Cholangitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A bile duct disease that is an inflammation of the bile duct. (Human Disease Ontology, DOID_9446)
External Link https://www.disgenet.org/browser/0/1/0/C0008311
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Genes

76 genes associated with the disease Cholangitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
AICDA activation-induced cytidine deaminase
ALB albumin
ATM ATM serine/threonine kinase
BCL3 B-cell CLL/lymphoma 3
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BECN1 beclin 1, autophagy related
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIITA class II, major histocompatibility complex, transactivator
CLDN1 claudin 1
COL1A1 collagen, type I, alpha 1
COPS5 COP9 signalosome subunit 5
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL2 chemokine (C-X-C motif) ligand 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
EBAG9 estrogen receptor binding site associated, antigen, 9
EGFR epidermal growth factor receptor
EGR1 early growth response 1
FUT2 fucosyltransferase 2 (secretor status included)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GGTLC1 gamma-glutamyltransferase light chain 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGB1 high mobility group box 1
IFNG interferon, gamma
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL2 interleukin 2
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL32 interleukin 32
IL7 interleukin 7
ITCH itchy E3 ubiquitin protein ligase
ITGB6 integrin, beta 6
KLF5 Kruppel-like factor 5 (intestinal)
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LMNA lamin A/C
LOC101060233 medium-wave-sensitive opsin 1
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
NFE2L2 nuclear factor, erythroid 2-like 2
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2
ORM2 orosomucoid 2
PDZD2 PDZ domain containing 2
PLA2G10 phospholipase A2, group X
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2D phospholipase A2, group IID
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFXANK regulatory factor X-associated ankyrin-containing protein
RFXAP regulatory factor X-associated protein
RRAS related RAS viral (r-ras) oncogene homolog
S100A6 S100 calcium binding protein A6
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOST sclerostin
TGFB2 transforming growth factor, beta 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
VIM vimentin
VWF von Willebrand factor
WDR35 WD repeat domain 35