Chlorhexidine (diacetate)_RPMI-7951 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Chlorhexidine (diacetate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Chlorhexidine (diacetate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYH9 myosin, heavy chain 9, non-muscle 0.122094
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.117812
IFI6 interferon, alpha-inducible protein 6 0.104997
ASPH aspartate beta-hydroxylase 0.100762
CD44 CD44 molecule (Indian blood group) 0.0983495
NAMPT nicotinamide phosphoribosyltransferase 0.0929727
B2M beta-2-microglobulin 0.091509
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0807096
WWTR1 WW domain containing transcription regulator 1 0.0780123
ZNF292 zinc finger protein 292 0.0764201
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0720307
FLNB filamin B, beta 0.0708689
ANGPTL4 angiopoietin-like 4 0.0702063
FAM20C family with sequence similarity 20, member C 0.0667676
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0663774
PTK2 protein tyrosine kinase 2 0.06583
PSD3 pleckstrin and Sec7 domain containing 3 0.0625207
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0610269
KLF7 Kruppel-like factor 7 (ubiquitous) 0.060123
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0587183
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.0585721
LDHA lactate dehydrogenase A 0.0559299
ENO1 enolase 1, (alpha) 0.0542899
APCDD1L adenomatosis polyposis coli down-regulated 1-like 0.0523686
NDRG1 N-myc downstream regulated 1 0.0515077
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0502561
STC1 stanniocalcin 1 0.050108
COL7A1 collagen, type VII, alpha 1 0.0498363
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0496846
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0495016
YEATS2 YEATS domain containing 2 0.0487756
TPM3 tropomyosin 3 0.0486491
AFDN afadin, adherens junction formation factor 0.0479847
HLA-B major histocompatibility complex, class I, B 0.0479771
HLA-A major histocompatibility complex, class I, A 0.0467421
KMT2E lysine (K)-specific methyltransferase 2E 0.0466022
ZNF148 zinc finger protein 148 0.0463655
SPRED1 sprouty-related, EVH1 domain containing 1 0.0455489
RPL23 ribosomal protein L23 0.0450722
ATP13A3 ATPase type 13A3 0.0448981
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.0440666
CEMIP cell migration inducing protein, hyaluronan binding 0.043359
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0431071
AKAP12 A kinase (PRKA) anchor protein 12 0.0422747
PGK1 phosphoglycerate kinase 1 0.0422661
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0416666
RTN4 reticulon 4 0.0413377
SET SET nuclear proto-oncogene 0.0411498
PHC2 polyhomeotic homolog 2 (Drosophila) 0.0403321
ANLN anillin, actin binding protein 0.0393538
NCKAP1 NCK-associated protein 1 0.0384543
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0377561
RPS12 ribosomal protein S12 0.0368214
NAV2 neuron navigator 2 0.0365025
SMAD3 SMAD family member 3 0.0364977
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0362577
RPL35A ribosomal protein L35a 0.0361763
LPP LIM domain containing preferred translocation partner in lipoma 0.0361492
IFI44 interferon-induced protein 44 0.0360477
TFPI2 tissue factor pathway inhibitor 2 0.0357115
JARID2 jumonji, AT rich interactive domain 2 0.0354789
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 0.0349637
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0344259
FAT1 FAT atypical cadherin 1 0.0343363
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0343231
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0342237
YME1L1 YME1-like 1 ATPase 0.0335473
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0334943
SFPQ splicing factor proline/glutamine-rich 0.0334663
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0334026
UBE3A ubiquitin protein ligase E3A 0.0332586
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0327024
RPS17 ribosomal protein S17 0.0326438
PTPRF protein tyrosine phosphatase, receptor type, F 0.0324601
WAC WW domain containing adaptor with coiled-coil 0.0323531
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0323047
GYS1 glycogen synthase 1 (muscle) 0.0322147
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0320701
HIPK2 homeodomain interacting protein kinase 2 0.0316806
SMOX spermine oxidase 0.0316707
RPL26 ribosomal protein L26 0.0311441
DNAAF9 dynein axonemal assembly factor 9 0.0309998
MTSS1 metastasis suppressor 1 0.0309943
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0307136
HMGA2 high mobility group AT-hook 2 0.0306632
RASA3 RAS p21 protein activator 3 0.0306426
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0304071
IFI44L interferon-induced protein 44-like 0.0303919
SETBP1 SET binding protein 1 0.0303235
SVIL supervillin 0.0302765
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0301385
DST dystonin 0.0296599
SRRM2 serine/arginine repetitive matrix 2 0.0296428
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.0290716
KLF6 Kruppel-like factor 6 0.029011
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0287403
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0283436
PTBP2 polypyrimidine tract binding protein 2 0.0281334
PDIA6 protein disulfide isomerase family A, member 6 0.0280449
CDC73 cell division cycle 73 0.028031

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.266231
VIM vimentin -0.221283
FN1 fibronectin 1 -0.188927
COL1A1 collagen, type I, alpha 1 -0.131686
MT2A metallothionein 2A -0.125878
COL1A2 collagen, type I, alpha 2 -0.091954
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0842982
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0750262
PKM pyruvate kinase, muscle -0.0690273
CDH13 cadherin 13 -0.0665416
TPM4 tropomyosin 4 -0.0627973
POTEF POTE ankyrin domain family, member F -0.061799
RAB7A RAB7A, member RAS oncogene family -0.0592915
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0498601
IER3 immediate early response 3 -0.0485287
COL6A1 collagen, type VI, alpha 1 -0.0481878
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0468331
MMP12 matrix metallopeptidase 12 -0.0466117
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0452948
HDLBP high density lipoprotein binding protein -0.0437008
NAV1 neuron navigator 1 -0.0431749
FTL ferritin, light polypeptide -0.0422648
ARL4C ADP-ribosylation factor-like 4C -0.0405209
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0389955
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0384384
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0371369
VCAN versican -0.0366804
PTMA prothymosin, alpha -0.0358003
IGFBP5 insulin-like growth factor binding protein 5 -0.0348646
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0341706
RPL28 ribosomal protein L28 -0.0336429
TENT5A terminal nucleotidyltransferase 5A -0.0324601
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0322127
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0314624
SLIT2 slit homolog 2 (Drosophila) -0.0307967
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0307579
BHLHE40 basic helix-loop-helix family, member e40 -0.0303482
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0294942
LMAN1 lectin, mannose-binding, 1 -0.0294707
ZBTB20 zinc finger and BTB domain containing 20 -0.0294625
SERF2 small EDRK-rich factor 2 -0.0294543
SEC31A SEC31 homolog A (S. cerevisiae) -0.0291728
TPM1 tropomyosin 1 (alpha) -0.0288483
PDIA3 protein disulfide isomerase family A, member 3 -0.0284777
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0282941
FHIT fragile histidine triad -0.0276551
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0273018
ITGA1 integrin, alpha 1 -0.0268301
GNAS GNAS complex locus -0.0267149
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0264885
LPCAT2 lysophosphatidylcholine acyltransferase 2 -0.0264771
SHISA5 shisa family member 5 -0.0262529
TTC3 tetratricopeptide repeat domain 3 -0.0262459
AGO3 argonaute RISC catalytic component 3 -0.0259376
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0258545
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0257642
BTG1 B-cell translocation gene 1, anti-proliferative -0.0256438
RPLP2 ribosomal protein, large, P2 -0.0254496
WASF2 WAS protein family, member 2 -0.0253703
DENND4A DENN/MADD domain containing 4A -0.0251308
EIF1 eukaryotic translation initiation factor 1 -0.0249423
COLEC10 collectin sub-family member 10 (C-type lectin) -0.0249276
LOX lysyl oxidase -0.0248487
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0244889
HILPDA hypoxia inducible lipid droplet-associated -0.0241456
SRP54 signal recognition particle 54kDa -0.0241053
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0240947
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0240435
ZBTB38 zinc finger and BTB domain containing 38 -0.023983
CALD1 caldesmon 1 -0.023496
NREP neuronal regeneration related protein -0.0233819
PDLIM5 PDZ and LIM domain 5 -0.0233747
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0232356
IKBIP IKBKB interacting protein -0.0228303
TMEM263 transmembrane protein 263 -0.0226628
THY1 Thy-1 cell surface antigen -0.0226451
TAPBP TAP binding protein (tapasin) -0.0225742
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -0.0225228
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0224401
ADM adrenomedullin -0.0223857
CA12 carbonic anhydrase XII -0.0223386
VDAC1 voltage-dependent anion channel 1 -0.0222641
INTS6 integrator complex subunit 6 -0.0222303
FBXL7 F-box and leucine-rich repeat protein 7 -0.0221195
KDM5B lysine (K)-specific demethylase 5B -0.022115
FBN1 fibrillin 1 -0.022048
COL6A2 collagen, type VI, alpha 2 -0.0219974
NABP1 nucleic acid binding protein 1 -0.0216978
RRBP1 ribosome binding protein 1 -0.0216726
ACTG1 actin gamma 1 -0.0213151
SNX14 sorting nexin 14 -0.0210611
SEPTIN2 septin 2 -0.020785
SLC38A2 solute carrier family 38, member 2 -0.0206082
CALU calumenin -0.0205946
TGFB1 transforming growth factor, beta 1 -0.0204141
MTDH metadherin -0.0201768
FLOT1 flotillin 1 -0.0200901
TNS3 tensin 3 -0.0200233
HIP1 huntingtin interacting protein 1 -0.0199363
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0197223