Cicatrix, Hypertrophic Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0162810
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Genes

156 genes associated with the disease Cicatrix, Hypertrophic in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACTB actin, beta
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA5 annexin A5
ARG1 arginase 1
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BMP7 bone morphogenetic protein 7
BRD4 bromodomain containing 4
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CD1A CD1a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CKAP4 cytoskeleton-associated protein 4
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COX2
COX5A cytochrome c oxidase subunit Va
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPOX coproporphyrinogen oxidase
CSAD cysteine sulfinic acid decarboxylase
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DCN decorin
DDR1 discoidin domain receptor tyrosine kinase 1
DIABLO diablo, IAP-binding mitochondrial protein
EDN1 endothelin 1
EGF epidermal growth factor
EIF6 eukaryotic translation initiation factor 6
ELN elastin
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBP1 fructose-1,6-bisphosphatase 1
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FKBP10 FK506 binding protein 10, 65 kDa
FN1 fibronectin 1
GDF9 growth differentiation factor 9
GEMIN2 gem (nuclear organelle) associated protein 2
GHRL ghrelin/obestatin prepropeptide
HAS1 hyaluronan synthase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HOXB9 homeobox B9
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KRT10 keratin 10, type I
KRT14 keratin 14, type I
LAMA1 laminin, alpha 1
LOX lysyl oxidase
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LUM lumican
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MARK2 MAP/microtubule affinity-regulating kinase 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM4 MDM4, p53 regulator
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MSC musculin
MSH3 mutS homolog 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I2 nuclear receptor subfamily 1, group I, member 2
NREP neuronal regeneration related protein
OSM oncostatin M
PCNA proliferating cell nuclear antigen
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
POMC proopiomelanocortin
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
RAG2 recombination activating gene 2
RPE65 retinal pigment epithelium-specific protein 65kDa
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
SCAF11 SR-related CTD-associated factor 11
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SIRT1 sirtuin 1
SIRT7 sirtuin 7
SLC12A9 solute carrier family 12, member 9
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
TAT tyrosine aminotransferase
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS4 thrombospondin 4
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TP53 tumor protein p53
TP63 tumor protein p63
TPM3 tropomyosin 3
TRADD TNFRSF1A-associated via death domain
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VIM vimentin
WNT4 wingless-type MMTV integration site family, member 4
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2