Cholesteatoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

175 genes co-occuring with the disease Cholesteatoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
KRT13 keratin 13, type I 2.143
KRT16 keratin 16, type I 2.131
KRT10 keratin 10, type I 2.116
FGF7 fibroblast growth factor 7 2.105
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.075
IL1A interleukin 1, alpha 2.059
FAM227A family with sequence similarity 227, member A 2.011
TGFA transforming growth factor, alpha 1.999
IVL involucrin 1.91
FGF2 fibroblast growth factor 2 (basic) 1.809
IL1B interleukin 1, beta 1.796
MMP9 matrix metallopeptidase 9 1.793
TNF tumor necrosis factor 1.78
PCNA proliferating cell nuclear antigen 1.773
EGF epidermal growth factor 1.733
IL6 interleukin 6 1.689
KRT1 keratin 1, type II 1.671
KRT4 keratin 4, type II 1.666
TLR4 toll-like receptor 4 1.652
MMP2 matrix metallopeptidase 2 1.639
TLR2 toll-like receptor 2 1.639
HEPHL1 hephaestin-like 1 1.629
KRT14 keratin 14, type I 1.624
RGS22 regulator of G-protein signaling 22 1.609
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.602
LGALS8 lectin, galactoside-binding, soluble, 8 1.595
FGFR2 fibroblast growth factor receptor 2 1.594
GJB2 gap junction protein, beta 2, 26kDa 1.591
FBXO11 F-box protein 11 1.59
FLG2 filaggrin family member 2 1.533
BPIFA3 BPI fold containing family A, member 3 1.528
CDH18 cadherin 18, type 2 1.515
BPIFA1 BPI fold containing family A, member 1 1.513
KRT5 keratin 5, type II 1.509
SPRR1B small proline-rich protein 1B 1.509
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.494
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.489
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 1.483
EGFR epidermal growth factor receptor 1.468
PNRC1 proline-rich nuclear receptor coactivator 1 1.463
CDH19 cadherin 19, type 2 1.46
COCH cochlin 1.456
SYP synaptophysin 1.452
KRT18 keratin 18, type I 1.451
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45
DEFB4A defensin, beta 4A 1.443
FLG filaggrin 1.443
CRYBG1 crystallin beta-gamma domain containing 1 1.432
CXCL8 chemokine (C-X-C motif) ligand 8 1.428
TGFB1 transforming growth factor, beta 1 1.427
TP53 tumor protein p53 1.426
PTHLH parathyroid hormone-like hormone 1.42
DCHS1 dachsous cadherin-related 1 1.398
KRT7 keratin 7, type II 1.393
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.388
ACP5 acid phosphatase 5, tartrate resistant 1.386
FN1 fibronectin 1 1.371
CCND1 cyclin D1 1.359
DENND2C DENN/MADD domain containing 2C 1.355
LY75-CD302 LY75-CD302 readthrough 1.353
PTEN phosphatase and tensin homolog 1.34
CYLD cylindromatosis (turban tumor syndrome) 1.329
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.329
CTSK cathepsin K 1.324
TIMP4 TIMP metallopeptidase inhibitor 4 1.322
A2ML1 alpha-2-macroglobulin-like 1 1.32
EGFL8 EGF-like-domain, multiple 8 1.32
EYA4 EYA transcriptional coactivator and phosphatase 4 1.315
S100A7 S100 calcium binding protein A7 1.298
PXDNL peroxidasin-like 1.29
PXDN peroxidasin 1.289
TIMP1 TIMP metallopeptidase inhibitor 1 1.288
KRT19 keratin 19, type I 1.283
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.281
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.281
FGF8 fibroblast growth factor 8 (androgen-induced) 1.273
LGALS7 lectin, galactoside-binding, soluble, 7 1.268
LGALS7B lectin, galactoside-binding, soluble, 7B 1.268
CCIN calicin 1.267
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.267
EREG epiregulin 1.267
CASP14 caspase 14, apoptosis-related cysteine peptidase 1.266
TBX10 T-box 10 1.254
MMP3 matrix metallopeptidase 3 1.249
ANKRD33B ankyrin repeat domain 33B 1.245
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.242
EFCAB6 EF-hand calcium binding domain 6 1.241
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.239
FGF3 fibroblast growth factor 3 1.235
FGF22 fibroblast growth factor 22 1.233
ICAM1 intercellular adhesion molecule 1 1.232
MMP8 matrix metallopeptidase 8 1.228
LY75 lymphocyte antigen 75 1.226
FGF18 fibroblast growth factor 18 1.223
FGF10 fibroblast growth factor 10 1.22
TREM2 triggering receptor expressed on myeloid cells 2 1.216
GJB6 gap junction protein, beta 6, 30kDa 1.214
FGF16 fibroblast growth factor 16 1.214
FGF6 fibroblast growth factor 6 1.213
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.211
FGF20 fibroblast growth factor 20 1.211
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 1.211
FGF17 fibroblast growth factor 17 1.209
FGF5 fibroblast growth factor 5 1.205
CLEC12B C-type lectin domain family 12, member B 1.196
FGF9 fibroblast growth factor 9 1.196
KRT8 keratin 8, type II 1.191
FGF4 fibroblast growth factor 4 1.19
S100A1 S100 calcium binding protein A1 1.185
S100A7A S100 calcium binding protein A7A 1.185
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.182
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.171
CDHR3 cadherin-related family member 3 1.168
MMP1 matrix metallopeptidase 1 1.168
AQP5 aquaporin 5 1.165
TGM3 transglutaminase 3 1.162
SPINK5 serine peptidase inhibitor, Kazal type 5 1.161
MYO7A myosin VIIA 1.156
NOD1 nucleotide-binding oligomerization domain containing 1 1.149
JUN jun proto-oncogene 1.145
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.144
IL10 interleukin 10 1.142
ATOH1 atonal homolog 1 (Drosophila) 1.142
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1.141
RARB retinoic acid receptor, beta 1.14
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.139
ANGPT2 angiopoietin 2 1.138
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.137
TREM1 triggering receptor expressed on myeloid cells 1 1.137
CFLAR CASP8 and FADD-like apoptosis regulator 1.134
FKBP4 FK506 binding protein 4, 59kDa 1.134
MMP13 matrix metallopeptidase 13 1.129
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.127
PECAM1 platelet/endothelial cell adhesion molecule 1 1.127
CD68 CD68 molecule 1.123
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.122
COL9A1 collagen, type IX, alpha 1 1.117
BMP4 bone morphogenetic protein 4 1.103
SUCO SUN domain containing ossification factor 1.102
SHOX short stature homeobox 1.097
CD1E CD1e molecule 1.096
LGALS3 lectin, galactoside-binding, soluble, 3 1.094
HBEGF heparin-binding EGF-like growth factor 1.091
RUBCN rubicon autophagy regulator 1.087
CD1A CD1a molecule 1.086
ACTB actin, beta 1.081
CD1B CD1b molecule 1.078
FUT2 fucosyltransferase 2 (secretor status included) 1.077
HMGA2 high mobility group AT-hook 2 1.076
NF2 neurofibromin 2 (merlin) 1.074
CDH23 cadherin-related 23 1.073
MYD88 myeloid differentiation primary response 88 1.073
ARID3A AT rich interactive domain 3A (BRIGHT-like) 1.069
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.067
NOD2 nucleotide-binding oligomerization domain containing 2 1.062
AREG amphiregulin 1.062
TLR3 toll-like receptor 3 1.058
OCM2 oncomodulin 2 1.055
BMP6 bone morphogenetic protein 6 1.053
S100A9 S100 calcium binding protein A9 1.05
MMP10 matrix metallopeptidase 10 1.048
TP63 tumor protein p63 1.047
CRP C-reactive protein, pentraxin-related 1.046
EYA1 EYA transcriptional coactivator and phosphatase 1 1.042
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.03
FOXB1 forkhead box B1 1.028
PLG plasminogen 1.025
ASMT acetylserotonin O-methyltransferase 1.025
BMP2 bone morphogenetic protein 2 1.02
PRRC2C proline-rich coiled-coil 2C 1.02
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.018
PLCG1 phospholipase C, gamma 1 1.01
DNAH5 dynein, axonemal, heavy chain 5 1.007
POU4F3 POU class 4 homeobox 3 1.005
AQP3 aquaporin 3 (Gill blood group) 1.004