| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Chlorhexidine (diacetate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.138778 |
| TXNRD1 | thioredoxin reductase 1 | 0.124054 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.118464 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0945588 |
| CAPRIN2 | caprin family member 2 | 0.0920411 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0870194 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0773359 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0741648 |
| EZR | ezrin | 0.0708087 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0699974 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0678816 |
| RPS12 | ribosomal protein S12 | 0.0671987 |
| RPL37A | ribosomal protein L37a | 0.0668696 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0657428 |
| RPL35A | ribosomal protein L35a | 0.0656372 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0651741 |
| APP | amyloid beta (A4) precursor protein | 0.0639211 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0617901 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0606818 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0581101 |
| SMAD3 | SMAD family member 3 | 0.0577594 |
| RPL26 | ribosomal protein L26 | 0.0554483 |
| RAI1 | retinoic acid induced 1 | 0.0526471 |
| PYGL | phosphorylase, glycogen, liver | 0.0510145 |
| RPL23 | ribosomal protein L23 | 0.0506961 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0501467 |
| PTK2 | protein tyrosine kinase 2 | 0.0495986 |
| HLA-B | major histocompatibility complex, class I, B | 0.0492594 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0477767 |
| RPS3 | ribosomal protein S3 | 0.0473314 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0461512 |
| FMNL2 | formin-like 2 | 0.0454969 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0452609 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0452124 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0443419 |
| RPS19 | ribosomal protein S19 | 0.0436359 |
| ENO1 | enolase 1, (alpha) | 0.0428821 |
| RPS8 | ribosomal protein S8 | 0.0427746 |
| XPO6 | exportin 6 | 0.0426797 |
| YEATS2 | YEATS domain containing 2 | 0.0424813 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0423784 |
| RTN4 | reticulon 4 | 0.0422157 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0418629 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0413112 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0411498 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0406973 |
| RPL36 | ribosomal protein L36 | 0.0395987 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0395541 |
| RASA2 | RAS p21 protein activator 2 | 0.0391594 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0389709 |
| DENND5A | DENN/MADD domain containing 5A | 0.0387888 |
| RPL5 | ribosomal protein L5 | 0.0382841 |
| CMIP | c-Maf inducing protein | 0.0380941 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0377024 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0374123 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0371581 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0370063 |
| ANGPTL4 | angiopoietin-like 4 | 0.0368454 |
| ACTN1 | actinin, alpha 1 | 0.0365991 |
| LOXL2 | lysyl oxidase-like 2 | 0.0364319 |
| ARRDC3 | arrestin domain containing 3 | 0.0362948 |
| CEP170 | centrosomal protein 170kDa | 0.0360832 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0359977 |
| FLNB | filamin B, beta | 0.0356935 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0351121 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.034883 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0348204 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0342781 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0341802 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0337961 |
| BMERB1 | bMERB domain containing 1 | 0.0334893 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0331633 |
| WDR26 | WD repeat domain 26 | 0.0326638 |
| RPL36A | ribosomal protein L36a | 0.0325458 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.032525 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0323788 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0323339 |
| SEH1L | SEH1-like (S. cerevisiae) | 0.0321488 |
| SEPTIN9 | septin 9 | 0.031873 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0312905 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0310339 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0309503 |
| KLC1 | kinesin light chain 1 | 0.0308822 |
| PYGB | phosphorylase, glycogen; brain | 0.030659 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0306446 |
| PODXL | podocalyxin-like | 0.0306271 |
| FOXJ3 | forkhead box J3 | 0.0303638 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.030354 |
| CDK19 | cyclin-dependent kinase 19 | 0.0303165 |
| WDR43 | WD repeat domain 43 | 0.0302983 |
| ZNF292 | zinc finger protein 292 | 0.0302007 |
| TPM3 | tropomyosin 3 | 0.0301955 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0299289 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.029928 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0295815 |
| UCK2 | uridine-cytidine kinase 2 | 0.0293691 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.029292 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.029246 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0292141 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0291361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227213 |
| VIM | vimentin | -0.126811 |
| TP63 | tumor protein p63 | -0.0945316 |
| TXNIP | thioredoxin interacting protein | -0.0643034 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0520588 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0511156 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0509451 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0500188 |
| CADM2 | cell adhesion molecule 2 | -0.0498206 |
| LRRC49 | leucine rich repeat containing 49 | -0.0493775 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0487778 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0485855 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0471712 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0444253 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0417949 |
| PTMA | prothymosin, alpha | -0.0405738 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0404855 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0382375 |
| MT1E | metallothionein 1E | -0.0354418 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0346229 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0344628 |
| SP100 | SP100 nuclear antigen | -0.0332614 |
| INTS6 | integrator complex subunit 6 | -0.0332265 |
| TMSB4X | thymosin beta 4, X-linked | -0.0316678 |
| PLIN2 | perilipin 2 | -0.0312156 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0309769 |
| FTL | ferritin, light polypeptide | -0.0298376 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0291735 |
| HOMER1 | homer scaffolding protein 1 | -0.0282686 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0279892 |
| ANK2 | ankyrin 2, neuronal | -0.0273387 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.027111 |
| VCL | vinculin | -0.0270594 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0265037 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.02649 |
| H1-0 | H1.0 linker histone | -0.0263225 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.026044 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0247223 |
| HDAC9 | histone deacetylase 9 | -0.0243678 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.024339 |
| PLSCR1 | phospholipid scramblase 1 | -0.0238152 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0235005 |
| GNAS | GNAS complex locus | -0.0234707 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0233772 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0232194 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0231165 |
| SESN2 | sestrin 2 | -0.0225511 |
| POTEF | POTE ankyrin domain family, member F | -0.0224481 |
| EGR1 | early growth response 1 | -0.0223694 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0221669 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0221448 |
| ATF4 | activating transcription factor 4 | -0.0221289 |
| EPHA4 | EPH receptor A4 | -0.0215347 |
| KLHL24 | kelch-like family member 24 | -0.0210695 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0208697 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0202674 |
| FBXO11 | F-box protein 11 | -0.0200676 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0199161 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0197962 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0197425 |
| PHF3 | PHD finger protein 3 | -0.0197168 |
| TMEM135 | transmembrane protein 135 | -0.0197054 |
| MT1X | metallothionein 1X | -0.0195883 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0193674 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0193144 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0189075 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0188368 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0185862 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0185493 |
| CANX | calnexin | -0.0185322 |
| TUBB | tubulin, beta class I | -0.0181762 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0179751 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.017956 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.017924 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0177273 |
| HDLBP | high density lipoprotein binding protein | -0.0177232 |
| EREG | epiregulin | -0.0175546 |
| GLG1 | golgi glycoprotein 1 | -0.0172713 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0171942 |
| RTN3 | reticulon 3 | -0.0171424 |
| GOLGA4 | golgin A4 | -0.0169399 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0168934 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0165794 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0162291 |
| RPLP0 | ribosomal protein, large, P0 | -0.0161155 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0158242 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0157154 |
| NEK10 | NIMA-related kinase 10 | -0.0156135 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0153222 |
| RAB31 | RAB31, member RAS oncogene family | -0.0150876 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0150117 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0148138 |
| XPOT | exportin, tRNA | -0.0147926 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0147288 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0145026 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0144853 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0143574 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0142267 |
| JUN | jun proto-oncogene | -0.0142206 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0141766 |
