Childhood Kidney Wilms Tumor Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1333015
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Genes

295 genes associated with the disease Childhood Kidney Wilms Tumor in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTN4 actinin, alpha 4
AFP alpha-fetoprotein
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMER1 APC membrane recruitment protein 1
AMH anti-Mullerian hormone
APC adenomatous polyposis coli
AR androgen receptor
AREG amphiregulin
ARHGAP24 Rho GTPase activating protein 24
ASXL1 additional sex combs like transcriptional regulator 1
ATG4B autophagy related 4B, cysteine peptidase
ATN1 atrophin 1
BAALC brain and acute leukemia, cytoplasmic
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BLCAP bladder cancer associated protein
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAT catalase
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CD151 CD151 molecule (Raph blood group)
CD34 CD34 molecule
CD38 CD38 molecule
CD99 CD99 molecule
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN3 cyclin-dependent kinase inhibitor 3
CIB2 calcium and integrin binding family member 2
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CORO1A coronin, actin binding protein, 1A
CRABP2 cellular retinoic acid binding protein 2
CTCF CCCTC-binding factor (zinc finger protein)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
DES desmin
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DROSHA drosha, ribonuclease type III
E2F3 E2F transcription factor 3
EFS embryonal Fyn-associated substrate
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
ELP4 elongator acetyltransferase complex subunit 4
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
EYA1 EYA transcriptional coactivator and phosphatase 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2RL3 coagulation factor II (thrombin) receptor-like 3
FASLG Fas ligand (TNF superfamily, member 6)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEN1 flap structure-specific endonuclease 1
FGF3 fibroblast growth factor 3
FIBP fibroblast growth factor (acidic) intracellular binding protein
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FLT3 fms-related tyrosine kinase 3
FRS2 fibroblast growth factor receptor substrate 2
FSHB follicle stimulating hormone, beta polypeptide
FXR1 fragile X mental retardation, autosomal homolog 1
FZD1 frizzled class receptor 1
FZD5 frizzled class receptor 5
FZD7 frizzled class receptor 7
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GDNF glial cell derived neurotrophic factor
GLI1 GLI family zinc finger 1
GPC3 glypican 3
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HBB hemoglobin, beta
HDAC5 histone deacetylase 5
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGA2 high mobility group AT-hook 2
HNF1B HNF1 homeobox B
HNRNPL heterogeneous nuclear ribonucleoprotein L
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
INS insulin
INSR insulin receptor
INTS2 integrator complex subunit 2
IRF8 interferon regulatory factor 8
JAG1 jagged 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LIN28A lin-28 homolog A (C. elegans)
LIN28B lin-28 homolog B (C. elegans)
LMO1 LIM domain only 1 (rhombotin 1)
LMO2 LIM domain only 2 (rhombotin-like 1)
LUZP2 leucine zipper protein 2
MAPK3 mitogen-activated protein kinase 3
MBTPS1 membrane-bound transcription factor peptidase, site 1
MDK midkine (neurite growth-promoting factor 2)
MET MET proto-oncogene, receptor tyrosine kinase
MIA melanoma inhibitory activity
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLH1 mutL homolog 1
MRC1 mannose receptor, C type 1
MSH6 mutS homolog 6
MSX1 msh homeobox 1
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTTP microsomal triglyceride transfer protein
MUC16 mucin 16, cell surface associated
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAP1L4 nucleosome assembly protein 1-like 4
NCAM1 neural cell adhesion molecule 1
NCKIPSD NCK interacting protein with SH3 domain
NDC80 NDC80 kinetochore complex component
NEFL neurofilament, light polypeptide
NES nestin
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NKX6-1 NK6 homeobox 1
NNAT neuronatin
NOTCH1 notch 1
NPHP1 nephronophthisis 1 (juvenile)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OGG1 8-oxoguanine DNA glycosylase
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OSR1 odd-skipped related transciption factor 1
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PAX3 paired box 3
PAX5 paired box 5
PAX6 paired box 6
PAX8 paired box 8
PCNA proliferating cell nuclear antigen
PDGFA platelet-derived growth factor alpha polypeptide
PFN1 profilin 1
PHB prohibitin
PHF2 PHD finger protein 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHOX2B paired-like homeobox 2b
PIAS4 protein inhibitor of activated STAT, 4
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLAG1 pleiomorphic adenoma gene 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMEL premelanosome protein
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA2 patatin-like phospholipase domain containing 2
PODXL podocalyxin-like
PON1 paraoxonase 1
POU6F2 POU class 6 homeobox 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDM2 PR domain containing 2, with ZNF domain
PRKCA protein kinase C, alpha
PRM1 protamine 1
PRTN3 proteinase 3
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPA protein phosphatase 2 phosphatase activator
PTPRC protein tyrosine phosphatase, receptor type, C
QPRT quinolinate phosphoribosyltransferase
RAP1A RAP1A, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RB1 retinoblastoma 1
RBBP7 retinoblastoma binding protein 7
RBP2 retinol binding protein 2, cellular
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REN renin
REST RE1-silencing transcription factor
RET ret proto-oncogene
RIN1 Ras and Rab interactor 1
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL10 ribosomal protein L10
RRM1 ribonucleotide reductase M1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A4 S100 calcium binding protein A4
S1PR2 sphingosine-1-phosphate receptor 2
SALL1 spalt-like transcription factor 1
SALL2 spalt-like transcription factor 2
SALL4 spalt-like transcription factor 4
SAT2 spermidine/spermine N1-acetyltransferase family member 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SET SET nuclear proto-oncogene
SFRP1 secreted frizzled-related protein 1
SIX1 SIX homeobox 1
SIX2 SIX homeobox 2
SIX3 SIX homeobox 3
SLC22A18 solute carrier family 22, member 18
SLC38A2 solute carrier family 38, member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMR3B submaxillary gland androgen regulated protein 3B
SNAI2 snail family zinc finger 2
SOD1 superoxide dismutase 1, soluble
SOSTDC1 sclerostin domain containing 1
SRPK1 SRSF protein kinase 1
SRSF1 serine/arginine-rich splicing factor 1
SRY sex determining region Y
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
SYCP3 synaptonemal complex protein 3
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBXA2R thromboxane A2 receptor
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TES testin LIM domain protein
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP4 TIMP metallopeptidase inhibitor 4
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP73 tumor protein p73
TRIM28 tripartite motif containing 28
TRIM37 tripartite motif containing 37
TRIP13 thyroid hormone receptor interactor 13
TSC2 tuberous sclerosis 2
TSG101 tumor susceptibility 101
USP18 ubiquitin specific peptidase 18
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WFDC1 WAP four-disulfide core domain 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
WTIP Wilms tumor 1 interacting protein
WWOX WW domain containing oxidoreductase
ZFPM2 zinc finger protein, FOG family member 2