| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.15613 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.142089 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.139521 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.102574 |
| NDRG1 | N-myc downstream regulated 1 | 0.0750369 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0744796 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0664183 |
| TPM3 | tropomyosin 3 | 0.06342 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0614879 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0588625 |
| CD44 | CD44 molecule (Indian blood group) | 0.0588556 |
| B2M | beta-2-microglobulin | 0.0547898 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0517721 |
| PAX8 | paired box 8 | 0.0498941 |
| CALR | calreticulin | 0.049768 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.049717 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0485253 |
| MSN | moesin | 0.0464462 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0464136 |
| FAT1 | FAT atypical cadherin 1 | 0.0454147 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0452519 |
| ATP13A3 | ATPase type 13A3 | 0.0441957 |
| PTK2 | protein tyrosine kinase 2 | 0.0437753 |
| ARRDC3 | arrestin domain containing 3 | 0.0433425 |
| CMIP | c-Maf inducing protein | 0.0432235 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.042463 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0420778 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0418562 |
| SMAD3 | SMAD family member 3 | 0.0418102 |
| GPC6 | glypican 6 | 0.0417283 |
| SET | SET nuclear proto-oncogene | 0.0416119 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0410766 |
| RUNX1 | runt-related transcription factor 1 | 0.0408643 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0394483 |
| SEPTIN9 | septin 9 | 0.039055 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0385688 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0371981 |
| RND3 | Rho family GTPase 3 | 0.036593 |
| SP3 | Sp3 transcription factor | 0.0360522 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0357706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0357371 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.034436 |
| NAV2 | neuron navigator 2 | 0.0342131 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0338139 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0329094 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0328284 |
| ETV6 | ets variant 6 | 0.032443 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0321502 |
| CADM1 | cell adhesion molecule 1 | 0.0320507 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0320278 |
| RPL3 | ribosomal protein L3 | 0.0317268 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0314153 |
| BNC2 | basonuclin 2 | 0.030954 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0305249 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0302953 |
| LOXL2 | lysyl oxidase-like 2 | 0.0301608 |
| NRP2 | neuropilin 2 | 0.0301285 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0300445 |
| RPS12 | ribosomal protein S12 | 0.0297122 |
| PFN1 | profilin 1 | 0.0295993 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0292436 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0288628 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0287273 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0286747 |
| SLTM | SAFB-like, transcription modulator | 0.0285472 |
| LDHA | lactate dehydrogenase A | 0.0284913 |
| IRS2 | insulin receptor substrate 2 | 0.02836 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.028271 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0282086 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0278651 |
| RIC1 | RAB6A GEF complex partner 1 | 0.027805 |
| RTN4 | reticulon 4 | 0.0276724 |
| TGFB2 | transforming growth factor, beta 2 | 0.0276076 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0273562 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0272438 |
| VEGFA | vascular endothelial growth factor A | 0.0268128 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0265952 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0265662 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0265374 |
| FMNL2 | formin-like 2 | 0.0263515 |
| USP12 | ubiquitin specific peptidase 12 | 0.0262342 |
| MYO10 | myosin X | 0.0260487 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0259848 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0259084 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257956 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0257213 |
| DENND2B | DENN domain containing 2B | 0.0256781 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0256187 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.025331 |
| RPS7 | ribosomal protein S7 | 0.0253157 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0251492 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0251412 |
| RPL23 | ribosomal protein L23 | 0.0248283 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0248237 |
| RASA2 | RAS p21 protein activator 2 | 0.024727 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0243553 |
| TNS1 | tensin 1 | 0.0240277 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0239294 |
| EFHD2 | EF-hand domain family, member D2 | 0.0235144 |
| RPS2 | ribosomal protein S2 | 0.023502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.184133 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11213 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989155 |
| VIM | vimentin | -0.0938846 |
| RRBP1 | ribosome binding protein 1 | -0.0860694 |
| FTL | ferritin, light polypeptide | -0.0771454 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0601547 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0586141 |
| RPS24 | ribosomal protein S24 | -0.0558474 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.052525 |
| CAVIN1 | caveolae associated protein 1 | -0.0508629 |
| HDLBP | high density lipoprotein binding protein | -0.0501771 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0497059 |
| PTMA | prothymosin, alpha | -0.0489874 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479067 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0476645 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0452529 |
| ARF1 | ADP-ribosylation factor 1 | -0.0442667 |
| TKT | transketolase | -0.0432487 |
| CP | ceruloplasmin (ferroxidase) | -0.0428178 |
| SDCBP | syndecan binding protein (syntenin) | -0.0421294 |
| RPS6 | ribosomal protein S6 | -0.0419429 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0417365 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0401597 |
| TMEM263 | transmembrane protein 263 | -0.039301 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0381739 |
| VCL | vinculin | -0.0377626 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0375078 |
| CANX | calnexin | -0.0365946 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0363141 |
| PKM | pyruvate kinase, muscle | -0.0358474 |
| RIGI | RNA sensor RIG-I | -0.0358413 |
| SP100 | SP100 nuclear antigen | -0.0357376 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0356611 |
| UBC | ubiquitin C | -0.035515 |
| AHNAK | AHNAK nucleoprotein | -0.0338765 |
| MAP1B | microtubule-associated protein 1B | -0.0336575 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0333446 |
| MTDH | metadherin | -0.0329256 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0324175 |
| ACTG1 | actin gamma 1 | -0.0321084 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0315913 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0312553 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.030959 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0306176 |
| SQSTM1 | sequestosome 1 | -0.0302681 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0301935 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0301305 |
| TUBB | tubulin, beta class I | -0.0300443 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0298554 |
| FUS | FUS RNA binding protein | -0.0297413 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0297405 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0296258 |
| SRP72 | signal recognition particle 72kDa | -0.0295849 |
| HMGB1 | high mobility group box 1 | -0.0295817 |
| RPS5 | ribosomal protein S5 | -0.0289415 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0283989 |
| CA12 | carbonic anhydrase XII | -0.0283517 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0280269 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.02792 |
| CALD1 | caldesmon 1 | -0.0275375 |
| RPLP1 | ribosomal protein, large, P1 | -0.0274976 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0273463 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273457 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0272706 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0271615 |
| ANXA2 | annexin A2 | -0.0269923 |
| GNAS | GNAS complex locus | -0.0269813 |
| GDF15 | growth differentiation factor 15 | -0.0267335 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0265062 |
| PALLD | palladin, cytoskeletal associated protein | -0.0264415 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.026391 |
| CEP350 | centrosomal protein 350kDa | -0.0262582 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258266 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0257844 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0256556 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.025002 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0242765 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0241538 |
| CENPF | centromere protein F, 350/400kDa | -0.0241503 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0241378 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0241334 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0240528 |
| RPLP0 | ribosomal protein, large, P0 | -0.0237624 |
| GOLGB1 | golgin B1 | -0.0234333 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232167 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0227873 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0227258 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0226398 |
| RPS4X | ribosomal protein S4, X-linked | -0.022612 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0225521 |
| SEC24D | SEC24 family member D | -0.0224502 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0223663 |
| RPL28 | ribosomal protein L28 | -0.0222439 |
| XAF1 | XIAP associated factor 1 | -0.0220257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0219414 |
| GOLGA3 | golgin A3 | -0.0217976 |
| THOC2 | THO complex 2 | -0.0217054 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0216329 |
| H3-3B | H3.3 histone B | -0.0214013 |