Chronic Sinusitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A chronic form of sinusitis. (Human Phenotype Ontology, HP_0011109)
External Link https://www.disgenet.org/browser/0/1/0/C0149516
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Genes

200 genes associated with the disease Chronic Sinusitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACKR3 atypical chemokine receptor 3
AHR aryl hydrocarbon receptor
ALOX15 arachidonate 15-lipoxygenase
ANKRD36 ankyrin repeat domain 36
AOAH acyloxyacyl hydrolase (neutrophil)
ARG2 arginase 2
ARMC4 armadillo repeat containing 4
BCL2 B-cell CLL/lymphoma 2
BLNK B-cell linker
BPIFA1 BPI fold containing family A, member 1
C11ORF70 chromosome 11 open reading frame 70
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC103 coiled-coil domain containing 103
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CCDC65 coiled-coil domain containing 65
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCNO cyclin O
CD180 CD180 molecule
CD1C CD1c molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD8A CD8a molecule
CFAP298 cilia and flagella associated protein 298
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
COL17A1 collagen, type XVII, alpha 1
COX2
CRLF2 cytokine receptor-like factor 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST1 cystatin SN
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DMBT1 deleted in malignant brain tumors 1
DNAAF1 dynein, axonemal, assembly factor 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAAF3 dynein, axonemal, assembly factor 3
DNAAF4 dynein axonemal assembly factor 4
DNAAF5 dynein, axonemal, assembly factor 5
DNAH1 dynein, axonemal, heavy chain 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DNAI2 dynein, axonemal, intermediate chain 2
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNAL1 dynein, axonemal, light chain 1
DPP4 dipeptidyl-peptidase 4
DRC1 dynein regulatory complex subunit 1
DSG3 desmoglein 3
DSTN destrin (actin depolymerizing factor)
DUOX1 dual oxidase 1
EBI3 Epstein-Barr virus induced 3
EGFR epidermal growth factor receptor
EGR2 early growth response 2
EREG epiregulin
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
GAS2L2 growth arrest-specific 2 like 2
GAS8 growth arrest-specific 8
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GLCCI1 glucocorticoid induced 1
GSK3B glycogen synthase kinase 3 beta
HAVCR2 hepatitis A virus cellular receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA4 heat shock 70kDa protein 4
HYDIN HYDIN, axonemal central pair apparatus protein
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL16 interleukin 16
IL17A interleukin 17A
IL19 interleukin 19
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL22RA1 interleukin 22 receptor, alpha 1
IL25 interleukin 25
IL33 interleukin 33
IL33R interleukin 33 receptor
IL37 interleukin 37
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL9 interleukin 9
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LRRC56 leucine rich repeat containing 56
LRRC6 leucine rich repeat containing 6
LTA lymphotoxin alpha
LYZ lysozyme
MAPK8 mitogen-activated protein kinase 8
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC8 mucin 8
MYDGF myeloid-derived growth factor
NME8 NME/NM23 family member 8
NOS1 nitric oxide synthase 1 (neuronal)
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ODAD1 outer dynein arm docking complex subunit 1
OFD1 oral-facial-digital syndrome 1
PCDH1 protocadherin 1
PDPN podoplanin
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PGM3 phosphoglucomutase 3
PIH1D3 PIH1 domain containing 3
PLA2G1B phospholipase A2, group IB (pancreas)
PLB1 phospholipase B1
POSTN periostin, osteoblast specific factor
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RPGR retinitis pigmentosa GTPase regulator
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
RUNX2 runt-related transcription factor 2
S100A12 S100 calcium binding protein A12
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB3A2 secretoglobin, family 3A, member 2
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPD surfactant protein D
SIPA1 signal-induced proliferation-associated 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SPAG1 sperm associated antigen 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPP1 secreted phosphoprotein 1
STK36 serine/threonine kinase 36
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAS2R38 taste receptor, type 2, member 38
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP73 tumor protein p73
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSLP thymic stromal lymphopoietin
TTC25 tetratricopeptide repeat domain 25
TWIST1 twist family bHLH transcription factor 1
VEGFA vascular endothelial growth factor A
WDPCP WD repeat containing planar cell polarity effector
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZMYND10 zinc finger, MYND-type containing 10