Chronic Periodontitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0266929
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Genes

264 genes associated with the disease Chronic Periodontitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABHD12B abhydrolase domain containing 12B
ACACA acetyl-CoA carboxylase alpha
ACE angiotensin I converting enzyme
ADAM8 ADAM metallopeptidase domain 8
ADGRE1 adhesion G protein-coupled receptor E1
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AIM2 absent in melanoma 2
AMTN amelotin
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
AZU1 azurocidin 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BEGAIN brain-enriched guanylate kinase-associated
BMP2 bone morphogenetic protein 2
BMS1 BMS1 ribosome biogenesis factor
BPI bactericidal/permeability-increasing protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
CAMP cathelicidin antimicrobial peptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD163 CD163 molecule
CD19 CD19 molecule
CD1A CD1a molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD59 CD59 molecule, complement regulatory protein
CD68 CD68 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDSN corneodesmosin
CLU clusterin
CNOT8 CCR4-NOT transcription complex, subunit 8
COL17A1 collagen, type XVII, alpha 1
COL1A1 collagen, type I, alpha 1
COX2
CP20 Lymphocyte cytosolic protein, molecular weight 20kD
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSD cathepsin D
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DAB2IP DAB2 interacting protein
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB1 defensin, beta 1
DEFB104A defensin, beta 104A
DEFB104B defensin, beta 104B
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DKK1 dickkopf WNT signaling pathway inhibitor 1
EBI3 Epstein-Barr virus induced 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAP fibroblast activation protein, alpha
FBLIM1 filamin binding LIM protein 1
FBXO38 F-box protein 38
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GC group-specific component (vitamin D binding protein)
GCFC2 GC-rich sequence DNA-binding factor 2
GOPC golgi-associated PDZ and coiled-coil motif containing
GPX1 glutathione peroxidase 1
GRN granulin
GTF2H5 general transcription factor IIH, polypeptide 5
HAMP hepcidin antimicrobial peptide
HAP1 huntingtin-associated protein 1
HGD homogentisate 1,2-dioxygenase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGFAC HGF activator
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HMGB1 high mobility group box 1
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL32 interleukin 32
IL33 interleukin 33
IL37 interleukin 37
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGA11 integrin, alpha 11
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KLK3 kallikrein-related peptidase 3
KRT23 keratin 23, type I
LEP leptin
LIN28A lin-28 homolog A (C. elegans)
LRPPRC leucine-rich pentatricopeptide repeat containing
LTA lymphotoxin alpha
LTF lactotransferrin
LXN latexin
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MICB MHC class I polypeptide-related sequence B
MLKL mixed lineage kinase domain-like
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP28 matrix metallopeptidase 28
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MPO myeloperoxidase
MPPED1 metallophosphoesterase domain containing 1
MRGPRX2 MAS-related GPR, member X2
MUC7 mucin 7, secreted
MZB1 marginal zone B and B1 cell-specific protein
NCR2 natural cytotoxicity triggering receptor 2
NDEL1 nudE neurodevelopment protein 1-like 1
NFYA nuclear transcription factor Y, alpha
NIN ninein (GSK3B interacting protein)
NLRC5 NLR family, CARD domain containing 5
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPEPPS aminopeptidase puromycin sensitive
NPY neuropeptide Y
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OSM oncostatin M
PF4 platelet factor 4
PGLYRP1 peptidoglycan recognition protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAG1 pleiomorphic adenoma gene 1
PLG plasminogen
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POPDC2 popeye domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
PYDC2 pyrin domain containing 2
QPCTL glutaminyl-peptide cyclotransferase-like
RBM45 RNA binding motif protein 45
RBP4 retinol binding protein 4, plasma
REN renin
RETN resistin
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
S100A8 S100 calcium binding protein A8
SELE selectin E
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SFTPD surfactant protein D
SIGLEC5 sialic acid binding Ig-like lectin 5
SIRT1 sirtuin 1
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SMC3 structural maintenance of chromosomes 3
SOCS1 suppressor of cytokine signaling 1
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
STS steroid sulfatase (microsomal), isozyme S
TAGLN transgelin
TBX21 T-box 21
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
TGM2 transglutaminase 2
TGM3 transglutaminase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
UBE3D ubiquitin protein ligase E3D
UCN2 urocortin 2
UCN3 urocortin 3
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VTN vitronectin
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WNT5A wingless-type MMTV integration site family, member 5A
ZNF410 zinc finger protein 410
ZNF675 zinc finger protein 675