Chloroquine Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. (Chemical Entities of Biological Interest Ontology, CHEBI_3638)
External Link http://www.hmdb.ca/metabolites/HMDB14746
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Genes

9 interacting proteins for the Chloroquine metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
GSTA2 glutathione S-transferase alpha 2
TLR9 toll-like receptor 9
TNF tumor necrosis factor