Cholesterol metabolism with Bloch and Kandutsch Russell pathways Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP4718.html
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Genes

47 proteins participating in the Cholesterol metabolism with Bloch and Kandutsch Russell pathways pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAT2 acetyl-CoA acetyltransferase 2
ACOT2 acyl-CoA thioesterase 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
CH25H cholesterol 25-hydroxylase
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ELOVL2 ELOVL fatty acid elongase 2
ELOVL3 ELOVL fatty acid elongase 3
ELOVL4 ELOVL fatty acid elongase 4
ELOVL5 ELOVL fatty acid elongase 5
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GGPS1 geranylgeranyl diphosphate synthase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
LBR lamin B receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
MYLIP myosin regulatory light chain interacting protein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSDHL NAD(P) dependent steroid dehydrogenase-like
PMVK phosphomevalonate kinase
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOAT1 sterol O-acyltransferase 1
SOAT2 sterol O-acyltransferase 2
SQLE squalene epoxidase
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
TM7SF2 transmembrane 7 superfamily member 2