| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.291469 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.150063 |
| ERBIN | erbb2 interacting protein | 0.100781 |
| ZNF841 | zinc finger protein 841 | 0.0826284 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0793576 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0759215 |
| DST | dystonin | 0.074623 |
| ATP13A3 | ATPase type 13A3 | 0.0678509 |
| SET | SET nuclear proto-oncogene | 0.0673715 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0657646 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0647733 |
| TPM3 | tropomyosin 3 | 0.0644392 |
| CALR | calreticulin | 0.0635999 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.054152 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0540747 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0538766 |
| PODXL | podocalyxin-like | 0.0496724 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0481252 |
| RPL35A | ribosomal protein L35a | 0.0474574 |
| FLNB | filamin B, beta | 0.0451092 |
| CD44 | CD44 molecule (Indian blood group) | 0.0449711 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.042477 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.041184 |
| HLA-A | major histocompatibility complex, class I, A | 0.0408803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0393664 |
| RASA2 | RAS p21 protein activator 2 | 0.0380068 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0358217 |
| BCL2L1 | BCL2-like 1 | 0.035782 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0355235 |
| LDHA | lactate dehydrogenase A | 0.035073 |
| NUP58 | nucleoporin 58 | 0.0348767 |
| RPS3 | ribosomal protein S3 | 0.0331054 |
| NEK7 | NIMA-related kinase 7 | 0.032844 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0323189 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0321857 |
| PTK2 | protein tyrosine kinase 2 | 0.0320222 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0315586 |
| SMAD3 | SMAD family member 3 | 0.0313178 |
| ENO1 | enolase 1, (alpha) | 0.0311587 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0303983 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0300142 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0297345 |
| RPL26 | ribosomal protein L26 | 0.0295244 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0292899 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0290667 |
| RPL23 | ribosomal protein L23 | 0.0288489 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0285794 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.028514 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0283295 |
| RPS12 | ribosomal protein S12 | 0.0283046 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0282924 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.028156 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0278836 |
| TMSB10 | thymosin beta 10 | 0.0277633 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.026415 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0256755 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0247038 |
| MKI67 | marker of proliferation Ki-67 | 0.024466 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0242103 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0240817 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0238881 |
| DENND5A | DENN/MADD domain containing 5A | 0.0237403 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0237266 |
| ZNF148 | zinc finger protein 148 | 0.0235215 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02346 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0231573 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0230319 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0229952 |
| RPS2 | ribosomal protein S2 | 0.0229696 |
| OSMR | oncostatin M receptor | 0.0227334 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0224767 |
| MATR3 | matrin 3 | 0.02234 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0223311 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0223249 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.022088 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0215989 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0215299 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0214543 |
| ANGPTL4 | angiopoietin-like 4 | 0.0214324 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0212052 |
| KLC1 | kinesin light chain 1 | 0.0211385 |
| CFB | complement factor B | 0.0210853 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0208698 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0207457 |
| NUP153 | nucleoporin 153kDa | 0.0205855 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0202551 |
| ARRDC3 | arrestin domain containing 3 | 0.0202283 |
| CEP250 | centrosomal protein 250kDa | 0.020107 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0199813 |
| B2M | beta-2-microglobulin | 0.0199786 |
| GANAB | glucosidase, alpha; neutral AB | 0.0199759 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0197495 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0196694 |
| MSN | moesin | 0.0195731 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0195183 |
| RPL37A | ribosomal protein L37a | 0.0194323 |
| RPL30 | ribosomal protein L30 | 0.0193701 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0193359 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0190413 |
| FAT1 | FAT atypical cadherin 1 | 0.0188591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.250481 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222776 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.154046 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.118578 |
| FN1 | fibronectin 1 | -0.100256 |
| INTS6 | integrator complex subunit 6 | -0.0900184 |
| MAP1B | microtubule-associated protein 1B | -0.0894876 |
| DEK | DEK proto-oncogene | -0.0825273 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0790765 |
| HLA-B | major histocompatibility complex, class I, B | -0.0679328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0602707 |
| AHNAK | AHNAK nucleoprotein | -0.0579031 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0576823 |
| SQSTM1 | sequestosome 1 | -0.0558892 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0514292 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0511073 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0498451 |
| POTEF | POTE ankyrin domain family, member F | -0.044659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0444659 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0417329 |
| PLIN2 | perilipin 2 | -0.0408054 |
| CCND1 | cyclin D1 | -0.0405401 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0400378 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0395283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0387659 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0387487 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0367547 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.035607 |
| MTDH | metadherin | -0.035576 |
| CTSD | cathepsin D | -0.0355609 |
| CANX | calnexin | -0.0349361 |
| ACTG1 | actin gamma 1 | -0.0346049 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0341898 |
| GOLGB1 | golgin B1 | -0.0339541 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0332328 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0331426 |
| WASF2 | WAS protein family, member 2 | -0.0322688 |
| PKM | pyruvate kinase, muscle | -0.0320011 |
| RTN3 | reticulon 3 | -0.0312723 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310002 |
| MT1X | metallothionein 1X | -0.0306525 |
| NABP1 | nucleic acid binding protein 1 | -0.030144 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0299812 |
| HDLBP | high density lipoprotein binding protein | -0.0293092 |
| MAP4 | microtubule-associated protein 4 | -0.029007 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0289736 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0285698 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0282744 |
| ATXN1 | ataxin 1 | -0.0280413 |
| CDK6 | cyclin-dependent kinase 6 | -0.0279545 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.027918 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0279137 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.027867 |
| COPA | coatomer protein complex, subunit alpha | -0.0277679 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277574 |
| MMP12 | matrix metallopeptidase 12 | -0.0276687 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0275369 |
| SETX | senataxin | -0.0274101 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0270838 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0265554 |
| TKT | transketolase | -0.0263053 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0259784 |
| MYOF | myoferlin | -0.0259568 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0259295 |
| RPS6 | ribosomal protein S6 | -0.025921 |
| ARF4 | ADP-ribosylation factor 4 | -0.0256906 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0256327 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0255551 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0254174 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0253492 |
| FNIP1 | folliculin interacting protein 1 | -0.025174 |
| GOLGA4 | golgin A4 | -0.0250563 |
| CCDC80 | coiled-coil domain containing 80 | -0.0249386 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0247554 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0246104 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0245602 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0240944 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0240723 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0240574 |
| CAVIN1 | caveolae associated protein 1 | -0.0239462 |
| ZXDC | ZXD family zinc finger C | -0.0237907 |
| AFF4 | AF4/FMR2 family, member 4 | -0.023461 |
| CLIC4 | chloride intracellular channel 4 | -0.0233531 |
| S100A10 | S100 calcium binding protein A10 | -0.023255 |
| CUX1 | cut-like homeobox 1 | -0.0229966 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.022959 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0228582 |
| TPM4 | tropomyosin 4 | -0.0228546 |
| PLCB4 | phospholipase C, beta 4 | -0.0228334 |
| RPL28 | ribosomal protein L28 | -0.0223476 |
| POSTN | periostin, osteoblast specific factor | -0.0222241 |
| BBX | bobby sox homolog (Drosophila) | -0.0220241 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.021948 |
| EGR1 | early growth response 1 | -0.0217497 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0213858 |
| UBC | ubiquitin C | -0.0213179 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0212995 |
| TMEM263 | transmembrane protein 263 | -0.0211796 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0211442 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0210108 |