Childhood Leiomyosarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0279986
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Genes

126 genes associated with the disease Childhood Leiomyosarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ACVRL1 activin A receptor type II-like 1
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ARL4C ADP-ribosylation factor-like 4C
ATM ATM serine/threonine kinase
AXL AXL receptor tyrosine kinase
AZIN2 antizyme inhibitor 2
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BRCA1 breast cancer 1, early onset
CALD1 caldesmon 1
CCDC6 coiled-coil domain containing 6
CD163 CD163 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK8 cyclin-dependent kinase 8
CDKN2A cyclin-dependent kinase inhibitor 2A
CDO1 cysteine dioxygenase type 1
CETN1 centrin, EF-hand protein, 1
COIL coilin
COL1A1 collagen, type I, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
DAP death-associated protein
DDIT3 DNA-damage-inducible transcript 3
DES desmin
DHCR24 24-dehydrocholesterol reductase
DPEP1 dipeptidase 1 (renal)
E2F1 E2F transcription factor 1
ELN elastin
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FH fumarate hydratase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUS FUS RNA binding protein
GADD45B growth arrest and DNA-damage-inducible, beta
GADL1 glutamate decarboxylase-like 1
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
HDAC9 histone deacetylase 9
HHAT hedgehog acyltransferase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
IGF2 insulin-like growth factor 2
IL1R1 interleukin 1 receptor, type I
INSRR insulin receptor-related receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LEF1 lymphoid enhancer-binding factor 1
LMOD1 leiomodin 1 (smooth muscle)
MBD1 methyl-CpG binding domain protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED12 mediator complex subunit 12
MET MET proto-oncogene, receptor tyrosine kinase
MRC1 mannose receptor, C type 1
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
MYLK2 myosin light chain kinase 2
MYLK3 myosin light chain kinase 3
MYOCD myocardin
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NDC80 NDC80 kinetochore complex component
NKX2-5 NK2 homeobox 5
NPAS2 neuronal PAS domain protein 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCP4 Purkinje cell protein 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAG1 pleiomorphic adenoma gene 1
PNPLA2 patatin-like phospholipase domain containing 2
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PTEN phosphatase and tensin homolog
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RTL1 retrotransposon-like 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETMAR SET domain and mariner transposase fusion gene
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAI2 snail family zinc finger 2
SOCS3 suppressor of cytokine signaling 3
SP3 Sp3 transcription factor
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERT telomerase reverse transcriptase
TNS1 tensin 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TYRO3 TYRO3 protein tyrosine kinase
UBASH3A ubiquitin associated and SH3 domain containing A
USP18 ubiquitin specific peptidase 18
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
WDR20 WD repeat domain 20
WDR48 WD repeat domain 48
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZNF250 zinc finger protein 250
ZNF281 zinc finger protein 281