| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.172583 |
| ATXN1 | ataxin 1 | 0.112873 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.104255 |
| LMO7 | LIM domain 7 | 0.10017 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0916182 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0823723 |
| PTK2 | protein tyrosine kinase 2 | 0.0808261 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.071662 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0678224 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0657432 |
| FOXO1 | forkhead box O1 | 0.0626874 |
| NF1 | neurofibromin 1 | 0.0623996 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0620195 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0559365 |
| AFDN | afadin, adherens junction formation factor | 0.0550026 |
| ACTN4 | actinin, alpha 4 | 0.0544832 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0541993 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.054155 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0540479 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0523935 |
| STK24 | serine/threonine kinase 24 | 0.0522029 |
| BCL2L1 | BCL2-like 1 | 0.0520964 |
| KRT18 | keratin 18, type I | 0.0513689 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.050769 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0482123 |
| PKP4 | plakophilin 4 | 0.0476486 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0469664 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0468304 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0463931 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0462857 |
| OGA | O-GlcNAcase | 0.0461603 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0459368 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0458371 |
| DST | dystonin | 0.0457437 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0448934 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0446128 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0440974 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0439634 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0434476 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0431264 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0429618 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0423346 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0410277 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0394379 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.038878 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0385791 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0384224 |
| PLAUR | plasminogen activator, urokinase receptor | 0.038378 |
| ETV6 | ets variant 6 | 0.0383432 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0382757 |
| LAMB3 | laminin, beta 3 | 0.0382528 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0380948 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0378263 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0377362 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.037728 |
| ANXA11 | annexin A11 | 0.0376557 |
| FAM135A | family with sequence similarity 135, member A | 0.0375103 |
| TPM3 | tropomyosin 3 | 0.0373108 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0371103 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0368115 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.03678 |
| EXPH5 | exophilin 5 | 0.0367759 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0367341 |
| EXOC4 | exocyst complex component 4 | 0.0359596 |
| JMJD1C | jumonji domain containing 1C | 0.035941 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0359325 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0359043 |
| ITGB4 | integrin, beta 4 | 0.0355764 |
| GOLGB1 | golgin B1 | 0.0352164 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0350595 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0349882 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0348719 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0348499 |
| TJP2 | tight junction protein 2 | 0.034789 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0347577 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0346027 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0344354 |
| WWC1 | WW and C2 domain containing 1 | 0.0343546 |
| MKI67 | marker of proliferation Ki-67 | 0.0342671 |
| SMAD3 | SMAD family member 3 | 0.0340146 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330667 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0329081 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0328403 |
| RPS12 | ribosomal protein S12 | 0.032752 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0327215 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0320302 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031872 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0314158 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.031375 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.0313458 |
| LMNA | lamin A/C | 0.0313003 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0311756 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0310264 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0308741 |
| SPATA13 | spermatogenesis associated 13 | 0.0306679 |
| CUL4A | cullin 4A | 0.0304484 |
| SEPTIN9 | septin 9 | 0.0304078 |
| ERBIN | erbb2 interacting protein | 0.0303868 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0302413 |
| FAT1 | FAT atypical cadherin 1 | 0.0302108 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.206179 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16047 |
| INTS6 | integrator complex subunit 6 | -0.10319 |
| RPS6 | ribosomal protein S6 | -0.0918446 |
| KRT20 | keratin 20, type I | -0.085855 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0843856 |
| PKM | pyruvate kinase, muscle | -0.0831216 |
| LYZ | lysozyme | -0.0786522 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.075985 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0745855 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.074414 |
| NDRG1 | N-myc downstream regulated 1 | -0.0659602 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0637167 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0600814 |
| FRY | furry homolog (Drosophila) | -0.0557082 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0549794 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0516645 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0506065 |
| EGR1 | early growth response 1 | -0.0503551 |
| RPLP0 | ribosomal protein, large, P0 | -0.0497777 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.049349 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0475534 |
| FOXO3 | forkhead box O3 | -0.0457388 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0452855 |
| POF1B | premature ovarian failure, 1B | -0.0450544 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0443983 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0443566 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0430061 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0417579 |
| GNAS | GNAS complex locus | -0.0417071 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0410833 |
| RPLP1 | ribosomal protein, large, P1 | -0.0403156 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0395451 |
| VCL | vinculin | -0.0392348 |
| INSIG1 | insulin induced gene 1 | -0.0391767 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0374602 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0356755 |
| RPL28 | ribosomal protein L28 | -0.0355477 |
| KRT19 | keratin 19, type I | -0.0353597 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.035109 |
| JUN | jun proto-oncogene | -0.033365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0333168 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331484 |
| ACTG1 | actin gamma 1 | -0.0327877 |
| RPL12 | ribosomal protein L12 | -0.0322855 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0322676 |
| AHNAK | AHNAK nucleoprotein | -0.032143 |
| MT2A | metallothionein 2A | -0.0320064 |
| FBXO32 | F-box protein 32 | -0.0318555 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0308231 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0304824 |
| FAM13A | family with sequence similarity 13, member A | -0.0303408 |
| SERTAD2 | SERTA domain containing 2 | -0.0300555 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.029524 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0283877 |
| LDHA | lactate dehydrogenase A | -0.0279879 |
| S100A10 | S100 calcium binding protein A10 | -0.0278524 |
| TPI1 | triosephosphate isomerase 1 | -0.0277573 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0273578 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0273436 |
| VIM | vimentin | -0.0269049 |
| PERP | PERP, TP53 apoptosis effector | -0.026823 |
| RPS23 | ribosomal protein S23 | -0.0267866 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0267708 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0261895 |
| SQSTM1 | sequestosome 1 | -0.0257207 |
| SNX14 | sorting nexin 14 | -0.0256363 |
| RPLP2 | ribosomal protein, large, P2 | -0.0254417 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0253465 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0250316 |
| TLE4 | transducin-like enhancer of split 4 | -0.0242281 |
| ARF4 | ADP-ribosylation factor 4 | -0.024087 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.023886 |
| RPL21 | ribosomal protein L21 | -0.0238482 |
| PTMA | prothymosin, alpha | -0.0236474 |
| POTEF | POTE ankyrin domain family, member F | -0.0236469 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0234928 |
| PRR5L | proline rich 5 like | -0.0233836 |
| RPL27A | ribosomal protein L27a | -0.0233647 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0232822 |
| PHF3 | PHD finger protein 3 | -0.0231818 |
| RPL19 | ribosomal protein L19 | -0.0226176 |
| RPS16 | ribosomal protein S16 | -0.022583 |
| RPS20 | ribosomal protein S20 | -0.0223871 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0223704 |
| ADM | adrenomedullin | -0.0222246 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.02217 |
| WDR45B | WD repeat domain 45B | -0.0221498 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0216703 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0211819 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0210442 |
| LAMA4 | laminin, alpha 4 | -0.0208038 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0207673 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0206144 |
| SESN2 | sestrin 2 | -0.0201993 |
| RPS24 | ribosomal protein S24 | -0.0201458 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0200085 |
| RPS5 | ribosomal protein S5 | -0.0199797 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0199556 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0198384 |