Chronic Thromboembolic Pulmonary Hypertension Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C2363973
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Genes

66 genes associated with the disease Chronic Thromboembolic Pulmonary Hypertension in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALB albumin
BCL2 B-cell CLL/lymphoma 2
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CD34 CD34 molecule
CD40LG CD40 ligand
CD6 CD6 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CXCL10 chemokine (C-X-C motif) ligand 10
DST dystonin
EDN1 endothelin 1
EPHA2 EPH receptor A2
EXD2 exonuclease 3'-5' domain containing 2
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOXO1 forkhead box O1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HP haptoglobin
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
KDR kinase insert domain receptor
MGP matrix Gla protein
MMP2 matrix metallopeptidase 2
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC6 mucin 6, oligomeric mucus/gel-forming
NCAM1 neural cell adhesion molecule 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAH phenylalanine hydroxylase
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PHAX phosphorylated adaptor for RNA export
PPIA peptidylprolyl isomerase A (cyclophilin A)
PROM1 prominin 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGIS prostaglandin I2 (prostacyclin) synthase
REN renin
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SPP1 secreted phosphoprotein 1
TBX1 T-box 1
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
THBD thrombomodulin
TNF tumor necrosis factor