| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | 0.289052 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.111445 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.110995 |
| CFB | complement factor B | 0.1103 |
| FNDC3B | fibronectin type III domain containing 3B | 0.104018 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0980904 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0894008 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0865573 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.083509 |
| RPS12 | ribosomal protein S12 | 0.0772295 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0770595 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0723664 |
| AFDN | afadin, adherens junction formation factor | 0.0671526 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0655935 |
| SVIL | supervillin | 0.0648839 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0637287 |
| FAT1 | FAT atypical cadherin 1 | 0.0586505 |
| MRTFA | myocardin related transcription factor A | 0.057765 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0576675 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0575456 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0575338 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0574165 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0555574 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0534708 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0525813 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0502269 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0499411 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0490867 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0469284 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0463665 |
| ITGB5 | integrin, beta 5 | 0.0462577 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0457317 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0453582 |
| SMAD3 | SMAD family member 3 | 0.0442468 |
| RPL37A | ribosomal protein L37a | 0.0434663 |
| FN1 | fibronectin 1 | 0.0431964 |
| RTN4 | reticulon 4 | 0.0429826 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0421432 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0418705 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0410213 |
| TXNRD1 | thioredoxin reductase 1 | 0.0409681 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0388982 |
| YAP1 | Yes-associated protein 1 | 0.0386772 |
| ENO1 | enolase 1, (alpha) | 0.0376398 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0375483 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0373822 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0372197 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0370143 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0368229 |
| RELL1 | RELT-like 1 | 0.0356248 |
| RPL23 | ribosomal protein L23 | 0.0353362 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0349951 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0344328 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.034083 |
| HLF | hepatic leukemia factor | 0.0336513 |
| BCL2L1 | BCL2-like 1 | 0.0334484 |
| JMJD1C | jumonji domain containing 1C | 0.0334063 |
| OSMR | oncostatin M receptor | 0.0332589 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0331767 |
| JAK1 | Janus kinase 1 | 0.0330373 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0325545 |
| CRLS1 | cardiolipin synthase 1 | 0.032395 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0319726 |
| FOXO1 | forkhead box O1 | 0.0316497 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0315442 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0314003 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0313657 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.03117 |
| ALPK2 | alpha-kinase 2 | 0.0310246 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0308787 |
| PELO | pelota homolog (Drosophila) | 0.030786 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0305297 |
| KLF6 | Kruppel-like factor 6 | 0.0297336 |
| FRMD5 | FERM domain containing 5 | 0.0295131 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0291585 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0291422 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0291181 |
| PLAC8 | placenta-specific 8 | 0.0290986 |
| SET | SET nuclear proto-oncogene | 0.0288768 |
| RPS7 | ribosomal protein S7 | 0.0286981 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0284822 |
| NCKAP1 | NCK-associated protein 1 | 0.0283827 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0282913 |
| RPL26 | ribosomal protein L26 | 0.0280418 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0279231 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0278041 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274788 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0271667 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0265239 |
| ENAH | enabled homolog (Drosophila) | 0.0264615 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0261867 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0261811 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.026046 |
| PKP4 | plakophilin 4 | 0.0257955 |
| FERMT1 | fermitin family member 1 | 0.025657 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0255765 |
| CLTB | clathrin, light chain B | 0.0255382 |
| JAG1 | jagged 1 | 0.0255238 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0252981 |
| IL4R | interleukin 4 receptor | 0.0252877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.245771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116252 |
| AHSG | alpha-2-HS-glycoprotein | -0.101625 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0992432 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0932826 |
| CP | ceruloplasmin (ferroxidase) | -0.092047 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0911031 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0871051 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0851586 |
| APOA2 | apolipoprotein A-II | -0.0844821 |
| MT2A | metallothionein 2A | -0.0825206 |
| GK | glycerol kinase | -0.0755389 |
| FTL | ferritin, light polypeptide | -0.0750768 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0750559 |
| INTS6 | integrator complex subunit 6 | -0.0717342 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.071038 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0673899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0669068 |
| GNAS | GNAS complex locus | -0.0574997 |
| RPS6 | ribosomal protein S6 | -0.0568895 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0553637 |
| NPR2 | natriuretic peptide receptor 2 | -0.0542745 |
| PLIN2 | perilipin 2 | -0.0536627 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0522545 |
| FAM107B | family with sequence similarity 107, member B | -0.048378 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0472941 |
| RPS24 | ribosomal protein S24 | -0.0457125 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0433008 |
| STK17A | serine/threonine kinase 17a | -0.041012 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0407492 |
| NDRG1 | N-myc downstream regulated 1 | -0.0401615 |
| C3 | complement component 3 | -0.0400723 |
| MT1E | metallothionein 1E | -0.0394854 |
| HDLBP | high density lipoprotein binding protein | -0.0394491 |
| TRIM26 | tripartite motif containing 26 | -0.0393362 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0391487 |
| KIF21A | kinesin family member 21A | -0.0373327 |
| GPC3 | glypican 3 | -0.0358029 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0353354 |
| MT1G | metallothionein 1G | -0.0345604 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.034454 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0340509 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0340022 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0338287 |
| PERP | PERP, TP53 apoptosis effector | -0.0334571 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0332124 |
| RPLP0 | ribosomal protein, large, P0 | -0.0331285 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0329037 |
| APOA1 | apolipoprotein A-I | -0.0323826 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0321826 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0318338 |
| H1-0 | H1.0 linker histone | -0.0318065 |
| VEGFA | vascular endothelial growth factor A | -0.0313342 |
| APOE | apolipoprotein E | -0.0311949 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0309886 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0302148 |
| PKM | pyruvate kinase, muscle | -0.030066 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.030001 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0297011 |
| ASPH | aspartate beta-hydroxylase | -0.0292137 |
| RRBP1 | ribosome binding protein 1 | -0.0289321 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286641 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0285016 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0278066 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0272068 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0268825 |
| NABP1 | nucleic acid binding protein 1 | -0.0267843 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0265231 |
| AHNAK | AHNAK nucleoprotein | -0.0260295 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0259451 |
| BRD2 | bromodomain containing 2 | -0.0258904 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0258025 |
| PEG3 | paternally expressed 3 | -0.0256936 |
| DTNA | dystrobrevin, alpha | -0.0253712 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0252967 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0252631 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0252082 |
| CPE | carboxypeptidase E | -0.025166 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251247 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0249482 |
| LYZ | lysozyme | -0.0249228 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0238948 |
| HOMER1 | homer scaffolding protein 1 | -0.0238878 |
| ATP10A | ATPase, class V, type 10A | -0.0236949 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234611 |
| SERTAD2 | SERTA domain containing 2 | -0.0234495 |
| ACTG1 | actin gamma 1 | -0.0228069 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0227112 |
| FUS | FUS RNA binding protein | -0.0226822 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0224218 |
| GDF15 | growth differentiation factor 15 | -0.0223507 |
| FOXO3 | forkhead box O3 | -0.0223287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0222973 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0219107 |
| TOX3 | TOX high mobility group box family member 3 | -0.0218168 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0217117 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0215788 |
| RPL34 | ribosomal protein L34 | -0.0211618 |
| FABP1 | fatty acid binding protein 1, liver | -0.0210098 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0208711 |
