Chondrosarcoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)|A malignant mesenchymal tumor arising from cartilage-forming tissues involving the bones. It affects middle-aged to elderly adults, and the pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion. (Experimental Factor Ontology, EFO_0000333)
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Genes

742 genes co-occuring with the disease Chondrosarcoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 3.173
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3.062
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3.013
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.941
EXT1 exostosin glycosyltransferase 1 2.922
EXT2 exostosin glycosyltransferase 2 2.911
CD99 CD99 molecule 2.857
CLSTN2 calsyntenin 2 2.843
CD99L2 CD99 molecule-like 2 2.776
NCOA2 nuclear receptor coactivator 2 2.635
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.579
TP53 tumor protein p53 2.565
ACAN aggrecan 2.535
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 2.513
COL2A1 collagen, type II, alpha 1 2.504
SOX9 SRY (sex determining region Y)-box 9 2.444
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.4
IHH indian hedgehog 2.385
SSX2 synovial sarcoma, X breakpoint 2 2.367
MYOG myogenin (myogenic factor 4) 2.355
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.339
CD34 CD34 molecule 2.323
MMP13 matrix metallopeptidase 13 2.284
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.283
CDKN2A cyclin-dependent kinase inhibitor 2A 2.282
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.276
FUS FUS RNA binding protein 2.275
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.268
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.265
CDK4 cyclin-dependent kinase 4 2.218
BCL2 B-cell CLL/lymphoma 2 2.216
PTHLH parathyroid hormone-like hormone 2.197
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.185
MYOD1 myogenic differentiation 1 2.177
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.176
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.174
IRF2BP2 interferon regulatory factor 2 binding protein 2 2.172
CCNB3 cyclin B3 2.163
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.157
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.153
CSAG1 chondrosarcoma associated gene 1 2.152
SYP synaptophysin 2.152
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.142
RUNX2 runt-related transcription factor 2 2.132
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.125
ZNF444 zinc finger protein 444 2.12
SATB2 SATB homeobox 2 2.108
SSX1 synovial sarcoma, X breakpoint 1 2.103
PAX3 paired box 3 2.092
ENO2 enolase 2 (gamma, neuronal) 2.09
NKX2-2 NK2 homeobox 2 2.077
EGFR epidermal growth factor receptor 2.077
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.067
CD274 CD274 molecule 2.06
FGF2 fibroblast growth factor 2 (basic) 2.059
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 2.056
PTH1R parathyroid hormone 1 receptor 2.053
TCF12 transcription factor 12 2.044
TGFB1 transforming growth factor, beta 1 2.042
GLI1 GLI family zinc finger 1 2.038
PTCH1 patched 1 2.011
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 2.01
KRT7 keratin 7, type II 2.005
CDX1 caudal type homeobox 1 1.998
CALD1 caldesmon 1 1.997
MMP2 matrix metallopeptidase 2 1.992
COL10A1 collagen, type X, alpha 1 1.992
ERBB2 erb-b2 receptor tyrosine kinase 2 1.989
WT1 Wilms tumor 1 1.98
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.978
CCN2 cellular communication network factor 2 1.972
PTEN phosphatase and tensin homolog 1.972
CCND1 cyclin D1 1.969
CCN6 cellular communication network factor 6 1.958
MMP9 matrix metallopeptidase 9 1.955
CNMD chondromodulin 1.948
SOX10 SRY (sex determining region Y)-box 10 1.94
PECAM1 platelet/endothelial cell adhesion molecule 1 1.937
H3-3B H3.3 histone B 1.937
IGF1R insulin-like growth factor 1 receptor 1.937
MMP1 matrix metallopeptidase 1 1.934
CCN3 cellular communication network factor 3 1.926
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.91
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.909
FH fumarate hydratase 1.907
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.901
H3-3A H3.3 histone A 1.887
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.884
NF1 neurofibromin 1 1.884
NAPRT nicotinate phosphoribosyltransferase 1.882
DUX4 double homeobox 4 1.879
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.879
CD44 CD44 molecule (Indian blood group) 1.878
ETV4 ets variant 4 1.877
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.876
TERT telomerase reverse transcriptase 1.872
TET2 tet methylcytosine dioxygenase 2 1.87
FGFR3 fibroblast growth factor receptor 3 1.869
MMP3 matrix metallopeptidase 3 1.865
ACTB actin, beta 1.861
D2HGDH D-2-hydroxyglutarate dehydrogenase 1.86
GLI2 GLI family zinc finger 2 1.855
PXDN peroxidasin 1.854
ETV1 ets variant 1 1.853
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.852
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.849
PXDNL peroxidasin-like 1.848
KDR kinase insert domain receptor 1.846
BCL2L1 BCL2-like 1 1.844
NCAM1 neural cell adhesion molecule 1 1.841
USP6 ubiquitin specific peptidase 6 1.839
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.837
CCN4 cellular communication network factor 4 1.828
PARP1 poly (ADP-ribose) polymerase 1 1.828
VGLL2 vestigial-like family member 2 1.827
TFE3 transcription factor binding to IGHM enhancer 3 1.814
CD68 CD68 molecule 1.814
FN1 fibronectin 1 1.813
FGF13 fibroblast growth factor 13 1.806
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.802
ALK anaplastic lymphoma receptor tyrosine kinase 1.801
FOXO1 forkhead box O1 1.797
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.797
KRAS Kirsten rat sarcoma viral oncogene homolog 1.792
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 1.786
CXCR4 chemokine (C-X-C motif) receptor 4 1.785
BMP2 bone morphogenetic protein 2 1.781
CREB3L2 cAMP responsive element binding protein 3-like 2 1.776
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.774
KRT5 keratin 5, type II 1.772
PAX7 paired box 7 1.767
SS18 synovial sarcoma translocation, chromosome 18 1.766
CCN1 cellular communication network factor 1 1.76
SHH sonic hedgehog 1.755
GFAP glial fibrillary acidic protein 1.753
EGF epidermal growth factor 1.751
EXTL1 exostosin-like glycosyltransferase 1 1.744
FGF18 fibroblast growth factor 18 1.737
FGFR1 fibroblast growth factor receptor 1 1.737
JUN jun proto-oncogene 1.735
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.734
EPAS1 endothelial PAS domain protein 1 1.734
CTAG1B cancer/testis antigen 1B 1.729
SMO smoothened, frizzled class receptor 1.725
FGF3 fibroblast growth factor 3 1.724
NUTM1 NUT midline carcinoma, family member 1 1.72
IGF1 insulin-like growth factor 1 (somatomedin C) 1.716
ESR1 estrogen receptor 1 1.715
HDAC9 histone deacetylase 9 1.714
BGLAP bone gamma-carboxyglutamate (gla) protein 1.714
CAMTA1 calmodulin binding transcription activator 1 1.713
FOS FBJ murine osteosarcoma viral oncogene homolog 1.709
FGF9 fibroblast growth factor 9 1.705
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.705
SSX2B synovial sarcoma, X breakpoint 2B 1.702
KRT20 keratin 20, type I 1.7
GNAS GNAS complex locus 1.697
H3C12 H3 clustered histone 12 1.696
FGF17 fibroblast growth factor 17 1.694
RET ret proto-oncogene 1.693
FAM20B family with sequence similarity 20, member B 1.692
FGF8 fibroblast growth factor 8 (androgen-induced) 1.69
MAPK3 mitogen-activated protein kinase 3 1.689
BAX BCL2-associated X protein 1.687
CREB1 cAMP responsive element binding protein 1 1.687
COMP cartilage oligomeric matrix protein 1.687
SOX6 SRY (sex determining region Y)-box 6 1.686
CD8A CD8a molecule 1.684
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.682
CSPG4 chondroitin sulfate proteoglycan 4 1.681
LDHA lactate dehydrogenase A 1.681
SPP1 secreted phosphoprotein 1 1.681
FGF4 fibroblast growth factor 4 1.68
SNAI1 snail family zinc finger 1 1.679
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.679
FGF6 fibroblast growth factor 6 1.677
FGF5 fibroblast growth factor 5 1.676
FGF10 fibroblast growth factor 10 1.676
CREB3L1 cAMP responsive element binding protein 3-like 1 1.673
KRT8 keratin 8, type II 1.672
COL1A1 collagen, type I, alpha 1 1.672
IL1B interleukin 1, beta 1.671
FGF20 fibroblast growth factor 20 1.669
FGF22 fibroblast growth factor 22 1.669
FGF16 fibroblast growth factor 16 1.668
FGF7 fibroblast growth factor 7 1.663
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.662
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.658
ANO1 anoctamin 1, calcium activated chloride channel 1.653
MUC4 mucin 4, cell surface associated 1.648
BIRC5 baculoviral IAP repeat containing 5 1.647
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.646
POU5F1 POU class 5 homeobox 1 1.642
NAMPT nicotinamide phosphoribosyltransferase 1.641
MET MET proto-oncogene, receptor tyrosine kinase 1.639
BRCA1 breast cancer 1, early onset 1.638
ALB albumin 1.636
CXCL12 chemokine (C-X-C motif) ligand 12 1.636
IL6 interleukin 6 1.632
KRT19 keratin 19, type I 1.629
MME membrane metallo-endopeptidase 1.628
SOX2 SRY (sex determining region Y)-box 2 1.626
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.626
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.626
ATM ATM serine/threonine kinase 1.625
H3-5 H3.5 histone 1.625
TFG TRK-fused gene 1.623
PLAG1 pleiomorphic adenoma gene 1 1.622
NKX3-1 NK3 homeobox 1 1.622
CSAG3 CSAG family, member 3 1.618
HMGA2 high mobility group AT-hook 2 1.618
SOX5 SRY (sex determining region Y)-box 5 1.614
IBSP integrin-binding sialoprotein 1.614
FLT4 fms-related tyrosine kinase 4 1.612
PTPRC protein tyrosine phosphatase, receptor type, C 1.61
VEGFC vascular endothelial growth factor C 1.61
H3C13 H3 clustered histone 13 1.61
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.607
TBXT T-box transcription factor T 1.605
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.603
H3-4 H3.4 histone, cluster member 1.603
TNF tumor necrosis factor 1.603
CCN5 cellular communication network factor 5 1.602
PRAME preferentially expressed antigen in melanoma 1.601
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.593
ETV6 ets variant 6 1.593
FLT1 fms-related tyrosine kinase 1 1.59
WWTR1 WW domain containing transcription regulator 1 1.587
SSX4 synovial sarcoma, X breakpoint 4 1.575
SP7 Sp7 transcription factor 1.574
PAX8 paired box 8 1.571
GLI3 GLI family zinc finger 3 1.57
SSX4B synovial sarcoma, X breakpoint 4B 1.563
PGR progesterone receptor 1.558
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.555
SUFU suppressor of fused homolog (Drosophila) 1.553
GLS glutaminase 1.553
ARID1A AT rich interactive domain 1A (SWI-like) 1.552
ANXA5 annexin A5 1.551
BMP7 bone morphogenetic protein 7 1.55
AURKA aurora kinase A 1.547
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.547
FGFR2 fibroblast growth factor receptor 2 1.546
CTSK cathepsin K 1.54
IGF2 insulin-like growth factor 2 1.538
YEATS2 YEATS domain containing 2 1.537
PCNA proliferating cell nuclear antigen 1.536
ATF1 activating transcription factor 1 1.53
CD4 CD4 molecule 1.529
FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.523
EXTL2 exostosin-like glycosyltransferase 2 1.522
SNAI2 snail family zinc finger 2 1.519
CDK6 cyclin-dependent kinase 6 1.519
NOTCH1 notch 1 1.518
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.517
PDPN podoplanin 1.516
PROM1 prominin 1 1.515
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.513
RGS16 regulator of G-protein signaling 16 1.511
TET1 tet methylcytosine dioxygenase 1 1.509
TBX3 T-box 3 1.509
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.504
COL9A1 collagen, type IX, alpha 1 1.498
ZC3H7B zinc finger CCCH-type containing 7B 1.498
CSF1R colony stimulating factor 1 receptor 1.495
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.491
PDCD1 programmed cell death 1 1.49
MTAP methylthioadenosine phosphorylase 1.49
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.49
DICER1 dicer 1, ribonuclease type III 1.485
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.479
PLGLB1 plasminogen-like B1 1.476
CALB2 calbindin 2 1.476
RB1 retinoblastoma 1 1.475
GSK3B glycogen synthase kinase 3 beta 1.473
MGMT O-6-methylguanine-DNA methyltransferase 1.472
GATA3 GATA binding protein 3 1.472
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.472
GLS2 glutaminase 2 (liver, mitochondrial) 1.47
PDGFB platelet-derived growth factor beta polypeptide 1.464
MIA melanoma inhibitory activity 1.462
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.461
NANOG Nanog homeobox 1.461
MCL1 myeloid cell leukemia 1 1.461
BGN biglycan 1.458
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.457
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.456
ZEB1 zinc finger E-box binding homeobox 1 1.45
HRAS Harvey rat sarcoma viral oncogene homolog 1.449
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.449
PTH parathyroid hormone 1.449
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.449
CXCL8 chemokine (C-X-C motif) ligand 8 1.448
INS insulin 1.441
KDM4A lysine (K)-specific demethylase 4A 1.441
SIRT1 sirtuin 1 1.438
BMP4 bone morphogenetic protein 4 1.436
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.432
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.432
BRD4 bromodomain containing 4 1.432
CD163 CD163 molecule 1.429
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.427
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.425
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.425
TIMP1 TIMP metallopeptidase inhibitor 1 1.422
BRCA2 breast cancer 2, early onset 1.422
KDM1A lysine (K)-specific demethylase 1A 1.421
CHGA chromogranin A 1.42
FGF1 fibroblast growth factor 1 (acidic) 1.419
FLT3 fms-related tyrosine kinase 3 1.416
PBRM1 polybromo 1 1.415
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.415
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.415
PBX1 pre-B-cell leukemia homeobox 1 1.413
HAS2 hyaluronan synthase 2 1.411
EXTL3 exostosin-like glycosyltransferase 3 1.411
HSPG2 heparan sulfate proteoglycan 2 1.408
CCL5 chemokine (C-C motif) ligand 5 1.407
KDM4C lysine (K)-specific demethylase 4C 1.407
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.405
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.405
TGFB3 transforming growth factor, beta 3 1.405
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.404
NF2 neurofibromin 2 (merlin) 1.403
DCN decorin 1.4
TFCP2 transcription factor CP2 1.398
MMP7 matrix metallopeptidase 7 1.398
INSM1 insulinoma-associated 1 1.397
SMAD3 SMAD family member 3 1.395
NCOA1 nuclear receptor coactivator 1 1.394
CYCS cytochrome c, somatic 1.393
BECN1 beclin 1, autophagy related 1.392
FRS2 fibroblast growth factor receptor substrate 2 1.391
PPARG peroxisome proliferator-activated receptor gamma 1.391
CCK cholecystokinin 1.388
PTK2 protein tyrosine kinase 2 1.387
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.386
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.386
MAP2K1 mitogen-activated protein kinase kinase 1 1.385
CD24 CD24 molecule 1.385
PKM pyruvate kinase, muscle 1.382
SETD2 SET domain containing 2 1.381
HDAC4 histone deacetylase 4 1.38
TIMP2 TIMP metallopeptidase inhibitor 2 1.379
YAP1 Yes-associated protein 1 1.377
MB myoglobin 1.376
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.376
CHEK2 checkpoint kinase 2 1.374
AFP alpha-fetoprotein 1.368
IFNG interferon, gamma 1.366
CSF1 colony stimulating factor 1 (macrophage) 1.365
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.365
MCM6 minichromosome maintenance complex component 6 1.365
PLAU plasminogen activator, urokinase 1.365
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.363
MAGEA4 melanoma antigen family A4 1.361
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.36
CDK2 cyclin-dependent kinase 2 1.358
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.357
ATG12 autophagy related 12 1.355
POSTN periostin, osteoblast specific factor 1.355
TP63 tumor protein p63 1.353
NKX3-2 NK3 homeobox 2 1.349
OSM oncostatin M 1.347
EPYC epiphycan 1.346
PDCD1LG2 programmed cell death 1 ligand 2 1.338
SALL4 spalt-like transcription factor 4 1.336
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.331
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.33
RHOA ras homolog family member A 1.329
RUNX3 runt-related transcription factor 3 1.329
WIF1 WNT inhibitory factor 1 1.327
ZC3H7A zinc finger CCCH-type containing 7A 1.327
FGF23 fibroblast growth factor 23 1.327
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.325
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.314
WNT3A wingless-type MMTV integration site family, member 3A 1.314
HDAC6 histone deacetylase 6 1.314
VTN vitronectin 1.313
ENG endoglin 1.312
TCHP trichoplein, keratin filament binding 1.312
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 1.31
CCL2 chemokine (C-C motif) ligand 2 1.31
SOX4 SRY (sex determining region Y)-box 4 1.309
IGFBP3 insulin-like growth factor binding protein 3 1.309
E2F1 E2F transcription factor 1 1.309
HNF4A hepatocyte nuclear factor 4, alpha 1.306
PHGDH phosphoglycerate dehydrogenase 1.304
EGLN1 egl-9 family hypoxia-inducible factor 1 1.303
STAT1 signal transducer and activator of transcription 1, 91kDa 1.301
CHAD chondroadherin 1.301
EZR ezrin 1.301
TGFB2 transforming growth factor, beta 2 1.3
SMAD4 SMAD family member 4 1.299
IL2 interleukin 2 1.297
ACP5 acid phosphatase 5, tartrate resistant 1.295
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.294
KRT18 keratin 18, type I 1.293
CDX2 caudal type homeobox 2 1.293
FLII flightless I homolog (Drosophila) 1.291
TIMP3 TIMP metallopeptidase inhibitor 3 1.289
HEATR3 HEAT repeat containing 3 1.287
SRY sex determining region Y 1.287
KLF17 Kruppel-like factor 17 1.286
KDM4B lysine (K)-specific demethylase 4B 1.281
EP300 E1A binding protein p300 1.28
B3GAT1 beta-1,3-glucuronyltransferase 1 1.279
IFT88 intraflagellar transport 88 1.278
FMOD fibromodulin 1.274
PDCD5 programmed cell death 5 1.274
AR androgen receptor 1.272
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.272
IL1A interleukin 1, alpha 1.269
MLH1 mutL homolog 1 1.268
ACVR2A activin A receptor, type IIA 1.268
EPHA2 EPH receptor A2 1.266
PBX3 pre-B-cell leukemia homeobox 3 1.265
SMAD2 SMAD family member 2 1.264
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.264
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.263
MITF microphthalmia-associated transcription factor 1.263
STK11 serine/threonine kinase 11 1.262
SULF1 sulfatase 1 1.261
CSAG2 CSAG family, member 2 1.261
THY1 Thy-1 cell surface antigen 1.259
MED12 mediator complex subunit 12 1.259
ADHFE1 alcohol dehydrogenase, iron containing, 1 1.257
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.257
DNTT DNA nucleotidylexotransferase 1.255
NUTM2A NUT family member 2A 1.255
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.255
GPC3 glypican 3 1.253
POTEF POTE ankyrin domain family, member F 1.253
GAGE13 G antigen 13 1.252
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.252
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.25
CTAG2 cancer/testis antigen 2 1.25
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.249
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.249
CCNB1 cyclin B1 1.249
FGFR4 fibroblast growth factor receptor 4 1.249
IL11 interleukin 11 1.249
STAG2 stromal antigen 2 1.247
WRN Werner syndrome, RecQ helicase-like 1.246
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.245
CCNL2 cyclin L2 1.243
CHEK1 checkpoint kinase 1 1.243
SOST sclerostin 1.242
KLF4 Kruppel-like factor 4 (gut) 1.241
FRZB frizzled-related protein 1.241
LOX lysyl oxidase 1.241
TWIST1 twist family bHLH transcription factor 1 1.24
BANF1 barrier to autointegration factor 1 1.239
CRP C-reactive protein, pentraxin-related 1.236
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.232
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.232
HDAC1 histone deacetylase 1 1.231
OSR2 odd-skipped related transciption factor 2 1.229
ILK integrin-linked kinase 1.228
TRPS1 trichorhinophalangeal syndrome I 1.228
ALPL alkaline phosphatase, liver/bone/kidney 1.228
MAML3 mastermind-like 3 (Drosophila) 1.228
ACLY ATP citrate lyase 1.227
WNT1 wingless-type MMTV integration site family, member 1 1.227
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.227
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.225
PRKCA protein kinase C, alpha 1.225
ETV5 ets variant 5 1.225
KAT6A K(lysine) acetyltransferase 6A 1.224
CDK1 cyclin-dependent kinase 1 1.223
COL11A1 collagen, type XI, alpha 1 1.222
HAPLN1 hyaluronan and proteoglycan link protein 1 1.222
TSC2 tuberous sclerosis 2 1.221
AURKB aurora kinase B 1.22
MMUT methylmalonyl-CoA mutase 1.22
RECQL4 RecQ protein-like 4 1.219
ZNF384 zinc finger protein 384 1.217
PTCH2 patched 2 1.216
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.216
CA9 carbonic anhydrase IX 1.215
COL18A1 collagen, type XVIII, alpha 1 1.214
VIM vimentin 1.213
CTSS cathepsin S 1.211
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.211
GDF5 growth differentiation factor 5 1.21
H2BC21 H2B clustered histone 21 1.209
CDC42 cell division cycle 42 1.208
NGFR nerve growth factor receptor 1.208
JAK2 Janus kinase 2 1.208
LEF1 lymphoid enhancer-binding factor 1 1.207
RARA retinoic acid receptor, alpha 1.198
HAVCR2 hepatitis A virus cellular receptor 2 1.194
ICAM1 intercellular adhesion molecule 1 1.192
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.19
PLK1 polo-like kinase 1 1.189
HOXA9 homeobox A9 1.187
RAD51 RAD51 recombinase 1.186
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.184
LAG3 lymphocyte-activation gene 3 1.184
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.182
NID1 nidogen 1 1.182
NKX2-1 NK2 homeobox 1 1.182
FOXP3 forkhead box P3 1.18
AGO2 argonaute RISC catalytic component 2 1.179
LRP6 low density lipoprotein receptor-related protein 6 1.178
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.177
NAPSA napsin A aspartic peptidase 1.177
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.176
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 1.175
SDC1 syndecan 1 1.173
BMP6 bone morphogenetic protein 6 1.173
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.171
ZNF687 zinc finger protein 687 1.171
ARID1B AT rich interactive domain 1B (SWI1-like) 1.17
KDM6B lysine (K)-specific demethylase 6B 1.17
IDO1 indoleamine 2,3-dioxygenase 1 1.17
KDM6A lysine (K)-specific demethylase 6A 1.168
NGF nerve growth factor (beta polypeptide) 1.168
NES nestin 1.168
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.168
MAPK8 mitogen-activated protein kinase 8 1.168
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.168
PRMT1 protein arginine methyltransferase 1 1.165
AHCY adenosylhomocysteinase 1.164
THBS1 thrombospondin 1 1.161
HSPA4 heat shock 70kDa protein 4 1.16
RETN resistin 1.16
DHH desert hedgehog 1.159
MEN1 multiple endocrine neoplasia I 1.158
RETNLB resistin like beta 1.156
GLUD2 glutamate dehydrogenase 2 1.156
HSPA8 heat shock 70kDa protein 8 1.155
CD276 CD276 molecule 1.154
FOXO3 forkhead box O3 1.154
SQSTM1 sequestosome 1 1.152
XYLT1 xylosyltransferase I 1.151
CCNA2 cyclin A2 1.15
CREBBP CREB binding protein 1.147
SP3 Sp3 transcription factor 1.146
H2AX H2A.X variant histone 1.144
H2AC20 H2A clustered histone 20 1.144
H2AC18 H2A clustered histone 18 1.143
ACKR3 atypical chemokine receptor 3 1.142
ADIPOQ adiponectin, C1Q and collagen domain containing 1.142
CD47 CD47 molecule 1.141
SIX1 SIX homeobox 1 1.138
H3C6 H3 clustered histone 6 1.138
ADAMTSL1 ADAMTS-like 1 1.136
WNT5A wingless-type MMTV integration site family, member 5A 1.134
JAZF1 JAZF zinc finger 1 1.134
ARNT aryl hydrocarbon receptor nuclear translocator 1.133
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 1.133
LUM lumican 1.132
LRP5 low density lipoprotein receptor-related protein 5 1.131
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 1.131
GID4 GID complex subunit 4 1.13
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.13
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1.129
MATN3 matrilin 3 1.129
IL10 interleukin 10 1.129
AREG amphiregulin 1.128
ITM2B integral membrane protein 2B 1.128
MAGEA1 melanoma antigen family A1 1.127
OLIG2 oligodendrocyte lineage transcription factor 2 1.127
PDGFA platelet-derived growth factor alpha polypeptide 1.126
KDM2A lysine (K)-specific demethylase 2A 1.126
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.125
AXL AXL receptor tyrosine kinase 1.124
MYB v-myb avian myeloblastosis viral oncogene homolog 1.122
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.12
TEK TEK tyrosine kinase, endothelial 1.119
CD1E CD1e molecule 1.119
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.118
MSH2 mutS homolog 2 1.117
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.116
P3H2 prolyl 3-hydroxylase 2 1.115
MAGEA3 melanoma antigen family A3 1.115
GTF2I general transcription factor IIi 1.114
VEGFD vascular endothelial growth factor D 1.113
MATN1 matrilin 1, cartilage matrix protein 1.111
MAPK1 mitogen-activated protein kinase 1 1.111
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.11
FASN fatty acid synthase 1.109
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.109
SUCO SUN domain containing ossification factor 1.108
ALCAM activated leukocyte cell adhesion molecule 1.106
COL1A2 collagen, type I, alpha 2 1.106
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.105
ERBB4 erb-b2 receptor tyrosine kinase 4 1.105
CEMIP cell migration inducing protein, hyaluronan binding 1.104
JAG1 jagged 1 1.104
ALX1 ALX homeobox 1 1.104
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.103
CD1B CD1b molecule 1.101
RAB6C RAB6C, member RAS oncogene family 1.101
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 1.101
DAAM2 dishevelled associated activator of morphogenesis 2 1.1
MSH6 mutS homolog 6 1.099
RUNX1 runt-related transcription factor 1 1.099
MEIS1 Meis homeobox 1 1.098
TYR tyrosinase 1.097
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.096
CD1A CD1a molecule 1.095
HHIP hedgehog interacting protein 1.094
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.094
DAXX death-domain associated protein 1.091
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.091
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.09
FASLG Fas ligand (TNF superfamily, member 6) 1.09
PLAUR plasminogen activator, urokinase receptor 1.09
SDHAF2 succinate dehydrogenase complex assembly factor 2 1.089
CCNA1 cyclin A1 1.087
FOXM1 forkhead box M1 1.084
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.084
GLUD1 glutamate dehydrogenase 1 1.084
ELN elastin 1.082
TBP TATA box binding protein 1.081
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.079
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.079
NOG noggin 1.078
PARVB parvin, beta 1.078
KLK3 kallikrein-related peptidase 3 1.077
EPCAM epithelial cell adhesion molecule 1.077
ATG5 autophagy related 5 1.076
MYH14 myosin, heavy chain 14, non-muscle 1.075
POMC proopiomelanocortin 1.075
TGFA transforming growth factor, alpha 1.073
RARG retinoic acid receptor, gamma 1.073
PRMT5 protein arginine methyltransferase 5 1.072
SULF2 sulfatase 2 1.07
SIRT5 sirtuin 5 1.069
TET3 tet methylcytosine dioxygenase 3 1.067
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.067
ACVR1 activin A receptor, type I 1.067
CAV1 caveolin 1, caveolae protein, 22kDa 1.066
ERBB3 erb-b2 receptor tyrosine kinase 3 1.065
BCL2L2 BCL2-like 2 1.065
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 1.065
S100A4 S100 calcium binding protein A4 1.065
FANCA Fanconi anemia, complementation group A 1.064
CTSB cathepsin B 1.063
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.062
ZNF264 zinc finger protein 264 1.061
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 1.061
ITGAV integrin, alpha V 1.06
LEP leptin 1.059
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.058
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.058
HK2 hexokinase 2 1.058
MRTFB myocardin related transcription factor B 1.058
PLG plasminogen 1.058
CD1C CD1c molecule 1.057
CCR7 chemokine (C-C motif) receptor 7 1.057
CSF3 colony stimulating factor 3 (granulocyte) 1.057
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.057
ARHGAP23 Rho GTPase activating protein 23 1.057
CD1D CD1d molecule 1.056
KMT2A lysine (K)-specific methyltransferase 2A 1.055
PGM1 phosphoglucomutase 1 1.054
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.054
COL27A1 collagen, type XXVII, alpha 1 1.054
HDAC2 histone deacetylase 2 1.053
ACSS2 acyl-CoA synthetase short-chain family member 2 1.052
NSD3 nuclear receptor binding SET domain protein 3 1.051
LGALS3 lectin, galactoside-binding, soluble, 3 1.051
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.05
VWF von Willebrand factor 1.05
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.049
CCND3 cyclin D3 1.049
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.049
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.048
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.048
GPR108 G protein-coupled receptor 108 1.047
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.045
FSCN1 fascin actin-bundling protein 1 1.045
COL11A2 collagen, type XI, alpha 2 1.045
PARVA parvin, alpha 1.043
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.043
EDN1 endothelin 1 1.042
LATS1 large tumor suppressor kinase 1 1.042
MUC1 mucin 1, cell surface associated 1.041
WEE1 WEE1 G2 checkpoint kinase 1.04
CHUK conserved helix-loop-helix ubiquitous kinase 1.04
PIP prolactin-induced protein 1.04
KAT2B K(lysine) acetyltransferase 2B 1.039
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.039
CD19 CD19 molecule 1.038
SMAD5 SMAD family member 5 1.038
CCND2 cyclin D2 1.038
ZEB2 zinc finger E-box binding homeobox 2 1.037
VGLL3 vestigial-like family member 3 1.036
VCAM1 vascular cell adhesion molecule 1 1.035
APAF1 apoptotic peptidase activating factor 1 1.034
ADGRG2 adhesion G protein-coupled receptor G2 1.034
MMP12 matrix metallopeptidase 12 1.033
KDM2B lysine (K)-specific demethylase 2B 1.032
FMNL1 formin-like 1 1.032
CCNE1 cyclin E1 1.031
RICTOR RPTOR independent companion of MTOR, complex 2 1.03
SRCIN1 SRC kinase signaling inhibitor 1 1.03
DOT1L DOT1-like histone H3K79 methyltransferase 1.029
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.029
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.028
AMACR alpha-methylacyl-CoA racemase 1.028
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.024
KMT2D lysine (K)-specific methyltransferase 2D 1.023
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.023
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.023
GLB1 galactosidase, beta 1 1.022
EGR1 early growth response 1 1.022
CD80 CD80 molecule 1.022
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.022
SLC16A4 solute carrier family 16, member 4 1.02
CD248 CD248 molecule, endosialin 1.02
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.019
NOTCH2 notch 2 1.019
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.018
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.018
PHF1 PHD finger protein 1 1.018
SIRPA signal-regulatory protein alpha 1.018
FOSL2 FOS-like antigen 2 1.017
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.017
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.016
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 1.016
TP53BP1 tumor protein p53 binding protein 1 1.016
SST somatostatin 1.015
DIAPH2 diaphanous-related formin 2 1.015
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.014
DDIT3 DNA-damage-inducible transcript 3 1.013
STAT5B signal transducer and activator of transcription 5B 1.013
COL6A3 collagen, type VI, alpha 3 1.013
BDNF brain-derived neurotrophic factor 1.011
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.01
DROSHA drosha, ribonuclease type III 1.008
VCAN versican 1.005
NFIB nuclear factor I/B 1.004
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.003
FMNL2 formin-like 2 1.001
FHOD1 formin homology 2 domain containing 1 1.0
NCOA3 nuclear receptor coactivator 3 1.0
CD79A CD79a molecule, immunoglobulin-associated alpha 1.0
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.0