| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.192146 |
| PLAT | plasminogen activator, tissue | 0.184737 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.144207 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.142824 |
| CD44 | CD44 molecule (Indian blood group) | 0.103815 |
| PODXL | podocalyxin-like | 0.102066 |
| LOX | lysyl oxidase | 0.0745961 |
| GLIS3 | GLIS family zinc finger 3 | 0.0637289 |
| B2M | beta-2-microglobulin | 0.0607714 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0595995 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0571913 |
| SEPTIN9 | septin 9 | 0.054768 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0527072 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0509277 |
| NAV1 | neuron navigator 1 | 0.0465116 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0448172 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0441198 |
| MB21D2 | Mab-21 domain containing 2 | 0.0429986 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0424472 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0419447 |
| EFNA5 | ephrin-A5 | 0.0412413 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0406647 |
| CD59 | CD59 molecule, complement regulatory protein | 0.040233 |
| PRSS23 | protease, serine, 23 | 0.040177 |
| MCL1 | myeloid cell leukemia 1 | 0.0396915 |
| S100A10 | S100 calcium binding protein A10 | 0.0383517 |
| RRM2 | ribonucleotide reductase M2 | 0.03749 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0365419 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0360653 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0353935 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0353546 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0351668 |
| NEK7 | NIMA-related kinase 7 | 0.0342598 |
| ERBIN | erbb2 interacting protein | 0.0340176 |
| MED13L | mediator complex subunit 13-like | 0.0337305 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0315259 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.031463 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312686 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0310966 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0304147 |
| H3-3B | H3.3 histone B | 0.0302206 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0301175 |
| MT1X | metallothionein 1X | 0.0300512 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0299021 |
| ATP13A3 | ATPase type 13A3 | 0.0296892 |
| ASPH | aspartate beta-hydroxylase | 0.0296551 |
| CDK6 | cyclin-dependent kinase 6 | 0.0292063 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0290447 |
| ATL3 | atlastin GTPase 3 | 0.0286756 |
| DNMBP | dynamin binding protein | 0.028028 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.027936 |
| SP3 | Sp3 transcription factor | 0.0275264 |
| LMNA | lamin A/C | 0.0272592 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0272288 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0268377 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0266632 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0264447 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0264067 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0263216 |
| MSN | moesin | 0.0262018 |
| RNF144A | ring finger protein 144A | 0.0255404 |
| SMC4 | structural maintenance of chromosomes 4 | 0.025526 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0250432 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0248576 |
| FSTL1 | follistatin-like 1 | 0.0246609 |
| TENM3 | teneurin transmembrane protein 3 | 0.0245264 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.024285 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0242527 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0241943 |
| TPR | translocated promoter region, nuclear basket protein | 0.0240701 |
| BPTF | bromodomain PHD finger transcription factor | 0.0238123 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0232479 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0232356 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0231005 |
| PLXNA2 | plexin A2 | 0.0230104 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0229026 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0228666 |
| SETD5 | SET domain containing 5 | 0.0228655 |
| CUX1 | cut-like homeobox 1 | 0.0226766 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0225065 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0222134 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0221801 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0218074 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.02172 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0216898 |
| VEGFC | vascular endothelial growth factor C | 0.0216895 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.0214549 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0213402 |
| NCKAP1 | NCK-associated protein 1 | 0.021192 |
| DST | dystonin | 0.0211839 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0210816 |
| CDH13 | cadherin 13 | 0.0209896 |
| RPL23 | ribosomal protein L23 | 0.0205807 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0205572 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0204163 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0203019 |
| COL5A2 | collagen, type V, alpha 2 | 0.0202934 |
| CYTH3 | cytohesin 3 | 0.0202702 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0202169 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.020142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.32886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125769 |
| VIM | vimentin | -0.0985904 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0890783 |
| FN1 | fibronectin 1 | -0.0883151 |
| TMSB10 | thymosin beta 10 | -0.0847461 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0720881 |
| AHNAK | AHNAK nucleoprotein | -0.0709772 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0690608 |
| CANX | calnexin | -0.0623082 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0584379 |
| TPM4 | tropomyosin 4 | -0.0568748 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0535271 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0510613 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0498791 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0490242 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0418142 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0400745 |
| HDLBP | high density lipoprotein binding protein | -0.038976 |
| SUCNR1 | succinate receptor 1 | -0.0376109 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0371469 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0365642 |
| SQSTM1 | sequestosome 1 | -0.0348543 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0345588 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0345574 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0345083 |
| SLC38A1 | solute carrier family 38, member 1 | -0.034153 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338269 |
| PTMA | prothymosin, alpha | -0.0333001 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0331344 |
| VEGFA | vascular endothelial growth factor A | -0.0330301 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0326184 |
| MAP1B | microtubule-associated protein 1B | -0.0319561 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0308739 |
| ANXA2 | annexin A2 | -0.0305521 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0302364 |
| TFRC | transferrin receptor | -0.0298443 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0296936 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0293831 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0291087 |
| RND3 | Rho family GTPase 3 | -0.0287218 |
| LRRC17 | leucine rich repeat containing 17 | -0.0285397 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0285292 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.028339 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0273843 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0271535 |
| MSI2 | musashi RNA-binding protein 2 | -0.0271262 |
| CALR | calreticulin | -0.0269024 |
| INSIG1 | insulin induced gene 1 | -0.0262056 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0261278 |
| RRBP1 | ribosome binding protein 1 | -0.0259642 |
| ENO1 | enolase 1, (alpha) | -0.0259488 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0255212 |
| POTEF | POTE ankyrin domain family, member F | -0.0252058 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0250464 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0242552 |
| CENPF | centromere protein F, 350/400kDa | -0.0240832 |
| HM13 | histocompatibility (minor) 13 | -0.024021 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0239463 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0238689 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0238522 |
| MX2 | MX dynamin-like GTPase 2 | -0.0238084 |
| MMP12 | matrix metallopeptidase 12 | -0.0233403 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0232258 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0230054 |
| EGR1 | early growth response 1 | -0.0228589 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0227602 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0224255 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0222999 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0221782 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0219684 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0219496 |
| SEC24D | SEC24 family member D | -0.0208547 |
| IL7R | interleukin 7 receptor | -0.0201997 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0199113 |
| JUN | jun proto-oncogene | -0.0198756 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0197942 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.019714 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0195469 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0191622 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.019155 |
| NGLY1 | N-glycanase 1 | -0.0188692 |
| ARF4 | ADP-ribosylation factor 4 | -0.018849 |
| KRT81 | keratin 81, type II | -0.0188404 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0187457 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0184351 |
| BSG | basigin (Ok blood group) | -0.0181846 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0180422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0179394 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0178603 |
| NAV2 | neuron navigator 2 | -0.0177203 |
| TRAM2 | translocation associated membrane protein 2 | -0.0176504 |
| DTNA | dystrobrevin, alpha | -0.0176493 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.017629 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0175908 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.017567 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0173077 |
| ARF1 | ADP-ribosylation factor 1 | -0.0171163 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.01705 |
| SLFN5 | schlafen family member 5 | -0.0167571 |
