| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Chlorhexidine (diacetate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.306043 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.260424 |
| FN1 | fibronectin 1 | 0.169221 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137423 |
| CD44 | CD44 molecule (Indian blood group) | 0.105206 |
| MT2A | metallothionein 2A | 0.0933726 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0896861 |
| STC1 | stanniocalcin 1 | 0.0787425 |
| EXT1 | exostosin glycosyltransferase 1 | 0.074619 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.071847 |
| SMAD3 | SMAD family member 3 | 0.0705941 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0663229 |
| ATP13A3 | ATPase type 13A3 | 0.0636418 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0633691 |
| HMGA2 | high mobility group AT-hook 2 | 0.0629265 |
| ARRDC3 | arrestin domain containing 3 | 0.0565314 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0558309 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0542451 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0480062 |
| CALR | calreticulin | 0.0479039 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0475844 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0452665 |
| RASA2 | RAS p21 protein activator 2 | 0.0449011 |
| PTK2 | protein tyrosine kinase 2 | 0.0428872 |
| LOXL2 | lysyl oxidase-like 2 | 0.0427891 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0426377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0413949 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0403959 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0394342 |
| HAS2 | hyaluronan synthase 2 | 0.0377638 |
| ENO1 | enolase 1, (alpha) | 0.0372853 |
| ANTXR2 | anthrax toxin receptor 2 | 0.037264 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0365117 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0351923 |
| KLF6 | Kruppel-like factor 6 | 0.0350667 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0348314 |
| FAT1 | FAT atypical cadherin 1 | 0.0340184 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0339851 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.033628 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333124 |
| VEGFA | vascular endothelial growth factor A | 0.0329696 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0329306 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0328493 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0317124 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0313268 |
| LDHA | lactate dehydrogenase A | 0.0311852 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0295728 |
| FNDC3B | fibronectin type III domain containing 3B | 0.029023 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0289401 |
| TPM3 | tropomyosin 3 | 0.0285994 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0283375 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0280055 |
| VEGFC | vascular endothelial growth factor C | 0.0278723 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0274027 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0270631 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0266764 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0265305 |
| INHBA | inhibin, beta A | 0.0264512 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0257841 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0256672 |
| DST | dystonin | 0.0254883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0251747 |
| ASPH | aspartate beta-hydroxylase | 0.0250704 |
| SVIL | supervillin | 0.0250252 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0246812 |
| PLEC | plectin | 0.0244954 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.024465 |
| MYO10 | myosin X | 0.0241167 |
| MSN | moesin | 0.0240674 |
| FLNB | filamin B, beta | 0.0238692 |
| MLF1 | myeloid leukemia factor 1 | 0.0236818 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0236216 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0234064 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0229008 |
| RPL3 | ribosomal protein L3 | 0.0223777 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0222997 |
| FMNL2 | formin-like 2 | 0.0222871 |
| TXNRD1 | thioredoxin reductase 1 | 0.0222429 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0220134 |
| YEATS2 | YEATS domain containing 2 | 0.0214274 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0212359 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0210541 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0210141 |
| RPS12 | ribosomal protein S12 | 0.0207143 |
| AFAP1 | actin filament associated protein 1 | 0.0201662 |
| DUSP6 | dual specificity phosphatase 6 | 0.0201189 |
| FAM107B | family with sequence similarity 107, member B | 0.0200618 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.019869 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0198529 |
| EFNA5 | ephrin-A5 | 0.0198506 |
| GANAB | glucosidase, alpha; neutral AB | 0.0197236 |
| KIF1B | kinesin family member 1B | 0.0195422 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0193657 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0193401 |
| ZNF292 | zinc finger protein 292 | 0.0192338 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0191872 |
| SEPTIN9 | septin 9 | 0.0191273 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0191203 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.01902 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0190198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.307192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131986 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123233 |
| CDH13 | cadherin 13 | -0.0996083 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.082402 |
| COL1A1 | collagen, type I, alpha 1 | -0.0804874 |
| IER3 | immediate early response 3 | -0.0792037 |
| CADM1 | cell adhesion molecule 1 | -0.074203 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0691099 |
| VIM | vimentin | -0.0681015 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0658798 |
| COL1A2 | collagen, type I, alpha 2 | -0.0532648 |
| SQSTM1 | sequestosome 1 | -0.0521004 |
| MTDH | metadherin | -0.049504 |
| FTL | ferritin, light polypeptide | -0.0485527 |
| UBC | ubiquitin C | -0.0473467 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0465375 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0448657 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0434891 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0431515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0415434 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0414154 |
| NDRG1 | N-myc downstream regulated 1 | -0.0401145 |
| FBN1 | fibrillin 1 | -0.039388 |
| AHNAK | AHNAK nucleoprotein | -0.0386145 |
| RPS6 | ribosomal protein S6 | -0.0379554 |
| CANX | calnexin | -0.0378618 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0376567 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0358156 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0354248 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0353122 |
| GOLGB1 | golgin B1 | -0.0334185 |
| ACTG1 | actin gamma 1 | -0.0315515 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0315095 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0314912 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0309666 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0309114 |
| HDLBP | high density lipoprotein binding protein | -0.0305983 |
| GNAS | GNAS complex locus | -0.0300426 |
| TRAM1 | translocation associated membrane protein 1 | -0.0299516 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0297839 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296937 |
| RPL28 | ribosomal protein L28 | -0.029143 |
| PKM | pyruvate kinase, muscle | -0.0288079 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0282215 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.028058 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0278737 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.027669 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0273186 |
| PTMA | prothymosin, alpha | -0.0265004 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0262764 |
| CAVIN1 | caveolae associated protein 1 | -0.0259702 |
| RTN3 | reticulon 3 | -0.0256304 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0254499 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0252692 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0250088 |
| INTS6 | integrator complex subunit 6 | -0.0245807 |
| RAB1A | RAB1A, member RAS oncogene family | -0.024182 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0238318 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.023776 |
| HDAC9 | histone deacetylase 9 | -0.0235288 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0234049 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0233447 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0231825 |
| QKI | QKI, KH domain containing, RNA binding | -0.0226047 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0225393 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0224157 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0223696 |
| FNIP1 | folliculin interacting protein 1 | -0.0222629 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0221363 |
| RRBP1 | ribosome binding protein 1 | -0.0219571 |
| LOX | lysyl oxidase | -0.0219551 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0218974 |
| SP100 | SP100 nuclear antigen | -0.0213013 |
| RPS24 | ribosomal protein S24 | -0.0203438 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0202709 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0202693 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0202292 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0201205 |
| RPL8 | ribosomal protein L8 | -0.0200189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.019988 |
| WASF2 | WAS protein family, member 2 | -0.0198527 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.019483 |
| RPLP0 | ribosomal protein, large, P0 | -0.0194221 |
| CUX1 | cut-like homeobox 1 | -0.0192245 |
| RHEB | Ras homolog enriched in brain | -0.0191839 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0191321 |
| SESN2 | sestrin 2 | -0.018858 |
| LRRC49 | leucine rich repeat containing 49 | -0.0187395 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0186257 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0185887 |
| ATM | ATM serine/threonine kinase | -0.0185478 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0185179 |
| CA12 | carbonic anhydrase XII | -0.0185151 |
| SEC24D | SEC24 family member D | -0.0184669 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0184344 |
| RPS20 | ribosomal protein S20 | -0.0184304 |
| ATF4 | activating transcription factor 4 | -0.0181567 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0180406 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0177286 |
