Childhood Acute Myeloid Leukemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0220621
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Genes

187 genes associated with the disease Childhood Acute Myeloid Leukemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AFDN afadin, adherens junction formation factor
ANXA2 annexin A2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASRGL1 asparaginase like 1
ASXL1 additional sex combs like transcriptional regulator 1
ASXL2 additional sex combs like transcriptional regulator 2
ATM ATM serine/threonine kinase
ATN1 atrophin 1
BAALC brain and acute leukemia, cytoplasmic
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
BRD4 bromodomain containing 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBFB core-binding factor, beta subunit
CCDC28A coiled-coil domain containing 28A
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD6 CD6 molecule
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CES2 carboxylesterase 2
CNTFR ciliary neurotrophic factor receptor
CPOX coproporphyrinogen oxidase
CREBBP CREB binding protein
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTSL cathepsin L
CXCR4 chemokine (C-X-C motif) receptor 4
CXXC5 CXXC finger protein 5
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DEK DEK proto-oncogene
DERL1 derlin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EBF3 early B-cell factor 3
EBP emopamil binding protein (sterol isomerase)
EFS embryonal Fyn-associated substrate
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4E eukaryotic translation initiation factor 4E
ELANE elastase, neutrophil expressed
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETV6 ets variant 6
FANCB Fanconi anemia, complementation group B
FAS Fas cell surface death receptor
FLT3 fms-related tyrosine kinase 3
FUS FUS RNA binding protein
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GLI1 GLI family zinc finger 1
GLIS2 GLIS family zinc finger 2
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
HDAC1 histone deacetylase 1
HOXD10 homeobox D10
HPGDS hematopoietic prostaglandin D synthase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGFBP7 insulin-like growth factor binding protein 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL17D interleukin 17D
IL2 interleukin 2
IL27 interleukin 27
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JAK2 Janus kinase 2
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LOC102724594 splicing factor U2AF 35 kDa subunit
LRP1 low density lipoprotein receptor-related protein 1
MAPK3 mitogen-activated protein kinase 3
MARCKSL1 MARCKS-like 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MECOM MDS1 and EVI1 complex locus
MEF2C myocyte enhancer factor 2C
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MME membrane metallo-endopeptidase
MN1 meningioma (disrupted in balanced translocation) 1
MNX1 motor neuron and pancreas homeobox 1
MPO myeloperoxidase
MSH3 mutS homolog 3
MT-ATP6 ATP synthase F0 subunit 6
MT-ND3 NADH dehydrogenase, subunit 3 (complex I)
MT3 metallothionein 3
MTTP microsomal triglyceride transfer protein
MVP major vault protein
MYH11 myosin, heavy chain 11, smooth muscle
NCAM1 neural cell adhesion molecule 1
NCOA2 nuclear receptor coactivator 2
NEO1 neogenin 1
NOM1 nucleolar protein with MIF4G domain 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PCBP4 poly(rC) binding protein 4
PDCD6 programmed cell death 6
PICALM phosphatidylinositol binding clathrin assembly protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB4 phospholipase C, beta 4
PML promyelocytic leukemia
PRAME preferentially expressed antigen in melanoma
PRDM16 PR domain containing 16
PSIP1 PC4 and SFRS1 interacting protein 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
RARA retinoic acid receptor, alpha
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHEBL1 Ras homolog enriched in brain like 1
RPSA ribosomal protein SA
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX3 runt-related transcription factor 3
SALL4 spalt-like transcription factor 4
SBDS Shwachman-Bodian-Diamond syndrome
SCT secretin
SEPT6 septin 6
SETBP1 SET binding protein 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SNAP91 synaptosomal-associated protein, 91kDa
SOCS2 suppressor of cytokine signaling 2
SRSF2 serine/arginine-rich splicing factor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX22 T-box 22
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TET2 tet methylcytosine dioxygenase 2
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
THPO thrombopoietin
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TP53 tumor protein p53
TRPV2 transient receptor potential cation channel, subfamily V, member 2
U2AF1 U2 small nuclear RNA auxiliary factor 1
USP10 ubiquitin specific peptidase 10
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WLS wntless Wnt ligand secretion mediator
WT1 Wilms tumor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF296 zinc finger protein 296
ZNF382 zinc finger protein 382