| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Chlorhexidine (diacetate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.341424 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0598044 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0471676 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0434899 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0424132 |
| ZNF292 | zinc finger protein 292 | 0.039882 |
| FAT1 | FAT atypical cadherin 1 | 0.0397865 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0397652 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0396297 |
| AOPEP | aminopeptidase O (putative) | 0.0393584 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.038518 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0360789 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0341283 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0328796 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0313364 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0307913 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0306949 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0301274 |
| NCKAP1 | NCK-associated protein 1 | 0.0292926 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0287538 |
| CADM1 | cell adhesion molecule 1 | 0.0286692 |
| RIT2 | Ras-like without CAAX 2 | 0.0286246 |
| RPS12 | ribosomal protein S12 | 0.02707 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0268976 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0267761 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0260847 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0259412 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0258326 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0247744 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0243217 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0241942 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0239018 |
| FOXN3 | forkhead box N3 | 0.023826 |
| XPO1 | exportin 1 | 0.0237142 |
| IRS2 | insulin receptor substrate 2 | 0.0233089 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0230149 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0229547 |
| MATR3 | matrin 3 | 0.0228887 |
| NCAM1 | neural cell adhesion molecule 1 | 0.02278 |
| CENPF | centromere protein F, 350/400kDa | 0.0227321 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0227008 |
| SET | SET nuclear proto-oncogene | 0.0225821 |
| VGF | VGF nerve growth factor inducible | 0.0224795 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0223029 |
| SFPQ | splicing factor proline/glutamine-rich | 0.022193 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0221394 |
| MTMR7 | myotubularin related protein 7 | 0.0218657 |
| MKI67 | marker of proliferation Ki-67 | 0.0218314 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0217472 |
| TMEM255B | transmembrane protein 255B | 0.0214958 |
| PARD3 | par-3 family cell polarity regulator | 0.021447 |
| GRAMD4 | GRAM domain containing 4 | 0.0213078 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0212254 |
| RTN4 | reticulon 4 | 0.0211617 |
| WWOX | WW domain containing oxidoreductase | 0.0209954 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0206763 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0206655 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0205198 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0203859 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.02035 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0202364 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0201473 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0200871 |
| CNBD1 | cyclic nucleotide binding domain containing 1 | 0.0198536 |
| ANKRD10 | ankyrin repeat domain 10 | 0.019722 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0196344 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0195316 |
| ANLN | anillin, actin binding protein | 0.0194989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0194092 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0192388 |
| GSE1 | Gse1 coiled-coil protein | 0.019174 |
| RPS7 | ribosomal protein S7 | 0.0191691 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0191016 |
| RPL26 | ribosomal protein L26 | 0.0190174 |
| TMEM178B | transmembrane protein 178B | 0.0188039 |
| FANCL | Fanconi anemia, complementation group L | 0.0185266 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0183789 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0183721 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0181326 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0181159 |
| NUP58 | nucleoporin 58 | 0.0180894 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.018014 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0178821 |
| KANTR | KDM5C adjacent non-coding transcript | 0.0178388 |
| MT2A | metallothionein 2A | 0.0176282 |
| RFLNA | refilin A | 0.0176251 |
| STK24 | serine/threonine kinase 24 | 0.0175331 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0175231 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0173793 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0173611 |
| AFDN | afadin, adherens junction formation factor | 0.0173009 |
| SPAG5 | sperm associated antigen 5 | 0.017159 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0169455 |
| ECT2 | epithelial cell transforming 2 | 0.0169028 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0168446 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.0167132 |
| PRKD1 | protein kinase D1 | 0.0166192 |
| PDS5B | PDS5 cohesin associated factor B | 0.0162484 |
| RPL23 | ribosomal protein L23 | 0.0161006 |
| CDK17 | cyclin-dependent kinase 17 | 0.0160977 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123083 |
| MCL1 | myeloid cell leukemia 1 | -0.109027 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0971052 |
| EGR1 | early growth response 1 | -0.0926404 |
| STC1 | stanniocalcin 1 | -0.0898699 |
| NRG1 | neuregulin 1 | -0.0848802 |
| GPC6 | glypican 6 | -0.0769945 |
| ACTG1 | actin gamma 1 | -0.0763332 |
| MAP1B | microtubule-associated protein 1B | -0.0755385 |
| PTMA | prothymosin, alpha | -0.0737837 |
| CPE | carboxypeptidase E | -0.069576 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0659288 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0634945 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.059043 |
| INHBA | inhibin, beta A | -0.0571311 |
| SNTG1 | syntrophin, gamma 1 | -0.0561612 |
| ESRRG | estrogen-related receptor gamma | -0.0554075 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0553559 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0509801 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.050669 |
| SCG2 | secretogranin II | -0.0504135 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0487264 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0481688 |
| PTCHD4 | patched domain containing 4 | -0.0479377 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450737 |
| KIF26B | kinesin family member 26B | -0.0449686 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0442282 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0439762 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0421935 |
| TOP1 | topoisomerase (DNA) I | -0.0420903 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0412109 |
| ENO1 | enolase 1, (alpha) | -0.0410008 |
| NAV2 | neuron navigator 2 | -0.0404171 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0401137 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0398333 |
| CANX | calnexin | -0.0371184 |
| HOMER1 | homer scaffolding protein 1 | -0.0370144 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0369135 |
| GPC5 | glypican 5 | -0.036843 |
| TMSB4X | thymosin beta 4, X-linked | -0.0365085 |
| CALCA | calcitonin-related polypeptide alpha | -0.0361172 |
| TPM4 | tropomyosin 4 | -0.0353949 |
| EPHA6 | EPH receptor A6 | -0.0345277 |
| SETX | senataxin | -0.0342486 |
| PKM | pyruvate kinase, muscle | -0.0339756 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0333496 |
| CHGA | chromogranin A | -0.0332545 |
| JUN | jun proto-oncogene | -0.03322 |
| CHGB | chromogranin B | -0.0331985 |
| NANOS1 | nanos homolog 1 (Drosophila) | -0.0326361 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0325618 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0324847 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0323527 |
| TENM1 | teneurin transmembrane protein 1 | -0.0318028 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0314332 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0310438 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0309871 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.030729 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0306399 |
| HM13 | histocompatibility (minor) 13 | -0.0302699 |
| NELL1 | NEL-like 1 (chicken) | -0.0302664 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0302136 |
| NBEA | neurobeachin | -0.0297323 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0293902 |
| POTEF | POTE ankyrin domain family, member F | -0.028742 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0284256 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0278224 |
| INTS6 | integrator complex subunit 6 | -0.0277712 |
| GOLGB1 | golgin B1 | -0.0273514 |
| RORA | RAR-related orphan receptor A | -0.0271084 |
| ARFGEF3 | ARFGEF family member 3 | -0.0269681 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.02651 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0262642 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0262044 |
| FNDC3A | fibronectin type III domain containing 3A | -0.025999 |
| MAP7 | microtubule-associated protein 7 | -0.0254683 |
| SMYD3 | SET and MYND domain containing 3 | -0.0245605 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0238482 |
| FN1 | fibronectin 1 | -0.0234889 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0230949 |
| COPA | coatomer protein complex, subunit alpha | -0.0230919 |
| GNAS | GNAS complex locus | -0.0230674 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0228967 |
| ATF6 | activating transcription factor 6 | -0.0220692 |
| UBB | ubiquitin B | -0.0219241 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.021836 |
| SRP54 | signal recognition particle 54kDa | -0.0216506 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0214613 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0214328 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0214263 |
| ZNF638 | zinc finger protein 638 | -0.0213032 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0212434 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0210739 |
| FAM13A | family with sequence similarity 13, member A | -0.0210686 |
| DENND4A | DENN/MADD domain containing 4A | -0.0210248 |
| ONECUT2 | one cut homeobox 2 | -0.0208949 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0206816 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0206631 |
| VMP1 | vacuole membrane protein 1 | -0.0206444 |
| CDK13 | cyclin-dependent kinase 13 | -0.0203695 |