Chromosome Maintenance Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-73886
Similar Terms
Downloads & Tools

Genes

119 proteins participating in the Chromosome Maintenance pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ANKRD28 ankyrin repeat domain 28
ATRX alpha thalassemia/mental retardation syndrome X-linked
BLM Bloom syndrome, RecQ helicase-like
CCNA1 cyclin A1
CCNA2 cyclin A2
CDK2 cyclin-dependent kinase 2
CENPA centromere protein A
CENPC centromere protein C
CENPH centromere protein H
CENPI centromere protein I
CENPK centromere protein K
CENPL centromere protein L
CENPM centromere protein M
CENPN centromere protein N
CENPO centromere protein O
CENPP centromere protein P
CENPQ centromere protein Q
CENPS-CORT CENPS-CORT readthrough
CENPT centromere protein T
CENPU centromere protein U
CENPW centromere protein W
CENPX centromere protein X
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CTC1 CTS telomere maintenance complex component 1
DAXX death-domain associated protein
DKC1 dyskeratosis congenita 1, dyskerin
DNA2 DNA replication helicase/nuclease 2
DSCC1 DNA replication and sister chromatid cohesion 1
FEN1 flap structure-specific endonuclease 1
GAR1 GAR1 ribonucleoprotein
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-3A H3.3 histone A
H3-4 H3.4 histone, cluster member
H4C1 H4 clustered histone 1
HJURP Holliday junction recognition protein
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KNL1 kinetochore scaffold 1
LIG1 ligase I, DNA, ATP-dependent
MIS18A MIS18 kinetochore protein A
MIS18BP1 MIS18 binding protein 1
NHP2 NHP2 ribonucleoprotein
NOP10 NOP10 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
OIP5 Opa interacting protein 5
PCNA proliferating cell nuclear antigen
PIF1 PIF1 5'-to-3' DNA helicase
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POT1 protection of telomeres 1
PPP6C protein phosphatase 6, catalytic subunit
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RSF1 remodeling and spacing factor 1
RTEL1 regulator of telomere elongation helicase 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
STN1 STN1 subunit of CST complex
TEN1 TEN1 CST complex subunit
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
WRAP53 WD repeat containing, antisense to TP53
WRN Werner syndrome, RecQ helicase-like