| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Chlorhexidine (diacetate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Chlorhexidine (diacetate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.123561 |
| FNDC3B | fibronectin type III domain containing 3B | 0.113498 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0768455 |
| DST | dystonin | 0.0756319 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0681647 |
| HDAC9 | histone deacetylase 9 | 0.0673587 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0663385 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0651015 |
| FLNA | filamin A, alpha | 0.0597269 |
| TPM3 | tropomyosin 3 | 0.0588213 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0583449 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0572185 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0551685 |
| AFDN | afadin, adherens junction formation factor | 0.0511405 |
| RPL3 | ribosomal protein L3 | 0.0503544 |
| RPS12 | ribosomal protein S12 | 0.049424 |
| RPS3 | ribosomal protein S3 | 0.046996 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0467632 |
| FMNL2 | formin-like 2 | 0.0461912 |
| MSN | moesin | 0.0453464 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0453151 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.044814 |
| EP300 | E1A binding protein p300 | 0.0445251 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0427242 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0425055 |
| FLNB | filamin B, beta | 0.0424996 |
| PTK2 | protein tyrosine kinase 2 | 0.0421426 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0417246 |
| NDRG1 | N-myc downstream regulated 1 | 0.0406592 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0383453 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0375939 |
| NAV2 | neuron navigator 2 | 0.0374621 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0371514 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370869 |
| NCKAP1 | NCK-associated protein 1 | 0.0370756 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0367695 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0357132 |
| MCL1 | myeloid cell leukemia 1 | 0.0356155 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0353537 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0352623 |
| CORO1C | coronin, actin binding protein, 1C | 0.0352213 |
| ENO1 | enolase 1, (alpha) | 0.0344063 |
| TXNRD1 | thioredoxin reductase 1 | 0.0342304 |
| RUNX1 | runt-related transcription factor 1 | 0.0340687 |
| PLEC | plectin | 0.0338141 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0334568 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0333131 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0331941 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0327613 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0327467 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0326086 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0323988 |
| PRELID2 | PRELI domain containing 2 | 0.031874 |
| TUSC3 | tumor suppressor candidate 3 | 0.0314274 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0307509 |
| CTTN | cortactin | 0.0303042 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0300765 |
| CDK19 | cyclin-dependent kinase 19 | 0.0295256 |
| SVIL | supervillin | 0.0294653 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0294156 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0292889 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0289176 |
| FRMD5 | FERM domain containing 5 | 0.0287531 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0287449 |
| KLC1 | kinesin light chain 1 | 0.0286851 |
| MED13L | mediator complex subunit 13-like | 0.0286728 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.027877 |
| FHIT | fragile histidine triad | 0.027859 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0278482 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0277295 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.027702 |
| ITGB5 | integrin, beta 5 | 0.0274021 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0273961 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0272802 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0271109 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0269126 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266286 |
| CEP250 | centrosomal protein 250kDa | 0.0265371 |
| SMAD3 | SMAD family member 3 | 0.0263749 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0263634 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0261298 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0260536 |
| HMG20B | high mobility group 20B | 0.0260514 |
| NBAS | neuroblastoma amplified sequence | 0.0259538 |
| FAM219A | family with sequence similarity 219, member A | 0.0256561 |
| NGLY1 | N-glycanase 1 | 0.0255758 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0255245 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254865 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253616 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0251259 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0251248 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0250533 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0249712 |
| ARRDC3 | arrestin domain containing 3 | 0.0248674 |
| RASAL2 | RAS protein activator like 2 | 0.0247005 |
| CTBP2 | C-terminal binding protein 2 | 0.0246899 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.024433 |
| MKI67 | marker of proliferation Ki-67 | 0.0244183 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0241344 |
| ANGPTL4 | angiopoietin-like 4 | 0.0238591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.196949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128524 |
| LSAMP | limbic system-associated membrane protein | -0.104346 |
| CCND1 | cyclin D1 | -0.0839246 |
| NLGN1 | neuroligin 1 | -0.0676795 |
| VDAC1 | voltage-dependent anion channel 1 | -0.061392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0548515 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0533827 |
| ACTG1 | actin gamma 1 | -0.0489506 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0489303 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0464863 |
| RPLP1 | ribosomal protein, large, P1 | -0.0398548 |
| FTL | ferritin, light polypeptide | -0.0372244 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0369705 |
| RPS24 | ribosomal protein S24 | -0.0366457 |
| TUBB | tubulin, beta class I | -0.0364757 |
| TKT | transketolase | -0.0363408 |
| GOLGA4 | golgin A4 | -0.0352919 |
| PMEL | premelanosome protein | -0.0351315 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0343244 |
| RRBP1 | ribosome binding protein 1 | -0.0331292 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.03244 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0322522 |
| CBX3 | chromobox homolog 3 | -0.0322024 |
| POTEF | POTE ankyrin domain family, member F | -0.0321875 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0315914 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0307335 |
| CANX | calnexin | -0.0299058 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0293377 |
| APOD | apolipoprotein D | -0.0287441 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0286456 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0283599 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0279768 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0278691 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0270202 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270071 |
| RPS6 | ribosomal protein S6 | -0.0267808 |
| H3-3B | H3.3 histone B | -0.026189 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0261802 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261526 |
| DEK | DEK proto-oncogene | -0.0259767 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0258566 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0255868 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0251457 |
| FUS | FUS RNA binding protein | -0.0245271 |
| ACLY | ATP citrate lyase | -0.0243808 |
| NPR2 | natriuretic peptide receptor 2 | -0.0242036 |
| RPL34 | ribosomal protein L34 | -0.0241814 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.02373 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0237244 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0236171 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0234196 |
| NKTR | natural killer cell triggering receptor | -0.0234182 |
| RPL14 | ribosomal protein L14 | -0.0232425 |
| TMSB10 | thymosin beta 10 | -0.022946 |
| TMEM263 | transmembrane protein 263 | -0.0228345 |
| RPS5 | ribosomal protein S5 | -0.0227297 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0222836 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0222323 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0219055 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0218683 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0217688 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0217349 |
| NRN1 | neuritin 1 | -0.0214006 |
| SGO2 | shugoshin 2 | -0.0213181 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0211654 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0211213 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0209221 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0208614 |
| RPS23 | ribosomal protein S23 | -0.0207803 |
| RPL38 | ribosomal protein L38 | -0.0206683 |
| PTMA | prothymosin, alpha | -0.0206125 |
| RPL28 | ribosomal protein L28 | -0.0205732 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0205498 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0204707 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0203698 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.020347 |
| SEPTIN7 | septin 7 | -0.0203197 |
| FMN1 | formin 1 | -0.0202595 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0201385 |
| SNX14 | sorting nexin 14 | -0.0196179 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0195832 |
| EMP1 | epithelial membrane protein 1 | -0.0195511 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0195491 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0195418 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0194777 |
| MITF | microphthalmia-associated transcription factor | -0.0194515 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0193335 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0193326 |
| COMMD10 | COMM domain containing 10 | -0.0192937 |
| GOLM2 | golgi membrane protein 2 | -0.0192117 |
| RPL32 | ribosomal protein L32 | -0.0189661 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0189492 |
| RPL27A | ribosomal protein L27a | -0.0188106 |
| HMGB1 | high mobility group box 1 | -0.0187001 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0185553 |
| PRAME | preferentially expressed antigen in melanoma | -0.0185034 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0183564 |
| IER3 | immediate early response 3 | -0.0179456 |
