Chronic Heart Failure Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cardiovascular (Genetic Association Database)
External Link https://www.disgenet.org/browser/0/1/0/C0264716
Similar Terms
Downloads & Tools

Genes

198 genes associated with the disease Chronic Heart Failure in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADA adenosine deaminase
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADM2 adrenomedullin 2
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGXT2 alanine--glyoxylate aminotransferase 2
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMPD1 adenosine monophosphate deaminase 1
APOA1 apolipoprotein A-I
AQP2 aquaporin 2 (collecting duct)
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BRS3 bombesin-like receptor 3
BSG basigin (Ok blood group)
CALCR calcitonin receptor
CALR calreticulin
CASP8AP2 caspase 8 associated protein 2
CASR calcium-sensing receptor
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD34 CD34 molecule
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHGA chromogranin A
CHRM3 cholinergic receptor, muscarinic 3
CLU clusterin
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CRYGC crystallin, gamma C
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCD dermcidin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAAF1 dynein, axonemal, assembly factor 1
DNAH8 dynein, axonemal, heavy chain 8
DPP4 dipeptidyl-peptidase 4
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
FGF23 fibroblast growth factor 23
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FSTL1 follistatin-like 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GPR17 G protein-coupled receptor 17
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
GRK2 G protein-coupled receptor kinase 2
HAMP hepcidin antimicrobial peptide
HDAC9 histone deacetylase 9
HDC histidine decarboxylase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL11 interleukin 11
IL17A interleukin 17A
IL33 interleukin 33
IL34 interleukin 34
IL37 interleukin 37
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IRS1 insulin receptor substrate 1
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KLF13 Kruppel-like factor 13
LCN2 lipocalin 2
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIMK1 LIM domain kinase 1
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LPAR2 lysophosphatidic acid receptor 2
LRPPRC leucine-rich pentatricopeptide repeat containing
MAK16 MAK16 homolog (S. cerevisiae)
MAPK8 mitogen-activated protein kinase 8
MARCKSL1 MARCKS-like 1
MECP2 methyl CpG binding protein 2
MLKL mixed lineage kinase domain-like
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MOV10L1 Mov10 RISC complex RNA helicase like 1
MPRIP myosin phosphatase Rho interacting protein
MSTN myostatin
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MYOG myogenin (myogenic factor 4)
NANOS2 nanos homolog 2 (Drosophila)
NANS N-acetylneuraminic acid synthase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NPR2 natriuretic peptide receptor 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
NT5C2 5'-nucleotidase, cytosolic II
OPRM1 opioid receptor, mu 1
PENK proenkephalin
PIF1 PIF1 5'-to-3' DNA helicase
PLEKHO1 pleckstrin homology domain containing, family O member 1
PNMT phenylethanolamine N-methyltransferase
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNPLA2 patatin-like phospholipase domain containing 2
POMC proopiomelanocortin
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRIMA1 proline rich membrane anchor 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTBP1 polypyrimidine tract binding protein 1
RALBP1 ralA binding protein 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM20 RNA binding motif protein 20
RBMS3 RNA binding motif, single stranded interacting protein 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RHO rhodopsin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RYR2 ryanodine receptor 2 (cardiac)
S100B S100 calcium binding protein B
SCN10A sodium channel, voltage gated, type X alpha subunit
SFTPB surfactant protein B
SIRT1 sirtuin 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMAD3 SMAD family member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOD2 superoxide dismutase 2, mitochondrial
SRRM2 serine/arginine repetitive matrix 2
SSTR4 somatostatin receptor 4
TBPL1 TBP-like 1
TERF2 telomeric repeat binding factor 2
TGFB1 transforming growth factor, beta 1
TIMP4 TIMP metallopeptidase inhibitor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TRIM55 tripartite motif containing 55
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TSPAN31 tetraspanin 31
TSPO translocator protein (18kDa)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor
XDH xanthine dehydrogenase
ZFP90 ZFP90 zinc finger protein