| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Chlorhexidine (diacetate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.162334 |
| TPM3 | tropomyosin 3 | 0.0991042 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.092236 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0801667 |
| RAD51B | RAD51 paralog B | 0.0797746 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0789822 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.073784 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0691794 |
| RPS12 | ribosomal protein S12 | 0.0660378 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0649429 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0644978 |
| GRAMD1B | GRAM domain containing 1B | 0.0630706 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.062905 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0600357 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0569243 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0563183 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0542662 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0537518 |
| PCBP2 | poly(rC) binding protein 2 | 0.0514456 |
| RPL23 | ribosomal protein L23 | 0.0511117 |
| HSPA8 | heat shock 70kDa protein 8 | 0.050744 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0500689 |
| RPS3 | ribosomal protein S3 | 0.0481974 |
| RPL3 | ribosomal protein L3 | 0.0466815 |
| EXOC4 | exocyst complex component 4 | 0.0450129 |
| ANKRD11 | ankyrin repeat domain 11 | 0.044816 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0436978 |
| ATP11A | ATPase, class VI, type 11A | 0.0436075 |
| RPL35A | ribosomal protein L35a | 0.0413978 |
| MCL1 | myeloid cell leukemia 1 | 0.0412809 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.039428 |
| RPL37A | ribosomal protein L37a | 0.0382502 |
| PLEC | plectin | 0.0380413 |
| TMSB10 | thymosin beta 10 | 0.0365345 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0353434 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0353166 |
| RTN4 | reticulon 4 | 0.0350216 |
| CMIP | c-Maf inducing protein | 0.0348273 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0347628 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0344141 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.033969 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0338228 |
| SNX9 | sorting nexin 9 | 0.0337521 |
| IGF2 | insulin-like growth factor 2 | 0.0337474 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0328907 |
| ENO1 | enolase 1, (alpha) | 0.0328457 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0323311 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.031982 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.031899 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0314597 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0313766 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0312241 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0306085 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0304939 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0300567 |
| RPS27 | ribosomal protein S27 | 0.0296262 |
| YBX3 | Y box binding protein 3 | 0.029496 |
| RPL11 | ribosomal protein L11 | 0.0294162 |
| BRD4 | bromodomain containing 4 | 0.02917 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0287472 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0282826 |
| RPL5 | ribosomal protein L5 | 0.02801 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0279554 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0277219 |
| RPS7 | ribosomal protein S7 | 0.0272895 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0271569 |
| MKI67 | marker of proliferation Ki-67 | 0.0267773 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0267142 |
| SET | SET nuclear proto-oncogene | 0.0266318 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0265949 |
| YBX1 | Y box binding protein 1 | 0.0261995 |
| HMGA1 | high mobility group AT-hook 1 | 0.0259027 |
| CEP250 | centrosomal protein 250kDa | 0.0255889 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.025454 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0254028 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0252948 |
| UBE3A | ubiquitin protein ligase E3A | 0.0251002 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0250547 |
| TMEM41B | transmembrane protein 41B | 0.0249617 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0249588 |
| YAP1 | Yes-associated protein 1 | 0.0249166 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0248587 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0246194 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0245306 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0245083 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0244366 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0238437 |
| NCKAP1 | NCK-associated protein 1 | 0.0237796 |
| PNN | pinin, desmosome associated protein | 0.0236253 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0235996 |
| PRKCE | protein kinase C, epsilon | 0.0235637 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0235146 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0233249 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0232697 |
| GSE1 | Gse1 coiled-coil protein | 0.0232532 |
| ADAR | adenosine deaminase, RNA-specific | 0.0229366 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0228526 |
| RPS19 | ribosomal protein S19 | 0.0227637 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0227601 |
| RPS17 | ribosomal protein S17 | 0.0226872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.313284 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139475 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100881 |
| ACTG1 | actin gamma 1 | -0.0783511 |
| PTMA | prothymosin, alpha | -0.0616057 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0614756 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0564693 |
| CAVIN1 | caveolae associated protein 1 | -0.0536021 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0528217 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0513294 |
| VIM | vimentin | -0.0484895 |
| GNAS | GNAS complex locus | -0.0455102 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0434787 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0424934 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0413342 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0406361 |
| H1-0 | H1.0 linker histone | -0.0395849 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0382275 |
| CANX | calnexin | -0.0382234 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0375285 |
| RPLP0 | ribosomal protein, large, P0 | -0.0346826 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.034009 |
| AHNAK | AHNAK nucleoprotein | -0.0339984 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0332494 |
| SRP72 | signal recognition particle 72kDa | -0.0317621 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0312204 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0311741 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293997 |
| VCL | vinculin | -0.0293997 |
| TPM4 | tropomyosin 4 | -0.0293462 |
| TUBB | tubulin, beta class I | -0.0286549 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0283853 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0276563 |
| NF1 | neurofibromin 1 | -0.0274422 |
| RBM39 | RNA binding motif protein 39 | -0.0272124 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0268931 |
| TMEM263 | transmembrane protein 263 | -0.0268888 |
| COPA | coatomer protein complex, subunit alpha | -0.0268874 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0265928 |
| RYR3 | ryanodine receptor 3 | -0.0265771 |
| CCND1 | cyclin D1 | -0.0263298 |
| LRRC23 | leucine rich repeat containing 23 | -0.0263043 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0262385 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0259924 |
| HDLBP | high density lipoprotein binding protein | -0.0256661 |
| SEPTIN2 | septin 2 | -0.0256532 |
| CD2AP | CD2-associated protein | -0.0252271 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0251227 |
| HMGA2 | high mobility group AT-hook 2 | -0.0250076 |
| NBEAL1 | neurobeachin-like 1 | -0.0249504 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0247266 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0245851 |
| SRP54 | signal recognition particle 54kDa | -0.0238074 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0236096 |
| CDK12 | cyclin-dependent kinase 12 | -0.0230947 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229772 |
| RPS24 | ribosomal protein S24 | -0.0227956 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0226898 |
| S100A10 | S100 calcium binding protein A10 | -0.0225079 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0223975 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.022245 |
| TUBA1B | tubulin, alpha 1b | -0.0222135 |
| INTS6 | integrator complex subunit 6 | -0.0220048 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0214771 |
| ARF1 | ADP-ribosylation factor 1 | -0.0213377 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0213351 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0213237 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0213128 |
| RLF | rearranged L-myc fusion | -0.0211165 |
| IER3 | immediate early response 3 | -0.0210832 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0209689 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.020959 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0207293 |
| POTEF | POTE ankyrin domain family, member F | -0.0205772 |
| H3-3B | H3.3 histone B | -0.0198183 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0198114 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0197485 |
| DEK | DEK proto-oncogene | -0.0195743 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0194138 |
| UBB | ubiquitin B | -0.0193959 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0193013 |
| RPS15 | ribosomal protein S15 | -0.0192845 |
| USP34 | ubiquitin specific peptidase 34 | -0.0192816 |
| MORF4L2 | mortality factor 4 like 2 | -0.0192694 |
| ZNF217 | zinc finger protein 217 | -0.0192676 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0190414 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0190369 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0189477 |
| RPL38 | ribosomal protein L38 | -0.0185841 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0182402 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0180762 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0180543 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0179431 |
| RAB7A | RAB7A, member RAS oncogene family | -0.017926 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0178769 |
| WDR45B | WD repeat domain 45B | -0.017756 |
| RPS21 | ribosomal protein S21 | -0.0177251 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.017648 |
| SSH2 | slingshot protein phosphatase 2 | -0.0175264 |
| UBE4B | ubiquitination factor E4B | -0.017498 |
