| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.152271 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.138859 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125333 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.124201 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.124101 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.112316 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.110807 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.109305 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.109004 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.108155 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.107228 |
| HELZ | helicase with zinc finger | 0.105954 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.105199 |
| MED27 | mediator complex subunit 27 | 0.100271 |
| ANKRD17 | ankyrin repeat domain 17 | 0.094265 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0932596 |
| WDR45B | WD repeat domain 45B | 0.0914807 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0862758 |
| NDRG1 | N-myc downstream regulated 1 | 0.084223 |
| SPAG9 | sperm associated antigen 9 | 0.0812293 |
| PAPOLA | poly(A) polymerase alpha | 0.0811916 |
| PCM1 | pericentriolar material 1 | 0.0810285 |
| CDH13 | cadherin 13 | 0.0808723 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0790037 |
| TPR | translocated promoter region, nuclear basket protein | 0.0779566 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0744679 |
| DTNA | dystrobrevin, alpha | 0.0744405 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0733385 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0695788 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0684018 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0669094 |
| SQSTM1 | sequestosome 1 | 0.0621256 |
| DSCAM | Down syndrome cell adhesion molecule | 0.061545 |
| FMN1 | formin 1 | 0.0604545 |
| MED13L | mediator complex subunit 13-like | 0.0602486 |
| LSAMP | limbic system-associated membrane protein | 0.0593314 |
| CLTC | clathrin, heavy chain (Hc) | 0.0590333 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.057821 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0571948 |
| CADM2 | cell adhesion molecule 2 | 0.0552168 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0547178 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.05339 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0516654 |
| IGF2 | insulin-like growth factor 2 | 0.0501429 |
| EGR1 | early growth response 1 | 0.0498514 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0483914 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0483662 |
| MYO10 | myosin X | 0.0480551 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0480319 |
| DST | dystonin | 0.0471667 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0470064 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0444631 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0443956 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0443301 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0440995 |
| VMP1 | vacuole membrane protein 1 | 0.0438828 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0428927 |
| MATR3 | matrin 3 | 0.0421114 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0417763 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0399342 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0396171 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0392642 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0376738 |
| FNIP1 | folliculin interacting protein 1 | 0.0374424 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0365661 |
| GPHN | gephyrin | 0.0364563 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.03633 |
| INHBA | inhibin, beta A | 0.0352211 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0339253 |
| TXNRD1 | thioredoxin reductase 1 | 0.0327987 |
| BPTF | bromodomain PHD finger transcription factor | 0.0324471 |
| LYST | lysosomal trafficking regulator | 0.0305397 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0302746 |
| VIM | vimentin | 0.0295052 |
| CEP170 | centrosomal protein 170kDa | 0.029288 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0288891 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0280564 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0276338 |
| SYT1 | synaptotagmin I | 0.0275153 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0252547 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251162 |
| PDE8A | phosphodiesterase 8A | 0.0247037 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.024518 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0237986 |
| GLG1 | golgi glycoprotein 1 | 0.0236346 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0223625 |
| RTN4 | reticulon 4 | 0.0219143 |
| NAV2 | neuron navigator 2 | 0.0217443 |
| SETD5 | SET domain containing 5 | 0.0215545 |
| OXR1 | oxidation resistance 1 | 0.021226 |
| INTS6 | integrator complex subunit 6 | 0.0205491 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0205202 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0204129 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0199016 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0195952 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0193127 |
| SEPTIN9 | septin 9 | 0.0185974 |
| RPL23 | ribosomal protein L23 | 0.0184774 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0183846 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0182885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.211319 |
| EGFR | epidermal growth factor receptor | -0.170887 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.105542 |
| EFNA5 | ephrin-A5 | -0.103606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.102383 |
| FN1 | fibronectin 1 | -0.0974418 |
| VCL | vinculin | -0.0965644 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0947069 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0906228 |
| PKM | pyruvate kinase, muscle | -0.085389 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0850648 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0845714 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0839658 |
| FAM13A | family with sequence similarity 13, member A | -0.0793551 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.078086 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0775107 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0765532 |
| MYOF | myoferlin | -0.0763938 |
| SLTM | SAFB-like, transcription modulator | -0.0762673 |
| POTEF | POTE ankyrin domain family, member F | -0.0719996 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0703507 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0693232 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0647084 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0632948 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0602532 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0594812 |
| TMSB10 | thymosin beta 10 | -0.0581813 |
| FMNL2 | formin-like 2 | -0.0574367 |
| ASPH | aspartate beta-hydroxylase | -0.0562459 |
| OSMR | oncostatin M receptor | -0.0560796 |
| ACTG1 | actin gamma 1 | -0.0551961 |
| RAD51B | RAD51 paralog B | -0.0550156 |
| GLIS3 | GLIS family zinc finger 3 | -0.053835 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0528002 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0521124 |
| FLNB | filamin B, beta | -0.0515066 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0511999 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0511251 |
| SMYD3 | SET and MYND domain containing 3 | -0.0507958 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0489975 |
| RPLP1 | ribosomal protein, large, P1 | -0.0488973 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0481281 |
| PDE10A | phosphodiesterase 10A | -0.0479259 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.04791 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0476338 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0474769 |
| PTMA | prothymosin, alpha | -0.0458369 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0457549 |
| SBF2 | SET binding factor 2 | -0.0443084 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0429686 |
| RPS8 | ribosomal protein S8 | -0.0420931 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0412659 |
| ZNF292 | zinc finger protein 292 | -0.0402761 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0397508 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0382041 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0377052 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0369506 |
| TMEM165 | transmembrane protein 165 | -0.0368603 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0360637 |
| OGA | O-GlcNAcase | -0.0354016 |
| MYO6 | myosin VI | -0.0352156 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0342535 |
| CD44 | CD44 molecule (Indian blood group) | -0.0329342 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0311909 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0303372 |
| SMAD3 | SMAD family member 3 | -0.0300277 |
| RPS3 | ribosomal protein S3 | -0.0288851 |
| B2M | beta-2-microglobulin | -0.0288224 |
| NFIA | nuclear factor I/A | -0.0271857 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0261686 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0256535 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.025253 |
| YBX3 | Y box binding protein 3 | -0.0252062 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0241055 |
| GOLGA4 | golgin A4 | -0.0235694 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0233635 |
| HDLBP | high density lipoprotein binding protein | -0.0231252 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.022801 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0217171 |
| USP34 | ubiquitin specific peptidase 34 | -0.0213291 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0199796 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0190776 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0184049 |
| MCL1 | myeloid cell leukemia 1 | -0.0175396 |
| RPL35A | ribosomal protein L35a | -0.0175174 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0165537 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0163276 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0161815 |
| RAB10 | RAB10, member RAS oncogene family | -0.0160558 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0159982 |
| ANXA2 | annexin A2 | -0.0158366 |
| ARRDC3 | arrestin domain containing 3 | -0.0154016 |
| MT2A | metallothionein 2A | -0.0152496 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0150454 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0146374 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0141065 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0136785 |
| ZNF609 | zinc finger protein 609 | -0.0135947 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0135342 |
| RPS6 | ribosomal protein S6 | -0.0131799 |
