Childhood Soft Tissue Sarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0220645
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Genes

158 genes associated with the disease Childhood Soft Tissue Sarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ADAM17 ADAM metallopeptidase domain 17
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ANKRD36B ankyrin repeat domain 36B
ANPEP alanyl (membrane) aminopeptidase
ANTXR2 anthrax toxin receptor 2
ANXA5 annexin A5
AQP1 aquaporin 1 (Colton blood group)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF1 activating transcription factor 1
ATR ATR serine/threonine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2 B-cell CLL/lymphoma 2
BCOR BCL6 corepressor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CA9 carbonic anhydrase IX
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAVIN2 caveolae associated protein 2
CCL2 chemokine (C-C motif) ligand 2
CCNB3 cyclin B3
CD109 CD109 molecule
CD274 CD274 molecule
CD44 CD44 molecule (Indian blood group)
CD6 CD6 molecule
CD63 CD63 molecule
CD68 CD68 molecule
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CIC capicua transcriptional repressor
CLEC11A C-type lectin domain family 11, member A
CLOCK clock circadian regulator
COL11A2 collagen, type XI, alpha 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSPG4 chondroitin sulfate proteoglycan 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DHCR24 24-dehydrocholesterol reductase
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EPAS1 endothelial PAS domain protein 1
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ESRRB estrogen-related receptor beta
EWSR1 EWS RNA-binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188B family with sequence similarity 188, member B
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FUS FUS RNA binding protein
GSK3B glycogen synthase kinase 3 beta
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IRF8 interferon regulatory factor 8
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLLN killin, p53-regulated DNA replication inhibitor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LAG3 lymphocyte-activation gene 3
LMNA lamin A/C
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MITF microphthalmia-associated transcription factor
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MST1 macrophage stimulating 1
MTAP methylthioadenosine phosphorylase
MUC4 mucin 4, cell surface associated
MXI1 MAX interactor 1, dimerization protein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PARP1 poly (ADP-ribose) polymerase 1
PAX3 paired box 3
PCLAF PCNA clamp associated factor
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLIN1 perilipin 1
POU5F1 POU class 5 homeobox 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRIMA1 proline rich membrane anchor 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTPA protein phosphatase 2 phosphatase activator
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
S100A1 S100 calcium binding protein A1
S100A4 S100 calcium binding protein A4
S100B S100 calcium binding protein B
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPP1 secreted phosphoprotein 1
SS18 synovial sarcoma translocation, chromosome 18
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SSX2B synovial sarcoma, X breakpoint 2B
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK3 serine/threonine kinase 3
STS steroid sulfatase (microsomal), isozyme S
SYT1 synaptotagmin I
TACC3 transforming, acidic coiled-coil containing protein 3
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFE3 transcription factor binding to IGHM enhancer 3
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TSG101 tumor susceptibility 101
UQCRH ubiquinol-cytochrome c reductase hinge protein
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VGLL3 vestigial-like family member 3
VIM vimentin
VIP vasoactive intestinal peptide
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF654 zinc finger protein 654