Cholecystitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A cholangitis that is an inflammation of the gallbladder. (Human Disease Ontology, DOID_1949)
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Genes

279 genes co-occuring with the disease Cholecystitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CRP C-reactive protein, pentraxin-related 3.138
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.121
ALB albumin 2.723
F2 coagulation factor II (thrombin) 2.609
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 2.608
CCK cholecystokinin 2.583
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.476
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.372
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.371
F3 coagulation factor III (thromboplastin, tissue factor) 2.271
SST somatostatin 2.232
AFP alpha-fetoprotein 2.209
IL6 interleukin 6 2.188
INS insulin 2.172
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.064
KRT7 keratin 7, type II 2.048
GCG glucagon 2.033
TNF tumor necrosis factor 2.027
KRT20 keratin 20, type I 1.936
CD4 CD4 molecule 1.912
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.908
CCKAR cholecystokinin A receptor 1.903
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.888
TP53 tumor protein p53 1.886
ACE2 angiotensin I converting enzyme 2 1.881
CHGA chromogranin A 1.877
IL1B interleukin 1, beta 1.859
KRT19 keratin 19, type I 1.855
GLP1R glucagon-like peptide 1 receptor 1.84
PDPN podoplanin 1.837
SYP synaptophysin 1.827
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.792
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.778
ACE angiotensin I converting enzyme 1.769
CD8A CD8a molecule 1.769
IL10 interleukin 10 1.759
KRAS Kirsten rat sarcoma viral oncogene homolog 1.754
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.75
GAST gastrin 1.742
MUC6 mucin 6, oligomeric mucus/gel-forming 1.742
CD34 CD34 molecule 1.74
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.727
CDX2 caudal type homeobox 2 1.725
MUC1 mucin 1, cell surface associated 1.723
MME membrane metallo-endopeptidase 1.697
DPP4 dipeptidyl-peptidase 4 1.696
CXCL8 chemokine (C-X-C motif) ligand 8 1.69
HP haptoglobin 1.689
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.677
IFNG interferon, gamma 1.666
CP ceruloplasmin (ferroxidase) 1.656
CD68 CD68 molecule 1.645
MLN motilin 1.639
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.639
PNLIP pancreatic lipase 1.638
FGF19 fibroblast growth factor 19 1.635
ERBB2 erb-b2 receptor tyrosine kinase 2 1.625
NCAM1 neural cell adhesion molecule 1 1.618
GPBAR1 G protein-coupled bile acid receptor 1 1.614
SSBP2 single-stranded DNA binding protein 2 1.61
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.604
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.592
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.585
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.585
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.579
POMC proopiomelanocortin 1.572
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 1.572
MPO myeloperoxidase 1.566
CKB creatine kinase, brain 1.554
CKM creatine kinase, muscle 1.547
CKMT1B creatine kinase, mitochondrial 1B 1.547
IL1A interleukin 1, alpha 1.546
MUC2 mucin 2, oligomeric mucus/gel-forming 1.544
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.543
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.524
CD274 CD274 molecule 1.522
CSF3 colony stimulating factor 3 (granulocyte) 1.517
EGFR epidermal growth factor receptor 1.514
IL2 interleukin 2 1.51
SCT secretin 1.496
TGFB1 transforming growth factor, beta 1 1.484
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.47
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.469
GIP gastric inhibitory polypeptide 1.469
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.465
ALK anaplastic lymphoma receptor tyrosine kinase 1.459
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.458
LEP leptin 1.453
TLR4 toll-like receptor 4 1.448
SSTR5 somatostatin receptor 5 1.445
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.442
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.438
ZNF107 zinc finger protein 107 1.436
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.436
ALPG alkaline phosphatase, germ cell 1.434
IL4 interleukin 4 1.427
ALPI alkaline phosphatase, intestinal 1.409
PXDNL peroxidasin-like 1.409
PXDN peroxidasin 1.407
CD5 CD5 molecule 1.406
ESR1 estrogen receptor 1 1.397
GPC3 glypican 3 1.389
ENO2 enolase 2 (gamma, neuronal) 1.389
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.388
BCL2 B-cell CLL/lymphoma 2 1.384
VIP vasoactive intestinal peptide 1.381
IL17A interleukin 17A 1.38
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.38
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.37
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.366
ALPP alkaline phosphatase, placental 1.366
NPPB natriuretic peptide B 1.361
KNG1 kininogen 1 1.355
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.353
CDKN2A cyclin-dependent kinase inhibitor 2A 1.352
SSTR2 somatostatin receptor 2 1.351
ACTB actin, beta 1.351
ALPL alkaline phosphatase, liver/bone/kidney 1.35
REN renin 1.349
PRTN3 proteinase 3 1.349
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.347
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.341
AVP arginine vasopressin 1.34
SPINK1 serine peptidase inhibitor, Kazal type 1 1.337
IL5 interleukin 5 1.326
JUN jun proto-oncogene 1.322
SMAD4 SMAD family member 4 1.314
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.313
SSTR1 somatostatin receptor 1 1.305
PDCD1 programmed cell death 1 1.304
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.296
GGT1 gamma-glutamyltransferase 1 1.291
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.29
JAK2 Janus kinase 2 1.289
IGF1 insulin-like growth factor 1 (somatomedin C) 1.287
ACR acrosin 1.279
DNAL1 dynein, axonemal, light chain 1 1.278
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.278
APP-DT APP divergent transcript 1.277
CCL2 chemokine (C-C motif) ligand 2 1.277
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.273
MLH1 mutL homolog 1 1.272
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 1.27
PYY peptide YY 1.269
MB myoglobin 1.269
H2AC11 H2A clustered histone 11 1.245
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.241
APOB apolipoprotein B 1.24
CD19 CD19 molecule 1.231
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.229
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.226
KRT18 keratin 18, type I 1.221
ADIPOQ adiponectin, C1Q and collagen domain containing 1.221
SENP8 SUMO/sentrin specific peptidase family member 8 1.22
FGFR2 fibroblast growth factor receptor 2 1.217
LPAR1 lysophosphatidic acid receptor 1 1.215
PRSS1 protease, serine, 1 (trypsin 1) 1.21
S100A8 S100 calcium binding protein A8 1.21
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.209
TAC1 tachykinin, precursor 1 1.207
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.205
BCL6 B-cell CLL/lymphoma 6 1.205
FABP2 fatty acid binding protein 2, intestinal 1.204
THBD thrombomodulin 1.202
ANO1 anoctamin 1, calcium activated chloride channel 1.192
EGF epidermal growth factor 1.19
PGR progesterone receptor 1.189
MUC4 mucin 4, cell surface associated 1.187
PECAM1 platelet/endothelial cell adhesion molecule 1 1.186
H2AC16 H2A clustered histone 16 1.183
ARID1A AT rich interactive domain 1A (SWI-like) 1.178
SDC1 syndecan 1 1.175
FGFR4 fibroblast growth factor receptor 4 1.175
RET ret proto-oncogene 1.175
MMP9 matrix metallopeptidase 9 1.174
CD79A CD79a molecule, immunoglobulin-associated alpha 1.172
IFNB1 interferon, beta 1, fibroblast 1.171
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.169
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.168
KRT8 keratin 8, type II 1.167
PTH parathyroid hormone 1.167
FLT1 fms-related tyrosine kinase 1 1.166
KDR kinase insert domain receptor 1.162
CCND1 cyclin D1 1.159
GHRL ghrelin/obestatin prepropeptide 1.15
SI sucrase-isomaltase (alpha-glucosidase) 1.143
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.139
TLR2 toll-like receptor 2 1.137
CD52 CD52 molecule 1.134
MGAM maltase-glucoamylase 1.133
BCHE butyrylcholinesterase 1.131
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.128
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.127
SPTB spectrin, beta, erythrocytic 1.123
IL13 interleukin 13 1.119
PLG plasminogen 1.117
VIM vimentin 1.109
CCL28 chemokine (C-C motif) ligand 28 1.107
SPN sialophorin 1.104
EPO erythropoietin 1.103
IFNA1 interferon, alpha 1 1.101
LINC02983 long intergenic non-protein coding RNA 2983 1.1
C3 complement component 3 1.099
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.098
GGTLC3 gamma-glutamyltransferase light chain 3 1.097
CALB2 calbindin 2 1.097
PPY pancreatic polypeptide 1.097
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.096
PAX8 paired box 8 1.095
LTF lactotransferrin 1.095
VWF von Willebrand factor 1.094
PTPRC protein tyrosine phosphatase, receptor type, C 1.093
IL18 interleukin 18 1.089
ACTA1 actin, alpha 1, skeletal muscle 1.087
LCN2 lipocalin 2 1.086
NKX2-1 NK2 homeobox 1 1.082
FCGBP Fc fragment of IgG binding protein 1.082
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.081
ERBB3 erb-b2 receptor tyrosine kinase 3 1.078
PPARG peroxisome proliferator-activated receptor gamma 1.075
FGF10 fibroblast growth factor 10 1.075
FOXP3 forkhead box P3 1.072
TG thyroglobulin 1.069
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.068
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 1.067
TTR transthyretin 1.066
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.065
CTSF cathepsin F 1.065
ZNF397 zinc finger protein 397 1.064
DAPK1 death-associated protein kinase 1 1.063
MSH2 mutS homolog 2 1.061
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.061
ELANE elastase, neutrophil expressed 1.058
IL7 interleukin 7 1.056
FN1 fibronectin 1 1.055
FGF4 fibroblast growth factor 4 1.054
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.053
G6PD glucose-6-phosphate dehydrogenase 1.053
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.053
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1.051
HAMP hepcidin antimicrobial peptide 1.05
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.049
FGF5 fibroblast growth factor 5 1.044
TNNI3 troponin I type 3 (cardiac) 1.042
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.04
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.04
PPARA peroxisome proliferator-activated receptor alpha 1.038
FGF7 fibroblast growth factor 7 1.038
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.036
FHIT fragile histidine triad 1.034
UBAC1 UBA domain containing 1 1.034
GLP2R glucagon-like peptide 2 receptor 1.033
IFNA2 interferon, alpha 2 1.032
EPCAM epithelial cell adhesion molecule 1.03
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11 1.028
FGF22 fibroblast growth factor 22 1.028
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.028
CTSB cathepsin B 1.027
FGF6 fibroblast growth factor 6 1.026
FGF16 fibroblast growth factor 16 1.026
PCNA proliferating cell nuclear antigen 1.026
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.026
FIP1L1 factor interacting with PAPOLA and CPSF1 1.025
GUSB glucuronidase, beta 1.025
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.024
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.023
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.023
FGF20 fibroblast growth factor 20 1.023
FGF9 fibroblast growth factor 9 1.022
FGF17 fibroblast growth factor 17 1.021
FGF18 fibroblast growth factor 18 1.018
CCKBR cholecystokinin B receptor 1.016
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.013
FGF3 fibroblast growth factor 3 1.012
FBL fibrillarin 1.011
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.004
HMGB1 high mobility group box 1 1.003
FGF8 fibroblast growth factor 8 (androgen-induced) 1.003
APOA1 apolipoprotein A-I 1.002