| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.180874 |
| FAT1 | FAT atypical cadherin 1 | 0.156716 |
| ONECUT3 | one cut homeobox 3 | 0.132862 |
| MYO1E | myosin IE | 0.121735 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.102532 |
| NDRG1 | N-myc downstream regulated 1 | 0.0993832 |
| LMO7 | LIM domain 7 | 0.0987112 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0909231 |
| AREG | amphiregulin | 0.08823 |
| B2M | beta-2-microglobulin | 0.0865415 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0843338 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0833193 |
| H1-0 | H1.0 linker histone | 0.0804431 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0693887 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0659265 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.065319 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0647922 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.06269 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0600855 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0589082 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0570801 |
| MUC13 | mucin 13, cell surface associated | 0.0562062 |
| ASPH | aspartate beta-hydroxylase | 0.0559526 |
| EPCAM | epithelial cell adhesion molecule | 0.0539915 |
| FLNB | filamin B, beta | 0.0524648 |
| PARD3 | par-3 family cell polarity regulator | 0.0521527 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0520581 |
| PLS1 | plastin 1 | 0.0520276 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0512985 |
| EGFR | epidermal growth factor receptor | 0.0505117 |
| NEBL | nebulette | 0.0495798 |
| MYO5B | myosin VB | 0.0495274 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0493043 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0492562 |
| MCL1 | myeloid cell leukemia 1 | 0.0486707 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0474687 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0467069 |
| EXT1 | exostosin glycosyltransferase 1 | 0.04668 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0458392 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0457999 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0453188 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.04486 |
| ABHD2 | abhydrolase domain containing 2 | 0.0439779 |
| UBC | ubiquitin C | 0.0438211 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0429999 |
| RIGI | RNA sensor RIG-I | 0.041705 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0415755 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0408979 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0404487 |
| VEGFA | vascular endothelial growth factor A | 0.0395522 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.039268 |
| RNF217 | ring finger protein 217 | 0.0391924 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0389882 |
| ABHD17C | abhydrolase domain containing 17C | 0.03886 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0386949 |
| EZR | ezrin | 0.038693 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0385239 |
| RREB1 | ras responsive element binding protein 1 | 0.0381057 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0380693 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0378618 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.037654 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0376259 |
| DUSP4 | dual specificity phosphatase 4 | 0.0373192 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0370204 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0369306 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0369258 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0368456 |
| TFF1 | trefoil factor 1 | 0.0367595 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0365098 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0357995 |
| SVIL | supervillin | 0.035307 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0346375 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0345867 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0345547 |
| SEPTIN9 | septin 9 | 0.0345392 |
| USP53 | ubiquitin specific peptidase 53 | 0.0344105 |
| FOXO1 | forkhead box O1 | 0.0341603 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0340512 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0331432 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.032816 |
| PGK1 | phosphoglycerate kinase 1 | 0.0327732 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0319601 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0317607 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0316862 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0310143 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0309184 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0308396 |
| ITGA6 | integrin, alpha 6 | 0.0308004 |
| S100A10 | S100 calcium binding protein A10 | 0.0304491 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0302693 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.030017 |
| LAMB3 | laminin, beta 3 | 0.0298539 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0295636 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.02947 |
| RPS7 | ribosomal protein S7 | 0.0293157 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0292124 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0291763 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0290568 |
| RNF145 | ring finger protein 145 | 0.0289764 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0285523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.168459 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.142788 |
| PTMA | prothymosin, alpha | -0.119471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115521 |
| RPL35A | ribosomal protein L35a | -0.0918363 |
| RPLP1 | ribosomal protein, large, P1 | -0.0867095 |
| NPSR1 | neuropeptide S receptor 1 | -0.0838778 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0724725 |
| GPHN | gephyrin | -0.0607368 |
| VCL | vinculin | -0.0581189 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502605 |
| RPL12 | ribosomal protein L12 | -0.0497673 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0465446 |
| POTEF | POTE ankyrin domain family, member F | -0.0458486 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0457071 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0449796 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0436681 |
| RPL34 | ribosomal protein L34 | -0.0402588 |
| CENPF | centromere protein F, 350/400kDa | -0.0400688 |
| HMGB1 | high mobility group box 1 | -0.0396366 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394925 |
| YBX1 | Y box binding protein 1 | -0.0388462 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0383566 |
| RPL32 | ribosomal protein L32 | -0.0365653 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0365528 |
| INSIG1 | insulin induced gene 1 | -0.0359378 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.034333 |
| EGR1 | early growth response 1 | -0.0324736 |
| TNS4 | tensin 4 | -0.0318036 |
| RPL5 | ribosomal protein L5 | -0.0317263 |
| CBX3 | chromobox homolog 3 | -0.0310266 |
| HMGA1 | high mobility group AT-hook 1 | -0.0307373 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0304945 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0293177 |
| RPL36 | ribosomal protein L36 | -0.0288863 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0285929 |
| RPS6 | ribosomal protein S6 | -0.0285601 |
| PFN1 | profilin 1 | -0.0282713 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0282377 |
| AGR2 | anterior gradient 2 | -0.0277598 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0277447 |
| RPLP0 | ribosomal protein, large, P0 | -0.0275962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.027402 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0266848 |
| MLEC | malectin | -0.0263759 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0254943 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0251061 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0249854 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0246132 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0242527 |
| RPS14 | ribosomal protein S14 | -0.0240218 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0239714 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0239496 |
| TUBB | tubulin, beta class I | -0.0236942 |
| MAP4 | microtubule-associated protein 4 | -0.0236658 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0236081 |
| RPL10A | ribosomal protein L10a | -0.023363 |
| DEK | DEK proto-oncogene | -0.0229478 |
| TXNRD1 | thioredoxin reductase 1 | -0.0228996 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0227132 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0224702 |
| S100A14 | S100 calcium binding protein A14 | -0.0223152 |
| RBM25 | RNA binding motif protein 25 | -0.0219198 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0217635 |
| CENPE | centromere protein E, 312kDa | -0.0214204 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0210697 |
| NFIA | nuclear factor I/A | -0.0209399 |
| TUBA1B | tubulin, alpha 1b | -0.0209291 |
| RPL35 | ribosomal protein L35 | -0.0208696 |
| RRBP1 | ribosome binding protein 1 | -0.020765 |
| HDAC2 | histone deacetylase 2 | -0.0205696 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0201941 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0201197 |
| TES | testin LIM domain protein | -0.0200306 |
| GNAS | GNAS complex locus | -0.0199858 |
| TMEM135 | transmembrane protein 135 | -0.0198696 |
| LSAMP | limbic system-associated membrane protein | -0.0198171 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0195732 |
| MATR3 | matrin 3 | -0.0195559 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0194291 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0193758 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0191028 |
| TPX2 | TPX2, microtubule-associated | -0.0188439 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0188218 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0187469 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0186452 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0186386 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0184711 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0182491 |
| WDR45B | WD repeat domain 45B | -0.0182427 |
| SRP72 | signal recognition particle 72kDa | -0.0182124 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0181564 |
| RPS11 | ribosomal protein S11 | -0.0181251 |
| LYZ | lysozyme | -0.0178999 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0178952 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0178657 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0177252 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0174343 |
| RPS24 | ribosomal protein S24 | -0.0173278 |
