Chordoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A notochordal cancer that derives_from cellular remnants of the notochord. (Human Disease Ontology, DOID_3302)
External Link https://www.disgenet.org/browser/0/1/0/C0008487
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Genes

126 genes associated with the disease Chordoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAN aggrecan
ADA adenosine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
AR androgen receptor
ARID4B AT rich interactive domain 4B (RBP1-like)
BCL6 B-cell CLL/lymphoma 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBR1 carbonyl reductase 1
CD24 CD24 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD38 CD38 molecule
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK2 checkpoint kinase 2
COL11A2 collagen, type XI, alpha 2
CSPG4 chondroitin sulfate proteoglycan 4
CTSK cathepsin K
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
DLK1 delta-like 1 homolog (Drosophila)
DVL1 dishevelled segment polarity protein 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FUBP1 far upstream element (FUSE) binding protein 1
GDE1 glycerophosphodiester phosphodiesterase 1
GFAP glial fibrillary acidic protein
GLI1 GLI family zinc finger 1
GSK3B glycogen synthase kinase 3 beta
HAVCR2 hepatitis A virus cellular receptor 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL2RB interleukin 2 receptor, beta
INSM1 insulinoma-associated 1
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LYST lysosomal trafficking regulator
MAPK1 mitogen-activated protein kinase 1
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MN1 meningioma (disrupted in balanced translocation) 1
MSH3 mutS homolog 3
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NGF nerve growth factor (beta polypeptide)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PARP1 poly (ADP-ribose) polymerase 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PSIP1 PC4 and SFRS1 interacting protein 1
PTEN phosphatase and tensin homolog
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPA protein phosphatase 2 phosphatase activator
RDX radixin
RNF144B ring finger protein 144B
SALL3 spalt-like transcription factor 3
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMAD3 SMAD family member 3
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMR3B submaxillary gland androgen regulated protein 3B
SNAI2 snail family zinc finger 2
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SRY sex determining region Y
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STATH statherin
T T, brachyury homolog (mouse)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX1 T-box 1
TCF3 transcription factor 3
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TRIM11 tripartite motif containing 11
TRIP13 thyroid hormone receptor interactor 13
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
YBX1 Y box binding protein 1