| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFIH1 | interferon induced with helicase C domain 1 | 0.17774 |
| AFF1 | AF4/FMR2 family, member 1 | 0.121098 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.119385 |
| DSCAM | Down syndrome cell adhesion molecule | 0.108181 |
| FAM13A | family with sequence similarity 13, member A | 0.107403 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.101777 |
| TXNRD1 | thioredoxin reductase 1 | 0.100847 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0898222 |
| KYNU | kynureninase | 0.0875719 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.087084 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0844373 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.0841367 |
| NDRG1 | N-myc downstream regulated 1 | 0.0796096 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0773793 |
| RAD51B | RAD51 paralog B | 0.0708435 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0674864 |
| LAMB3 | laminin, beta 3 | 0.0673697 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0667379 |
| JMJD1C | jumonji domain containing 1C | 0.0626768 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0619357 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0614696 |
| RIGI | RNA sensor RIG-I | 0.0607152 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0601314 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0601191 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0593948 |
| RNF149 | ring finger protein 149 | 0.0584316 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0583945 |
| GRB10 | growth factor receptor-bound protein 10 | 0.058159 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0557152 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0527152 |
| ANK2 | ankyrin 2, neuronal | 0.0518199 |
| ZNF292 | zinc finger protein 292 | 0.0517685 |
| IRS2 | insulin receptor substrate 2 | 0.0517251 |
| RPL26 | ribosomal protein L26 | 0.051294 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0502018 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0493434 |
| PTEN | phosphatase and tensin homolog | 0.0485033 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0484349 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.048285 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0476527 |
| VCL | vinculin | 0.0474248 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0466666 |
| SIK3 | SIK family kinase 3 | 0.0465548 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0462285 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.046124 |
| ABLIM1 | actin binding LIM protein 1 | 0.0460061 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0454752 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0448705 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0442331 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0435016 |
| USP53 | ubiquitin specific peptidase 53 | 0.0429141 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0424563 |
| SPAG9 | sperm associated antigen 9 | 0.0423393 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0422023 |
| TGM2 | transglutaminase 2 | 0.0420919 |
| GPHN | gephyrin | 0.0411021 |
| NPTN | neuroplastin | 0.0408504 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0402854 |
| ATG14 | autophagy related 14 | 0.0402552 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.040179 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0401081 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0399365 |
| DPEP2 | dipeptidase 2 | 0.0398755 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0395091 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0392878 |
| RPL35A | ribosomal protein L35a | 0.038528 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0383491 |
| ZNF704 | zinc finger protein 704 | 0.0381666 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381232 |
| WDR26 | WD repeat domain 26 | 0.0376434 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0375848 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0371621 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0370494 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0369603 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0367649 |
| NF1 | neurofibromin 1 | 0.0365612 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0364672 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362832 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0362169 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0361932 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0354893 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0354198 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0351508 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0349041 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0348984 |
| BBX | bobby sox homolog (Drosophila) | 0.0343872 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0341139 |
| XPO1 | exportin 1 | 0.0339984 |
| CDC27 | cell division cycle 27 | 0.0338264 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0337537 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0336131 |
| RIOK3 | RIO kinase 3 | 0.0334866 |
| RLF | rearranged L-myc fusion | 0.0332586 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0328621 |
| ACVR1 | activin A receptor, type I | 0.0328063 |
| PCNX1 | pecanex 1 | 0.0328035 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0326573 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0326343 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.032561 |
| DENND1A | DENN/MADD domain containing 1A | 0.032558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.176481 |
| KRT17 | keratin 17, type I | -0.0914063 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0905994 |
| ASPH | aspartate beta-hydroxylase | -0.0845086 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0752536 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0751573 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.074862 |
| ACTG1 | actin gamma 1 | -0.0729548 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0702314 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0692707 |
| VIM | vimentin | -0.0677358 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0650507 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0644965 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0642327 |
| HLA-B | major histocompatibility complex, class I, B | -0.061986 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0618157 |
| TMSB10 | thymosin beta 10 | -0.0613584 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0607801 |
| STC1 | stanniocalcin 1 | -0.0603822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0596558 |
| MMP1 | matrix metallopeptidase 1 | -0.0583894 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0581992 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.057687 |
| CDH13 | cadherin 13 | -0.0572017 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.055884 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.054455 |
| CANX | calnexin | -0.054272 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0536085 |
| RUNX1 | runt-related transcription factor 1 | -0.0529619 |
| MYO1E | myosin IE | -0.0513634 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0509297 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0506285 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0488557 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0477977 |
| IGF2 | insulin-like growth factor 2 | -0.0474217 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0471877 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.046908 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0467469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0466016 |
| FLNB | filamin B, beta | -0.0456434 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.045499 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0449966 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0446786 |
| AHNAK | AHNAK nucleoprotein | -0.0440525 |
| FRMD5 | FERM domain containing 5 | -0.0434707 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0434071 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0433967 |
| INHBA | inhibin, beta A | -0.0432033 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0431273 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0429505 |
| LAMC2 | laminin, gamma 2 | -0.0427365 |
| PARD3 | par-3 family cell polarity regulator | -0.0425504 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0424464 |
| EXT1 | exostosin glycosyltransferase 1 | -0.042058 |
| C1D | C1D nuclear receptor corepressor | -0.0418309 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0416478 |
| DSPP | dentin sialophosphoprotein | -0.0416016 |
| HMGA2 | high mobility group AT-hook 2 | -0.0407529 |
| RORA | RAR-related orphan receptor A | -0.0403824 |
| DENND4A | DENN/MADD domain containing 4A | -0.0402209 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0399061 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0396685 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0388046 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0385385 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0383451 |
| KIF13B | kinesin family member 13B | -0.0377938 |
| COL5A1 | collagen, type V, alpha 1 | -0.0376415 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0374763 |
| ITGB4 | integrin, beta 4 | -0.0372393 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0372356 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.036411 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0362263 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.036061 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0357775 |
| DST | dystonin | -0.0355871 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0353186 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | -0.035249 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.035218 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0347814 |
| GLIS3 | GLIS family zinc finger 3 | -0.0347308 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0347141 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0346004 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0343465 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0342383 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0337663 |
| MUC16 | mucin 16, cell surface associated | -0.0336646 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0335387 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0331252 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.033055 |
| HOMER1 | homer scaffolding protein 1 | -0.0328207 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0326594 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0326066 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0325252 |
| RBM47 | RNA binding motif protein 47 | -0.0324724 |
| RAB31 | RAB31, member RAS oncogene family | -0.0324592 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0317784 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0316464 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0316246 |
| CD9 | CD9 molecule | -0.0315726 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0313134 |
