Cholesterol metabolism Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP5304.html
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Genes

72 proteins participating in the Cholesterol metabolism pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACAT2 acetyl-CoA acetyltransferase 2
ANGPTL3 angiopoietin-like 3
ANGPTL8 angiopoietin like 8
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
CD36 CD36 molecule (thrombospondin receptor)
CETP cholesteryl ester transfer protein, plasma
CIDEB cell death-inducing DFFA-like effector b
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FABP2 fatty acid binding protein 2, intestinal
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
LBR lamin B receptor
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPC lipase, hepatic
LIPG lipase, endothelial
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MSMO1 methylsterol monooxygenase 1
MTTP microsomal triglyceride transfer protein
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
MYLIP myosin regulatory light chain interacting protein
NPC1 Niemann-Pick disease, type C1
NPC1L1 NPC1-like 1
NPC2 Niemann-Pick disease, type C2
NSDHL NAD(P) dependent steroid dehydrogenase-like
OSBPL5 oxysterol binding protein-like 5
PCSK9 proprotein convertase subtilisin/kexin type 9
PLTP phospholipid transfer protein
PMVK phosphomevalonate kinase
SAR1B secretion associated, Ras related GTPase 1B
SC5D sterol-C5-desaturase
SCARB1 scavenger receptor class B, member 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SOAT1 sterol O-acyltransferase 1
SORT1 sortilin 1
SQLE squalene epoxidase
STAR steroidogenic acute regulatory protein
STARD3 StAR-related lipid transfer (START) domain containing 3
TM7SF2 transmembrane 7 superfamily member 2
TSPO translocator protein (18kDa)
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VDAC1 voltage-dependent anion channel 1