| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.145305 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.11733 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.111241 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.106278 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.103452 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.103394 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0960709 |
| MKI67 | marker of proliferation Ki-67 | 0.0834571 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.073484 |
| RPS12 | ribosomal protein S12 | 0.0734497 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0733065 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0698411 |
| PCDH7 | protocadherin 7 | 0.0675441 |
| YBX3 | Y box binding protein 3 | 0.0620493 |
| CALR | calreticulin | 0.0619065 |
| ANXA1 | annexin A1 | 0.0612262 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0577331 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0534478 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0523965 |
| LDHA | lactate dehydrogenase A | 0.0505429 |
| KIF5B | kinesin family member 5B | 0.0490339 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0485398 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0479338 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0423925 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0408017 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0402019 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0397417 |
| ATP11A | ATPase, class VI, type 11A | 0.0391753 |
| TPR | translocated promoter region, nuclear basket protein | 0.0390982 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0390268 |
| TPM3 | tropomyosin 3 | 0.0369327 |
| ENO1 | enolase 1, (alpha) | 0.0367991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0362781 |
| XPO1 | exportin 1 | 0.0360523 |
| PDGFC | platelet derived growth factor C | 0.0350479 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0348876 |
| MATR3 | matrin 3 | 0.0348027 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0345655 |
| SET | SET nuclear proto-oncogene | 0.0344249 |
| ECT2 | epithelial cell transforming 2 | 0.0339488 |
| AFDN | afadin, adherens junction formation factor | 0.0336033 |
| ERBIN | erbb2 interacting protein | 0.0335443 |
| NLGN1 | neuroligin 1 | 0.0333832 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0318926 |
| CENPF | centromere protein F, 350/400kDa | 0.031676 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0316055 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0310878 |
| TMEM41B | transmembrane protein 41B | 0.030945 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0308974 |
| CMIP | c-Maf inducing protein | 0.0306736 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0305779 |
| LMO7 | LIM domain 7 | 0.0299762 |
| RPS3 | ribosomal protein S3 | 0.0293158 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0292601 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0290189 |
| CEP192 | centrosomal protein 192kDa | 0.0287915 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0284371 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0281561 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0279203 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0276281 |
| MORF4L2 | mortality factor 4 like 2 | 0.0275791 |
| HMGB2 | high mobility group box 2 | 0.0271065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0268315 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0267312 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0264469 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0263744 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0262273 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0259691 |
| TMSB10 | thymosin beta 10 | 0.0258115 |
| NEK7 | NIMA-related kinase 7 | 0.0250092 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0249459 |
| NDC80 | NDC80 kinetochore complex component | 0.0248047 |
| RPL23 | ribosomal protein L23 | 0.0246026 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0244032 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0242493 |
| PEG10 | paternally expressed 10 | 0.0239524 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0238137 |
| ANLN | anillin, actin binding protein | 0.0235104 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0234178 |
| KLF6 | Kruppel-like factor 6 | 0.0231833 |
| EFNA5 | ephrin-A5 | 0.0230919 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0228118 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0227891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0226266 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0222755 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0221793 |
| CCDC47 | coiled-coil domain containing 47 | 0.0221125 |
| RRM2 | ribonucleotide reductase M2 | 0.0220509 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0220451 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0220423 |
| PGK1 | phosphoglycerate kinase 1 | 0.0218902 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0218033 |
| EZR | ezrin | 0.0217758 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217605 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0216803 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0216277 |
| RPS7 | ribosomal protein S7 | 0.0216234 |
| CAVIN1 | caveolae associated protein 1 | 0.0215959 |
| ABI2 | abl-interactor 2 | 0.0212459 |
| AXIN2 | axin 2 | 0.0212403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.486681 |
| AREG | amphiregulin | -0.130491 |
| ACTG1 | actin gamma 1 | -0.105367 |
| VIM | vimentin | -0.0956747 |
| MMP12 | matrix metallopeptidase 12 | -0.0870209 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0862532 |
| POTEF | POTE ankyrin domain family, member F | -0.0793812 |
| TUBA1B | tubulin, alpha 1b | -0.0615597 |
| RPS6 | ribosomal protein S6 | -0.0603218 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0567263 |
| HMGA2 | high mobility group AT-hook 2 | -0.0532648 |
| EGR1 | early growth response 1 | -0.0532212 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0521968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0504012 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0501689 |
| RPS23 | ribosomal protein S23 | -0.0489848 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0477372 |
| BCHE | butyrylcholinesterase | -0.046885 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0445609 |
| HMGA1 | high mobility group AT-hook 1 | -0.0436108 |
| PTMA | prothymosin, alpha | -0.0416729 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.041368 |
| RPLP2 | ribosomal protein, large, P2 | -0.039301 |
| RPS15 | ribosomal protein S15 | -0.0380221 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0374958 |
| UBC | ubiquitin C | -0.0368027 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0352654 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0337654 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0331256 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0326583 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.032176 |
| JMJD1C | jumonji domain containing 1C | -0.0314537 |
| VMP1 | vacuole membrane protein 1 | -0.0305166 |
| SETD5 | SET domain containing 5 | -0.0303839 |
| RPS29 | ribosomal protein S29 | -0.0303134 |
| ZNF804A | zinc finger protein 804A | -0.0296502 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0293153 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0291901 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0287991 |
| EHBP1 | EH domain binding protein 1 | -0.0286371 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0286304 |
| SESN2 | sestrin 2 | -0.0285791 |
| RPL19 | ribosomal protein L19 | -0.0281225 |
| LDHB | lactate dehydrogenase B | -0.0275379 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027409 |
| RPS5 | ribosomal protein S5 | -0.0259872 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0256727 |
| RPS16 | ribosomal protein S16 | -0.0253705 |
| RPS21 | ribosomal protein S21 | -0.0249198 |
| S100A10 | S100 calcium binding protein A10 | -0.0248884 |
| RPS10 | ribosomal protein S10 | -0.0245057 |
| RPS24 | ribosomal protein S24 | -0.0237827 |
| MAP1B | microtubule-associated protein 1B | -0.0237192 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0236331 |
| RAB10 | RAB10, member RAS oncogene family | -0.0233836 |
| NABP1 | nucleic acid binding protein 1 | -0.0233419 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0229928 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0225243 |
| H3-3B | H3.3 histone B | -0.0224961 |
| GCG | glucagon | -0.0224579 |
| RPS13 | ribosomal protein S13 | -0.0220961 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0218943 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0218554 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0217967 |
| RPL8 | ribosomal protein L8 | -0.021784 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0212341 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0211436 |
| WASF2 | WAS protein family, member 2 | -0.0209743 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.020599 |
| RPLP0 | ribosomal protein, large, P0 | -0.0205496 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0202778 |
| HLA-A | major histocompatibility complex, class I, A | -0.0199948 |
| CBX3 | chromobox homolog 3 | -0.0197056 |
| PFN1 | profilin 1 | -0.0193628 |
| RPS11 | ribosomal protein S11 | -0.0193475 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0192998 |
| RPL28 | ribosomal protein L28 | -0.0192563 |
| TUBB | tubulin, beta class I | -0.0191008 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0190189 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0189436 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0188206 |
| HDGF | hepatoma-derived growth factor | -0.0186595 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0186363 |
| RSF1 | remodeling and spacing factor 1 | -0.0185034 |
| ACLY | ATP citrate lyase | -0.0183114 |
| CPOX | coproporphyrinogen oxidase | -0.0182879 |
| RPL21 | ribosomal protein L21 | -0.0182105 |
| CCND1 | cyclin D1 | -0.0181814 |
| CUX1 | cut-like homeobox 1 | -0.0181552 |
| SCFD1 | sec1 family domain containing 1 | -0.017814 |
| BRD4 | bromodomain containing 4 | -0.0177301 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0177067 |
| BRD2 | bromodomain containing 2 | -0.0175011 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0171145 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0171025 |
| FNIP1 | folliculin interacting protein 1 | -0.0169037 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0168109 |
| RPS25 | ribosomal protein S25 | -0.0165739 |
| KLHL24 | kelch-like family member 24 | -0.0165606 |
| NAV3 | neuron navigator 3 | -0.0164503 |