| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.144514 |
| NDRG1 | N-myc downstream regulated 1 | 0.121757 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10142 |
| TMSB10 | thymosin beta 10 | 0.100556 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0980069 |
| DST | dystonin | 0.097795 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0835766 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0829318 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0797306 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0772256 |
| RPS12 | ribosomal protein S12 | 0.0726914 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0721147 |
| IGF2 | insulin-like growth factor 2 | 0.0682842 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0679866 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0672961 |
| RPL35A | ribosomal protein L35a | 0.0668285 |
| COL5A1 | collagen, type V, alpha 1 | 0.0664034 |
| RPL23 | ribosomal protein L23 | 0.0652605 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0631571 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0616075 |
| LAMB3 | laminin, beta 3 | 0.0577931 |
| ENO1 | enolase 1, (alpha) | 0.0562497 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0549291 |
| SET | SET nuclear proto-oncogene | 0.0548231 |
| SEPTIN9 | septin 9 | 0.0542685 |
| RPS8 | ribosomal protein S8 | 0.0532281 |
| CALR | calreticulin | 0.0532121 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0529909 |
| RPS3 | ribosomal protein S3 | 0.0480574 |
| RPL12 | ribosomal protein L12 | 0.047817 |
| RPL37A | ribosomal protein L37a | 0.0458151 |
| RPS19 | ribosomal protein S19 | 0.0453612 |
| FAM13A | family with sequence similarity 13, member A | 0.0429615 |
| RRM2 | ribonucleotide reductase M2 | 0.0426644 |
| RPL11 | ribosomal protein L11 | 0.0425976 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0424638 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.040038 |
| RPL9 | ribosomal protein L9 | 0.0399905 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0398947 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0398527 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0397408 |
| PTK2 | protein tyrosine kinase 2 | 0.0378984 |
| SMAD3 | SMAD family member 3 | 0.0367911 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0364173 |
| RPLP1 | ribosomal protein, large, P1 | 0.0360511 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0360086 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0359663 |
| CAPRIN2 | caprin family member 2 | 0.035799 |
| FTL | ferritin, light polypeptide | 0.0352909 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0342035 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0341583 |
| LDHA | lactate dehydrogenase A | 0.034066 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0334981 |
| VEGFA | vascular endothelial growth factor A | 0.0333441 |
| HPCAL1 | hippocalcin-like 1 | 0.0329956 |
| YBX1 | Y box binding protein 1 | 0.0328763 |
| B2M | beta-2-microglobulin | 0.031965 |
| RPL26 | ribosomal protein L26 | 0.0318461 |
| TPM3 | tropomyosin 3 | 0.031834 |
| RPS17 | ribosomal protein S17 | 0.0316658 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0314168 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0312659 |
| MCL1 | myeloid cell leukemia 1 | 0.0312535 |
| MLPH | melanophilin | 0.0311095 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0311085 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0307526 |
| RPL3 | ribosomal protein L3 | 0.0305423 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0304608 |
| RPL7 | ribosomal protein L7 | 0.0300955 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0300734 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0297683 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296009 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0295081 |
| NUP58 | nucleoporin 58 | 0.0292799 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0292339 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0290188 |
| RPS13 | ribosomal protein S13 | 0.0287668 |
| ADM | adrenomedullin | 0.0286409 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.028395 |
| TNS1 | tensin 1 | 0.0281291 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0280182 |
| RPL19 | ribosomal protein L19 | 0.0279481 |
| EFNA5 | ephrin-A5 | 0.0279042 |
| RNF24 | ring finger protein 24 | 0.0278485 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.027756 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0276549 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0275428 |
| RPS27A | ribosomal protein S27a | 0.027487 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0274024 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0273274 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0272631 |
| PCBP2 | poly(rC) binding protein 2 | 0.0270324 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0265924 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0264754 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0262431 |
| RPS4X | ribosomal protein S4, X-linked | 0.0261181 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0259263 |
| FLNB | filamin B, beta | 0.0258623 |
| RUNX1 | runt-related transcription factor 1 | 0.0258467 |
| PDE10A | phosphodiesterase 10A | 0.0255692 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260882 |
| FN1 | fibronectin 1 | -0.226587 |
| VIM | vimentin | -0.132707 |
| AHNAK | AHNAK nucleoprotein | -0.124497 |
| CDH13 | cadherin 13 | -0.116008 |
| CDCP1 | CUB domain containing protein 1 | -0.0875964 |
| RRBP1 | ribosome binding protein 1 | -0.0839881 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0765066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0618385 |
| CCND1 | cyclin D1 | -0.0609518 |
| EGR1 | early growth response 1 | -0.0595928 |
| ACTG1 | actin gamma 1 | -0.0560065 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0536253 |
| MT1E | metallothionein 1E | -0.0519893 |
| HDLBP | high density lipoprotein binding protein | -0.049161 |
| COL1A1 | collagen, type I, alpha 1 | -0.0479891 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0463778 |
| CANX | calnexin | -0.0451067 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0431411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0427378 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0406336 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0402581 |
| CALU | calumenin | -0.038843 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0363607 |
| TMEM263 | transmembrane protein 263 | -0.0345133 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0339398 |
| TNNC1 | troponin C type 1 (slow) | -0.0331365 |
| SEC24D | SEC24 family member D | -0.0327521 |
| TUBB | tubulin, beta class I | -0.0326437 |
| GNAS | GNAS complex locus | -0.0324291 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0321556 |
| MT2A | metallothionein 2A | -0.0321239 |
| RTN4 | reticulon 4 | -0.0319397 |
| CLIC4 | chloride intracellular channel 4 | -0.0318469 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0314789 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0314336 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0310652 |
| NF1 | neurofibromin 1 | -0.0301485 |
| TPM4 | tropomyosin 4 | -0.0300834 |
| OSMR | oncostatin M receptor | -0.0293929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0293053 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0291968 |
| TUBB6 | tubulin, beta 6 class V | -0.0289366 |
| CAVIN1 | caveolae associated protein 1 | -0.0274411 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0271197 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0266302 |
| PKM | pyruvate kinase, muscle | -0.0265377 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0264642 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0262581 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0258028 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0257011 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0255998 |
| ARF1 | ADP-ribosylation factor 1 | -0.025571 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0253024 |
| CEP95 | centrosomal protein 95kDa | -0.0249622 |
| WASF2 | WAS protein family, member 2 | -0.0248753 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0246905 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0246664 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.024448 |
| ANXA2 | annexin A2 | -0.0244383 |
| SGO2 | shugoshin 2 | -0.0243184 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0239937 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0235153 |
| HM13 | histocompatibility (minor) 13 | -0.0232921 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0230732 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0227019 |
| LOXL2 | lysyl oxidase-like 2 | -0.0224696 |
| FRMD4A | FERM domain containing 4A | -0.0224067 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0218355 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0216896 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0215366 |
| ARF4 | ADP-ribosylation factor 4 | -0.02152 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0213034 |
| COPA | coatomer protein complex, subunit alpha | -0.021186 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0206214 |
| TNS3 | tensin 3 | -0.0206103 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0204452 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0204261 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0203469 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0202446 |
| PRELID2 | PRELI domain containing 2 | -0.0201902 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0201704 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0200923 |
| PXDN | peroxidasin | -0.0200028 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.020002 |
| IL1B | interleukin 1, beta | -0.019869 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0198521 |
| MMP12 | matrix metallopeptidase 12 | -0.0196756 |
| MAP1B | microtubule-associated protein 1B | -0.019586 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0192396 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0191424 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0191093 |
| NKTR | natural killer cell triggering receptor | -0.0186084 |
| TXLNG | taxilin gamma | -0.018573 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0182815 |
| MAP4 | microtubule-associated protein 4 | -0.0181106 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0177304 |
| SBF2 | SET binding factor 2 | -0.0177244 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0174317 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0174119 |
