription factor 2 binding protein 0.905
TRHR thyrotropin-releasing hormone receptor 0.904
SYN3 synapsin III 0.901
LHX6 LIM homeobox 6 0.9
FANCD2 Fanconi anemia, complementation group D2 0.9
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.9
H2BC1 H2B clustered histone 1 0.899
H2BC4 H2B clustered histone 4 0.899
DRD2 dopamine receptor D2 0.896
H2BC5 H2B clustered histone 5 0.895
TOP2A topoisomerase (DNA) II alpha 170kDa 0.895
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.891
CDK1 cyclin-dependent kinase 1 0.89
PECAM1 platelet/endothelial cell adhesion molecule 1 0.889
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 0.888
SYN2 synapsin II 0.88
PIWIL4 piwi-like RNA-mediated gene silencing 4 0.877
MAP2K1 mitogen-activated protein kinase kinase 1 0.876
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.875
SSTR1 somatostatin receptor 1 0.874
NPTX2 neuronal pentraxin II 0.873
THRB thyroid hormone receptor, beta 0.871
ATOH7 atonal homolog 7 (Drosophila) 0.87
CD8A CD8a molecule 0.868
SFR1 SWI5-dependent recombination repair 1 0.867
USP8 ubiquitin specific peptidase 8 0.867
TAC1 tachykinin, precursor 1 0.866
LHX4 LIM homeobox 4 0.866
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.865
GAP43 growth associated protein 43 0.863
SNED1 sushi, nidogen and EGF-like domains 1 0.862
NKX6-2 NK6 homeobox 2 0.861
CALB1 calbindin 1, 28kDa 0.859
NANOS2 nanos homolog 2 (Drosophila) 0.858
GJB6 gap junction protein, beta 6, 30kDa 0.855
TSHB thyroid stimulating hormone, beta 0.853
LHX5 LIM homeobox 5 0.853
RNF7 ring finger protein 7 0.853
NES nestin 0.852
H2AZ1 H2A.Z variant histone 1 0.851
PRDM16 PR domain containing 16 0.851
GBX2 gastrulation brain homeobox 2 0.845
CCNL2 cyclin L2 0.845
RMI2 RecQ mediated genome instability 2 0.844
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.844
OR2J2 olfactory receptor, family 2, subfamily J, member 2 0.844
ALLC allantoicase 0.843
POU1F1 POU class 1 homeobox 1 0.842
AANAT aralkylamine N-acetyltransferase 0.842
KIF2C kinesin family member 2C 0.841
RAD9A RAD9 homolog A (S. pombe) 0.841
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 0.839
SYN1 synapsin I 0.836
ZGLP1 zinc finger, GATA-like protein 1 0.833
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.832
MEIOSIN meiosis initiator 0.831
STH saitohin 0.829
RAD52 RAD52 homolog (S. cerevisiae) 0.829
PRLHR prolactin releasing hormone receptor 0.829
ZER1 zyg-11 related, cell cycle regulator 0.828
POU4F2 POU class 4 homeobox 2 0.825
ARHGAP9 Rho GTPase activating protein 9 0.823
GLI1 GLI family zinc finger 1 0.822
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.821
RAD18 RAD18 E3 ubiquitin protein ligase 0.821
HUS1 HUS1 checkpoint homolog (S. pombe) 0.82
OR14J1 olfactory receptor, family 14, subfamily J, member 1 0.82
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 0.82
RBL2 retinoblastoma-like 2 0.819
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.817
GHRHR growth hormone releasing hormone receptor 0.817
SLC44A3 solute carrier family 44, member 3 0.817
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.816
TIMELESS timeless circadian clock 0.816
CD274 CD274 molecule 0.815
VCF2 VCP nuclear cofactor family member 2 0.814
PRLH prolactin releasing hormone 0.813
EMX2 empty spiracles homeobox 2 0.812
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 0.809
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.808
CDC20 cell division cycle 20 0.807
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.807
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.806
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.806
OCLN occludin 0.804
SRY sex determining region Y 0.803
ITK IL2-inducible T-cell kinase 0.801
RECQL5 RecQ protein-like 5 0.801
NPPC natriuretic peptide C 0.8
CHGA chromogranin A 0.798
CD207 CD207 molecule, langerin 0.798
VSX2 visual system homeobox 2 0.798
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.797
MDC1 mediator of DNA-damage checkpoint 1 0.796
RHOD ras homolog family member D 0.795
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.794
ESR2 estrogen receptor 2 (ER beta) 0.794
IFT81 intraflagellar transport 81 0.792
GALC galactosylceramidase 0.791
ARTN artemin 0.791
NEUROG1 neurogenin 1 0.789
OXTR oxytocin receptor 0.787
HELB helicase (DNA) B 0.786
PLAGL1 pleiomorphic adenoma gene-like 1 0.786
SWI5 SWI5 recombination repair homolog (yeast) 0.786
CARD16 caspase recruitment domain family, member 16 0.785
PROK2 prokineticin 2 0.784
ZNF98 zinc finger protein 98 0.784
KIF4A kinesin family member 4A 0.779
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.778
CFLAR CASP8 and FADD-like apoptosis regulator 0.777
PAX4 paired box 4 0.777
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.774
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.773
CRHR1 corticotropin releasing hormone receptor 1 0.773
TJP1 tight junction protein 1 0.771
SPRTN SprT-like N-terminal domain 0.768
AMH anti-Mullerian hormone 0.767
WFS1 Wolfram syndrome 1 (wolframin) 0.766
SOX2 SRY (sex determining region Y)-box 2 0.766
WNT8B wingless-type MMTV integration site family, member 8B 0.766
BCL2 B-cell CLL/lymphoma 2 0.764
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.764
GALP galanin-like peptide 0.76
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.759
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.758
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.758
GPSM3 G-protein signaling modulator 3 0.758
AGGF1 angiogenic factor with G patch and FHA domains 1 0.758
LMX1A LIM homeobox transcription factor 1, alpha 0.757
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.756
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.754
KLK6 kallikrein-related peptidase 6 0.754
NLN neurolysin (metallopeptidase M3 family) 0.753
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.753
LHX1 LIM homeobox 1 0.752
PHGDH phosphoglycerate dehydrogenase 0.751
MAPK3 mitogen-activated protein kinase 3 0.75
POU3F3 POU class 3 homeobox 3 0.749
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.749
NBAS neuroblastoma amplified sequence 0.748
SPATA16 spermatogenesis associated 16 0.747
SETD1A SET domain containing 1A 0.746
LPA lipoprotein, Lp(a) 0.745
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.744
HELQ helicase, POLQ-like 0.741
TBR1 T-box, brain, 1 0.74
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.74
ERCC4 excision repair cross-complementation group 4 0.737
AVPR2 arginine vasopressin receptor 2 0.736
FGFR1 fibroblast growth factor receptor 1 0.734
PDZD4 PDZ domain containing 4 0.734
IGLL5 immunoglobulin lambda-like polypeptide 5 0.734
LMX1B LIM homeobox transcription factor 1, beta 0.734
CENPC centromere protein C 0.732
LHB luteinizing hormone beta polypeptide 0.73
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.73
SIM2 single-minded family bHLH transcription factor 2 0.73
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.729
NPVF neuropeptide VF precursor 0.727
CETN1 centrin, EF-hand protein, 1 0.727
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 0.727
CDKN2A cyclin-dependent kinase inhibitor 2A 0.726
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.726
GDF9 growth differentiation factor 9 0.725
HPS5 Hermansky-Pudlak syndrome 5 0.724
FGF13 fibroblast growth factor 13 0.723
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.722
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.721
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.72
DRAXIN dorsal inhibitory axon guidance protein 0.72
SP8 Sp8 transcription factor 0.717
NPAS2 neuronal PAS domain protein 2 0.714
PRSS3 protease, serine, 3 0.713
ZIC2 Zic family member 2 0.713
HPS6 Hermansky-Pudlak syndrome 6 0.708
CD4 CD4 molecule 0.706
RPA4 replication protein A4, 30kDa 0.706
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.705
TPO thyroid peroxidase 0.705
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.704
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.704
AGO1 argonaute RISC catalytic component 1 0.702
NDC80 NDC80 kinetochore complex component 0.702
ASCL1 achaete-scute family bHLH transcription factor 1 0.7
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.7
DENND2B DENN domain containing 2B 0.699
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.698
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.697
EDNRB endothelin receptor type B 0.697
RSC1A1 regulatory solute carrier protein, family 1, member 1 0.696
INA internexin neuronal intermediate filament protein, alpha 0.696
TNS3 tensin 3 0.696
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 0.693
NCAPD2 non-SMC condensin I complex, subunit D2 0.693
TBC1D20 TBC1 domain family, member 20 0.691
IFNB1 interferon, beta 1, fibroblast 0.691
ACAA1 acetyl-CoA acyltransferase 1 0.69
BIN2 bridging integrator 2 0.689
DLX5 distal-less homeobox 5 0.688
L1CAM L1 cell adhesion molecule 0.687
CD59 CD59 molecule, complement regulatory protein 0.686
CTCF CCCTC-binding factor (zinc finger protein) 0.685
NTS neurotensin 0.684
BIN3 bridging integrator 3 0.681
POLM polymerase (DNA directed), mu 0.68
EGFR epidermal growth factor receptor 0.68
KLHL10 kelch-like family member 10 0.68
AREG amphiregulin 0.679
ZNF431 zinc finger protein 431 0.677
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.677
RANBP3 RAN binding protein 3 0.672
PTRH2 peptidyl-tRNA hydrolase 2 0.672
LHX3 LIM homeobox 3 0.672
CSF3 colony stimulating factor 3 (granulocyte) 0.671
LINGO1 leucine rich repeat and Ig domain containing 1 0.67
PNMA2 paraneoplastic Ma antigen 2 0.67
GJC2 gap junction protein, gamma 2, 47kDa 0.669
PTPRC protein tyrosine phosphatase, receptor type, C 0.669
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.668
CNTNAP2 contactin associated protein-like 2 0.667
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.665
H2AZ2 H2A.Z variant histone 2 0.665
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.664
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.663
TEDDM1 transmembrane epididymal protein 1 0.66
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.659
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.659
CCNB1 cyclin B1 0.656
TGFB1 transforming growth factor, beta 1 0.656
C4BPA complement component 4 binding protein, alpha 0.655
SNX3 sorting nexin 3 0.655
BCAS1 breast carcinoma amplified sequence 1 0.654
APP amyloid beta (A4) precursor protein 0.653
S100B S100 calcium binding protein B 0.65
DCAF17 DDB1 and CUL4 associated factor 17 0.65
IL10 interleukin 10 0.649
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.648
FGF10 fibroblast growth factor 10 0.648
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.647
RAD17 RAD17 homolog (S. pombe) 0.647
GNS glucosamine (N-acetyl)-6-sulfatase 0.647
DLK1 delta-like 1 homolog (Drosophila) 0.643
NCAM1 neural cell adhesion molecule 1 0.643
KRT7 keratin 7, type II 0.642
NANOS1 nanos homolog 1 (Drosophila) 0.642
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 0.641
RAD51D RAD51 paralog D 0.639
SYCE1L synaptonemal complex central element protein 1-like 0.639
FGF17 fibroblast growth factor 17 0.638
LRRIQ3 leucine-rich repeats and IQ motif containing 3 0.638
ALPP alkaline phosphatase, placental 0.638
CLSTN1 calsyntenin 1 0.637
OTOR otoraplin 0.637
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.637
ANKLE1 ankyrin repeat and LEM domain containing 1 0.635
MAB21L4 mab-21 like 4 0.635
VIPR2 vasoactive intestinal peptide receptor 2 0.633
SHBG sex hormone-binding globulin 0.632
UNC79 unc-79 homolog (C. elegans) 0.631
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.631
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.63
CENPX centromere protein X 0.63
PLPPR3 phospholipid phosphatase related 3 0.627
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.626
AGK acylglycerol kinase 0.626
TOPBP1 topoisomerase (DNA) II binding protein 1 0.625
PCGF3 polycomb group ring finger 3 0.624
UNC5A unc-5 homolog A (C. elegans) 0.624
PLP1 proteolipid protein 1 0.621
EDRF1 erythroid differentiation regulatory factor 1 0.619
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.617
PDIK1L PDLIM1 interacting kinase 1 like 0.617
CDCA8 cell division cycle associated 8 0.615
ZNF718 zinc finger protein 718 0.614
DCPS decapping enzyme, scavenger 0.613
HR hair growth associated 0.611
ZPR1 ZPR1 zinc finger 0.609
USP9Y ubiquitin specific peptidase 9, Y-linked 0.609
CHMP2A charged multivesicular body protein 2A 0.608
TFG TRK-fused gene 0.607
TUB tubby bipartite transcription factor 0.606
SPMAP2 sperm microtubule associated protein 2 0.604
AGXT alanine-glyoxylate aminotransferase 0.604
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.601
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.599
FERMT1 fermitin family member 1 0.598
NTSR1 neurotensin receptor 1 (high affinity) 0.595
NECTIN1 nectin cell adhesion molecule 1 0.594
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.594
CREB1 cAMP responsive element binding protein 1 0.594
H4C15 H4 clustered histone 15 0.594
PRCP prolylcarboxypeptidase (angiotensinase C) 0.594
ARHGAP29 Rho GTPase activating protein 29 0.593
SLC25A46 solute carrier family 25, member 46 0.593
SIX1 SIX homeobox 1 0.592
RTN4R reticulon 4 receptor 0.592
SIRT1 sirtuin 1 0.592
DAZL deleted in azoospermia-like 0.591
ZNF438 zinc finger protein 438 0.59
NPIPB11 nuclear pore complex interacting protein family, member B11 0.59
DBX1 developing brain homeobox 1 0.59
CHEK1 checkpoint kinase 1 0.589
FRG2C FSHD region gene 2 family, member C 0.589
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.588
TMEM11 transmembrane protein 11 0.588
SIRT2 sirtuin 2 0.587
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.587
MRS2 MRS2 magnesium transporter 0.586
FHDC1 FH2 domain containing 1 0.583
PROKR2 prokineticin receptor 2 0.583
GLB1 galactosidase, beta 1 0.583
PPP4C protein phosphatase 4, catalytic subunit 0.583
DNA2 DNA replication helicase/nuclease 2 0.582
CA2 carbonic anhydrase II 0.58
KRTAP9-2 keratin associated protein 9-2 0.58
DES desmin 0.58
TBX3 T-box 3 0.579
OPN3 opsin 3 0.578
TBL1X transducin (beta)-like 1X-linked 0.577
MAPT microtubule-associated protein tau 0.575
PRM2 protamine 2 0.574
FANCG Fanconi anemia, complementation group G 0.573
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.571
TPRX1 tetra-peptide repeat homeobox 1 0.571
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.568
CDC27 cell division cycle 27 0.568
KCTD11 potassium channel tetramerization domain containing 11 0.568
FSHR follicle stimulating hormone receptor 0.568
CCL2 chemokine (C-C motif) ligand 2 0.567
NEK1 NIMA-related kinase 1 0.567
ZFYVE26 zinc finger, FYVE domain containing 26 0.566
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.566
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 0.566
PDCD1 programmed cell death 1 0.564
ZC2HC1A zinc finger, C2HC-type containing 1A 0.564
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.563
ADA adenosine deaminase 0.563
PLAT plasminogen activator, tissue 0.563
H1-0 H1.0 linker histone 0.562
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.562
PITX2 paired-like homeodomain 2 0.561
ZNF595 zinc finger protein 595 0.561
ZNHIT3 zinc finger, HIT-type containing 3 0.56
KASH5 KASH domain containing 5 0.559
CD302 CD302 molecule 0.559
CRYBB3 crystallin, beta B3 0.557
CCDC13 coiled-coil domain containing 13 0.557
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.554
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.553
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.551
TERT telomerase reverse transcriptase 0.551
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.551
WSCD1 WSC domain containing 1 0.55
MMP1 matrix metallopeptidase 1 0.549
CPLX1 complexin 1 0.549
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.548
TBX1 T-box 1 0.547
CSPG4 chondroitin sulfate proteoglycan 4 0.546
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.546
SLC26A8 solute carrier family 26 (anion exchanger), member 8 0.546
PTEN phosphatase and tensin homolog 0.546
DMRT1 doublesex and mab-3 related transcription factor 1 0.545
MEIS2 Meis homeobox 2 0.545
PROP1 PROP paired-like homeobox 1 0.545
RTRAF RNA transcription, translation and transport factor 0.544
RHOJ ras homolog family member J 0.543
EOMES eomesodermin 0.543
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like 0.542
EID3 EP300 interacting inhibitor of differentiation 3 0.541
ZMYM6 zinc finger, MYM-type 6 0.541
EPHB3 EPH receptor B3 0.54
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.539
PHC3 polyhomeotic homolog 3 (Drosophila) 0.539
CDK20 cyclin-dependent kinase 20 0.538
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.536
PLXNC1 plexin C1 0.536
CKB creatine kinase, brain 0.536
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.535
RBPMS RNA binding protein with multiple splicing 0.534
ATRIP ATR interacting protein 0.534
DPYSL2 dihydropyrimidinase-like 2 0.534
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 0.534
PLXNA4 plexin A4 0.532
MCM7 minichromosome maintenance complex component 7 0.532
NEFH neurofilament, heavy polypeptide 0.532
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.531
RCVRN recoverin 0.531
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.531
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 0.53
RBMY1D RNA binding motif protein, Y-linked, family 1, member D 0.528
VAX2 ventral anterior homeobox 2 0.527
ENO1 enolase 1, (alpha) 0.526
ANKRD36C ankyrin repeat domain 36C 0.524
APEH acylaminoacyl-peptide hydrolase 0.523
WSCD2 WSC domain containing 2 0.523
INSR insulin receptor 0.523
OLIG1 oligodendrocyte transcription factor 1 0.522
LGI1 leucine-rich, glioma inactivated 1 0.522
LVRN laeverin 0.521
FANCE Fanconi anemia, complementation group E 0.521
SDC1 syndecan 1 0.52
ZIC5 Zic family member 5 0.519
VWF von Willebrand factor 0.519
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.518
CCM2 cerebral cavernous malformation 2 0.518
GRSF1 G-rich RNA sequence binding factor 1 0.517
CATSPER1 cation channel, sperm associated 1 0.517
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.517
RNF32 ring finger protein 32 0.517
EGF epidermal growth factor 0.516
PEPD peptidase D 0.516
SSTR3 somatostatin receptor 3 0.516
FOXA1 forkhead box A1 0.513
LOC102724428 serine/threonine-protein kinase SIK1 0.512
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.511
MAJIN membrane anchored junction protein 0.511
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.51
FGF3 fibroblast growth factor 3 0.51
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 0.509
RNASE11 ribonuclease, RNase A family, 11 (non-active) 0.509
FGF7 fibroblast growth factor 7 0.509
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 0.508
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 0.506
FGF5 fibroblast growth factor 5 0.506
CCDC18 coiled-coil domain containing 18 0.505
MC4R melanocortin 4 receptor 0.504
PAGE2 P antigen family, member 2 (prostate associated) 0.504
EFNA5 ephrin-A5 0.503
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.501
RBP3 retinol binding protein 3, interstitial 0.501
ECEL1 endothelin converting enzyme-like 1 0.501
CNGA3 cyclic nucleotide gated channel alpha 3 0.501
H4C7 H4 clustered histone 7 0.501
JUN jun proto-oncogene 0.501
SMIM44 small integral membrane protein 44 0.5
FMR1 fragile X mental retardation 1 0.5