Cholangitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A bile duct disease that is an inflammation of the bile duct. (Human Disease Ontology, DOID_9446)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D002761
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Genes

111 genes/proteins associated with the disease Cholangitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.88009
CA2 carbonic anhydrase II 2.88009
TNF tumor necrosis factor 1.754
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.59755
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.59451
VCAM1 vascular cell adhesion molecule 1 1.58279
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.58184
ICAM1 intercellular adhesion molecule 1 1.56899
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.56607
GCLC glutamate-cysteine ligase, catalytic subunit 1.56435
GCLM glutamate-cysteine ligase, modifier subunit 1.54451
IL1B interleukin 1, beta 1.50953
CXCL2 chemokine (C-X-C motif) ligand 2 1.50146
IL6 interleukin 6 1.47838
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.45936
NQO1 NAD(P)H dehydrogenase, quinone 1 1.42616
TGFB1 transforming growth factor, beta 1 1.42047
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.41911
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.41559
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.40787
VEGFA vascular endothelial growth factor A 1.39282
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.38469
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.36447
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.36247
CXCL8 chemokine (C-X-C motif) ligand 8 1.32518
FAS Fas cell surface death receptor 1.32162
IL1A interleukin 1, alpha 1.31867
DDIT3 DNA-damage-inducible transcript 3 1.29781
GSTA2 glutathione S-transferase alpha 2 1.29564
CAT catalase 1.27286
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.2707
ATF4 activating transcription factor 4 1.26917
PARP1 poly (ADP-ribose) polymerase 1 1.2639
BAX BCL2-associated X protein 1.26359
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.25338
PKLR pyruvate kinase, liver and RBC 1.2475
TIMP1 TIMP metallopeptidase inhibitor 1 1.24591
IL10 interleukin 10 1.23296
GSTP1 glutathione S-transferase pi 1 1.23233
FOS FBJ murine osteosarcoma viral oncogene homolog 1.22112
GSTT1 glutathione S-transferase theta 1 1.2208
RB1 retinoblastoma 1 1.21206
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.20784
GSS glutathione synthetase 1.2059
PCNA proliferating cell nuclear antigen 1.19966
TAGLN transgelin 1.19639
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.19014
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.18359
EDN1 endothelin 1 1.17959
CXCL10 chemokine (C-X-C motif) ligand 10 1.16833
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.16799
TP53 tumor protein p53 1.16269
HMOX1 heme oxygenase 1 1.1617
EGF epidermal growth factor 1.15831
JUN jun proto-oncogene 1.15526
CCND1 cyclin D1 1.15089
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.15055
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.15022
NOS2 nitric oxide synthase 2, inducible 1.14919
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.1485
ACSL1 acyl-CoA synthetase long-chain family member 1 1.1485
SOD2 superoxide dismutase 2, mitochondrial 1.14644
GAMT guanidinoacetate N-methyltransferase 1.14507
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.14404
NAP1L1 nucleosome assembly protein 1-like 1 1.14234
GSR glutathione reductase 1.14098
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.13793
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.13177
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.12805
NUPR1 nuclear protein, transcriptional regulator, 1 1.12599
AKR1C2 aldo-keto reductase family 1, member C2 1.12082
IFNG interferon, gamma 1.12014
IGFBP1 insulin-like growth factor binding protein 1 1.11741
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.11571
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.1122
BCL2L1 BCL2-like 1 1.11081
BCL2 B-cell CLL/lymphoma 2 1.10317
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.10069
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.09857
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.09822
CCL2 chemokine (C-C motif) ligand 2 1.09366
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.09047
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.08655
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.08655
MT2A metallothionein 2A 1.07983
LDLR low density lipoprotein receptor 1.0734
GSTM2 glutathione S-transferase mu 2 (muscle) 1.07022
ALB albumin 1.06808
MAPK3 mitogen-activated protein kinase 3 1.06333
PPARG peroxisome proliferator-activated receptor gamma 1.05936
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.05648
MAPK1 mitogen-activated protein kinase 1 1.05498
CD36 CD36 molecule (thrombospondin receptor) 1.05461
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.05461
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.05237
GDF15 growth differentiation factor 15 1.05237
CLU clusterin 1.04465
MCL1 myeloid cell leukemia 1 1.03901
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.03864
MPO myeloperoxidase 1.0353
SLC51B solute carrier family 51, beta subunit 1.0353
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.03419
HMGB1 high mobility group box 1 1.02783
PPARA peroxisome proliferator-activated receptor alpha 1.02559
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.02522
FASN fatty acid synthase 1.02225
HSPA1A heat shock 70kDa protein 1A 1.02114
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.01512
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.01212
S100A9 S100 calcium binding protein A9 1.01212
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.01137