| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.206424 |
| FN1 | fibronectin 1 | 0.18782 |
| LAMB3 | laminin, beta 3 | 0.173573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.132455 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.096981 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0903784 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0841626 |
| ARRDC3 | arrestin domain containing 3 | 0.0714973 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0703421 |
| TPM3 | tropomyosin 3 | 0.0690889 |
| CALR | calreticulin | 0.0688076 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0673342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0651283 |
| RPS12 | ribosomal protein S12 | 0.0616711 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0580064 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0573517 |
| LAMC2 | laminin, gamma 2 | 0.0564511 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0557444 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0545913 |
| ENO1 | enolase 1, (alpha) | 0.0545033 |
| RPL23 | ribosomal protein L23 | 0.0538699 |
| RPS3 | ribosomal protein S3 | 0.053455 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0518234 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0499073 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0482146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0460114 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0455744 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0427357 |
| LDHA | lactate dehydrogenase A | 0.0427082 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0424992 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0424296 |
| SET | SET nuclear proto-oncogene | 0.0398285 |
| PTK2 | protein tyrosine kinase 2 | 0.0380215 |
| RPS17 | ribosomal protein S17 | 0.0372961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367125 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0361865 |
| RPL35A | ribosomal protein L35a | 0.0360513 |
| EFNA5 | ephrin-A5 | 0.03592 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0353097 |
| RPL37A | ribosomal protein L37a | 0.0351475 |
| PLEC | plectin | 0.0351116 |
| FHIT | fragile histidine triad | 0.0350444 |
| NCKAP1 | NCK-associated protein 1 | 0.033768 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0336595 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0335334 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0328754 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0324371 |
| RPL3 | ribosomal protein L3 | 0.032436 |
| RPL9 | ribosomal protein L9 | 0.0315893 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0300824 |
| FBXO32 | F-box protein 32 | 0.0299918 |
| ADAR | adenosine deaminase, RNA-specific | 0.0295318 |
| RPL5 | ribosomal protein L5 | 0.0294902 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0293042 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0292113 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0290286 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0289794 |
| HLA-A | major histocompatibility complex, class I, A | 0.0287912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0282911 |
| FAM13A | family with sequence similarity 13, member A | 0.0282068 |
| HMGB2 | high mobility group box 2 | 0.0280346 |
| DST | dystonin | 0.0279523 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0276203 |
| ASPH | aspartate beta-hydroxylase | 0.0274552 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.027268 |
| CCNY | cyclin Y | 0.0270818 |
| CTSB | cathepsin B | 0.0266833 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0266198 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02638 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0260736 |
| PEG10 | paternally expressed 10 | 0.0260504 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0257074 |
| RPS7 | ribosomal protein S7 | 0.0256677 |
| HLA-B | major histocompatibility complex, class I, B | 0.0253303 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.025084 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0249797 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0247581 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0243789 |
| TPR | translocated promoter region, nuclear basket protein | 0.0242073 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0240264 |
| TMSB10 | thymosin beta 10 | 0.0240169 |
| ANXA11 | annexin A11 | 0.023952 |
| SMYD3 | SET and MYND domain containing 3 | 0.0237166 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.023678 |
| RPS8 | ribosomal protein S8 | 0.0235728 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0232405 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0229545 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0229405 |
| RPL11 | ribosomal protein L11 | 0.022846 |
| APP | amyloid beta (A4) precursor protein | 0.0227949 |
| STEAP4 | STEAP family member 4 | 0.0224807 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0221003 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0220249 |
| KRT8 | keratin 8, type II | 0.021892 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0214343 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0214275 |
| RPL6 | ribosomal protein L6 | 0.0212889 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0211284 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0209828 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.020933 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.254374 |
| ACTG1 | actin gamma 1 | -0.131183 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117304 |
| MT2A | metallothionein 2A | -0.11673 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.105747 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0990876 |
| FTL | ferritin, light polypeptide | -0.0832723 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0790506 |
| S100A10 | S100 calcium binding protein A10 | -0.0648538 |
| PTMA | prothymosin, alpha | -0.0617217 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0585702 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0577068 |
| COPA | coatomer protein complex, subunit alpha | -0.0561906 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0549271 |
| S100A6 | S100 calcium binding protein A6 | -0.0541859 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0532062 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0519242 |
| TMEM263 | transmembrane protein 263 | -0.0500135 |
| RPS6 | ribosomal protein S6 | -0.0475432 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0462289 |
| GNAS | GNAS complex locus | -0.0461658 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0456619 |
| MT1E | metallothionein 1E | -0.0448906 |
| LMO7 | LIM domain 7 | -0.0447698 |
| EGR1 | early growth response 1 | -0.0437475 |
| UBC | ubiquitin C | -0.0432161 |
| TMSB4X | thymosin beta 4, X-linked | -0.0428234 |
| POTEF | POTE ankyrin domain family, member F | -0.0397462 |
| CCND1 | cyclin D1 | -0.0396876 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0395832 |
| ANXA2 | annexin A2 | -0.0391617 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0388964 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0385835 |
| RPS23 | ribosomal protein S23 | -0.0384786 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0382799 |
| PKM | pyruvate kinase, muscle | -0.0378472 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0373198 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0368592 |
| RHOA | ras homolog family member A | -0.0356634 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0353568 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0347479 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0345499 |
| CD2AP | CD2-associated protein | -0.0338653 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0333436 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327241 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0326966 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326833 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0325893 |
| WASF2 | WAS protein family, member 2 | -0.0320883 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320831 |
| RPL14 | ribosomal protein L14 | -0.0318249 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0317406 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0316702 |
| RNF145 | ring finger protein 145 | -0.0310028 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0308427 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0308383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0308358 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0300415 |
| RPL32 | ribosomal protein L32 | -0.0297173 |
| MYO6 | myosin VI | -0.0284761 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0284094 |
| FBXO11 | F-box protein 11 | -0.0283606 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0283509 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0282487 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0282368 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0280185 |
| ERBIN | erbb2 interacting protein | -0.0278767 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0278475 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0277947 |
| RPL28 | ribosomal protein L28 | -0.027546 |
| NABP1 | nucleic acid binding protein 1 | -0.0273578 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.027233 |
| MED13 | mediator complex subunit 13 | -0.0272238 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0269315 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0267755 |
| RPS24 | ribosomal protein S24 | -0.0267751 |
| TJP1 | tight junction protein 1 | -0.0267253 |
| RRBP1 | ribosome binding protein 1 | -0.0267109 |
| RASAL2 | RAS protein activator like 2 | -0.0265919 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0263713 |
| HDAC9 | histone deacetylase 9 | -0.0263229 |
| G0S2 | G0/G1 switch 2 | -0.0262899 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0261811 |
| SP100 | SP100 nuclear antigen | -0.0257841 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0254697 |
| RBM39 | RNA binding motif protein 39 | -0.0254161 |
| SEC24D | SEC24 family member D | -0.0252994 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0250733 |
| OXSR1 | oxidative stress responsive 1 | -0.0250335 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0250183 |
| INTS6 | integrator complex subunit 6 | -0.0247998 |
| RPL8 | ribosomal protein L8 | -0.0247028 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0246531 |
| CERT1 | ceramide transporter 1 | -0.0245136 |
| CCNI | cyclin I | -0.0243402 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0242762 |
| USP3 | ubiquitin specific peptidase 3 | -0.0242443 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0234305 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0232448 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0231858 |
