Childhood Burkitt Lymphoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0278879
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Genes

421 genes associated with the disease Childhood Burkitt Lymphoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AGO2 argonaute RISC catalytic component 2
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
APAF1 apoptotic peptidase activating factor 1
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
ARHGAP24 Rho GTPase activating protein 24
ARID1A AT rich interactive domain 1A (SWI-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARR3 arrestin 3, retinal (X-arrestin)
ASPG asparaginase
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B2M beta-2-microglobulin
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough
BCL6 B-cell CLL/lymphoma 6
BCL7A B-cell CLL/lymphoma 7A
BCL9 B-cell CLL/lymphoma 9
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP6 bone morphogenetic protein 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD4 bromodomain containing 4
BRD8 bromodomain containing 8
BTK Bruton agammaglobulinemia tyrosine kinase
C11ORF58 chromosome 11 open reading frame 58
C22ORF29 chromosome 22 open reading frame 29
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4B_2 complement component 4B (Chido blood group), copy 2
CA2 carbonic anhydrase II
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALCA calcitonin-related polypeptide alpha
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CCL17 chemokine (C-C motif) ligand 17
CCL20 chemokine (C-C motif) ligand 20
CCND2 cyclin D2
CCND3 cyclin D3
CCR2 chemokine (C-C motif) receptor 2
CD19 CD19 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CD6 CD6 molecule
CD69 CD69 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD81 CD81 molecule
CDC25C cell division cycle 25C
CDCA7 cell division cycle associated 7
CDCA7L cell division cycle associated 7-like
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CENPC centromere protein C
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIB1 calcium and integrin binding 1 (calmyrin)
CKS1B CDC28 protein kinase regulatory subunit 1B
CLEC4D C-type lectin domain family 4, member D
CMA1 chymase 1, mast cell
COG1 component of oligomeric golgi complex 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRYZ crystallin, zeta (quinone reductase)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
DAP death-associated protein
DCLRE1C DNA cross-link repair 1C
DDIT3 DNA-damage-inducible transcript 3
DDT D-dopachrome tautomerase
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLC1 DLC1 Rho GTPase activating protein
DLEC1 deleted in lung and esophageal cancer 1
DLL1 delta-like 1 (Drosophila)
DNER delta/notch-like EGF repeat containing
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP16 dual specificity phosphatase 16
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DUT deoxyuridine triphosphatase
DYNLL1 dynein, light chain, LC8-type 1
E2F4 E2F transcription factor 4, p107/p130-binding
E2F8 E2F transcription factor 8
EBI3 Epstein-Barr virus induced 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELN elastin
ENO1 enolase 1, (alpha)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EP300 E1A binding protein p300
EPHB2 EPH receptor B2
EPS8 epidermal growth factor receptor pathway substrate 8
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FANCB Fanconi anemia, complementation group B
FANCM Fanconi anemia, complementation group M
FAS Fas cell surface death receptor
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCRL5 Fc receptor-like 5
FGR FGR proto-oncogene, Src family tyrosine kinase
FH fumarate hydratase
FHIT fragile histidine triad
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
FOXO1 forkhead box O1
G6PD glucose-6-phosphate dehydrogenase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA2 GATA binding protein 2
GBA glucosidase, beta, acid
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GMNN geminin, DNA replication inhibitor
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPER1 G protein-coupled estrogen receptor 1
GSK3B glycogen synthase kinase 3 beta
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HMGA1 high mobility group AT-hook 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IGH immunoglobulin heavy locus
IGK immunoglobulin kappa locus
IGL immunoglobulin lambda locus
IL10 interleukin 10
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
INSR insulin receptor
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG1 jagged 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KIFAP3 kinesin-associated protein 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
KRT20 keratin 20, type I
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS9 lectin, galactoside-binding, soluble, 9
LIG4 ligase IV, DNA, ATP-dependent
LMO2 LIM domain only 2 (rhombotin-like 1)
LMO4 LIM domain only 4
LOC101060233 medium-wave-sensitive opsin 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LONP1 lon peptidase 1, mitochondrial
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MASP2 mannan-binding lectin serine peptidase 2
MAX MYC associated factor X
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MCTS1 malignant T cell amplified sequence 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIXL1 Mix paired-like homeobox
MKI67 marker of proliferation Ki-67
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MME membrane metallo-endopeptidase
MRGPRF MAS-related GPR, member F
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH3 mutS homolog 3
MST1R macrophage stimulating 1 receptor
MUM1 melanoma associated antigen (mutated) 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAAA N-acylethanolamine acid amidase
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAGLU N-acetylglucosaminidase, alpha
NBAS neuroblastoma amplified sequence
NCAM1 neural cell adhesion molecule 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLK nemo-like kinase
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NPC1 Niemann-Pick disease, type C1
NPR2 natriuretic peptide receptor 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUAK1 NUAK family, SNF1-like kinase, 1
NUCLEOLIN nucleolin multifunctional protein
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PAX5 paired box 5
PBK PDZ binding kinase
PCBP1 poly(rC) binding protein 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PHGDH phosphoglycerate dehydrogenase
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRDM1 PR domain containing 1, with ZNF domain
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRRT2 proline-rich transmembrane protein 2
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK7 protein tyrosine kinase 7 (inactive)
PTPA protein phosphatase 2 phosphatase activator
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RAB11A RAB11A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RANGAP1 Ran GTPase activating protein 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBL2 retinoblastoma-like 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RHOA ras homolog family member A
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN7A sodium channel, voltage gated, type VII alpha subunit
SDC1 syndecan 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC14L3 SEC14-like 3 (S. cerevisiae)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SENP1 SUMO1/sentrin specific peptidase 1
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SETD2 SET domain containing 2
SH2D1A SH2 domain containing 1A
SIRPA signal-regulatory protein alpha
SIRT4 sirtuin 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMAD1 SMAD family member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC3 structural maintenance of chromosomes 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOAT1 sterol O-acyltransferase 1
SOX11 SRY (sex determining region Y)-box 11
SPAG9 sperm associated antigen 9
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRM spermidine synthase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYK spleen tyrosine kinase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF3 transcription factor 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCL1A T-cell leukemia/lymphoma 1A
TCL1B T-cell leukemia/lymphoma 1B
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFE3 transcription factor binding to IGHM enhancer 3
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR9 toll-like receptor 9
TMEM132D transmembrane protein 132D
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53 tumor protein p53
TP73 tumor protein p73
TPP2 tripeptidyl peptidase II
TRAF3 TNF receptor-associated factor 3
TRD T cell receptor delta locus
TRIM13 tripartite motif containing 13
TSC1 tuberous sclerosis 1
TSG101 tumor susceptibility 101
TYK2 tyrosine kinase 2
TYRO3 TYRO3 protein tyrosine kinase
UROD uroporphyrinogen decarboxylase
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VIM vimentin
VPREB1 pre-B lymphocyte 1
VPREB3 pre-B lymphocyte 3
WDR5 WD repeat domain 5
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YY1 YY1 transcription factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3H12D zinc finger CCCH-type containing 12D
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF7 zinc finger protein 7