| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.141527 |
| NDRG1 | N-myc downstream regulated 1 | 0.139881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.120317 |
| FTL | ferritin, light polypeptide | 0.10339 |
| MSN | moesin | 0.0982407 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0861977 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0793159 |
| MT2A | metallothionein 2A | 0.0741814 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0740052 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0676647 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0668984 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0661401 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0613287 |
| RCOR1 | REST corepressor 1 | 0.0599212 |
| RBM25 | RNA binding motif protein 25 | 0.0592993 |
| TXNIP | thioredoxin interacting protein | 0.056446 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0530459 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0521932 |
| G0S2 | G0/G1 switch 2 | 0.0517351 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0509234 |
| CCNL1 | cyclin L1 | 0.050834 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.049636 |
| LAMB3 | laminin, beta 3 | 0.0496349 |
| POTEF | POTE ankyrin domain family, member F | 0.0494554 |
| PTK2 | protein tyrosine kinase 2 | 0.0491566 |
| MYO6 | myosin VI | 0.0483207 |
| RPS12 | ribosomal protein S12 | 0.0476712 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0466162 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0458724 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0444265 |
| UBC | ubiquitin C | 0.0425648 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0424719 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0419548 |
| MCL1 | myeloid cell leukemia 1 | 0.0416848 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0414146 |
| CLDN4 | claudin 4 | 0.0409155 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0398207 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0395983 |
| JUP | junction plakoglobin | 0.0391743 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0390006 |
| HLA-B | major histocompatibility complex, class I, B | 0.0376215 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0369082 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0369055 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.036371 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0357507 |
| SETD5 | SET domain containing 5 | 0.0353611 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0345559 |
| ACTG1 | actin gamma 1 | 0.034555 |
| HMGA1 | high mobility group AT-hook 1 | 0.0342397 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0341716 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0337489 |
| PCBP2 | poly(rC) binding protein 2 | 0.0337207 |
| H3-3B | H3.3 histone B | 0.0332833 |
| TMF1 | TATA element modulatory factor 1 | 0.0327129 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0324586 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0319332 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0314136 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0314128 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0311356 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306944 |
| RNF145 | ring finger protein 145 | 0.0305706 |
| FAM3C | family with sequence similarity 3, member C | 0.030472 |
| MYO5B | myosin VB | 0.0304489 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0292485 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0292383 |
| BBX | bobby sox homolog (Drosophila) | 0.029095 |
| ERBIN | erbb2 interacting protein | 0.0283537 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0281104 |
| TMEM165 | transmembrane protein 165 | 0.028072 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0277363 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0275294 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.027525 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0274163 |
| TUBB4B | tubulin, beta 4B class IVb | 0.027399 |
| RASA2 | RAS p21 protein activator 2 | 0.0270778 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0269211 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0266574 |
| PARD3 | par-3 family cell polarity regulator | 0.0266111 |
| TPM3 | tropomyosin 3 | 0.0264605 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0262925 |
| RPL37 | ribosomal protein L37 | 0.0257938 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0256175 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0255676 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.025516 |
| B2M | beta-2-microglobulin | 0.0253723 |
| CSTB | cystatin B (stefin B) | 0.0252684 |
| ITGAV | integrin, alpha V | 0.0250727 |
| RAD51B | RAD51 paralog B | 0.0246739 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.024625 |
| DUSP5 | dual specificity phosphatase 5 | 0.0245832 |
| BCL2L1 | BCL2-like 1 | 0.0244669 |
| RPL9 | ribosomal protein L9 | 0.0243866 |
| BRD2 | bromodomain containing 2 | 0.0241967 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0237909 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0236749 |
| NOTCH2 | notch 2 | 0.0235593 |
| ARRDC3 | arrestin domain containing 3 | 0.0235419 |
| ADM | adrenomedullin | 0.0233489 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0232815 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.023253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.443085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.232367 |
| FN1 | fibronectin 1 | -0.10684 |
| CANX | calnexin | -0.0973972 |
| AHNAK | AHNAK nucleoprotein | -0.0898575 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0734167 |
| RPL34 | ribosomal protein L34 | -0.0695526 |
| TMSB10 | thymosin beta 10 | -0.0686781 |
| RPLP1 | ribosomal protein, large, P1 | -0.0639613 |
| RPL35A | ribosomal protein L35a | -0.0629006 |
| TMSB4X | thymosin beta 4, X-linked | -0.0603826 |
| PTMA | prothymosin, alpha | -0.0594893 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0587668 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0547041 |
| ANXA2 | annexin A2 | -0.0546644 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0543814 |
| HDLBP | high density lipoprotein binding protein | -0.0539851 |
| ARF1 | ADP-ribosylation factor 1 | -0.0529714 |
| TPM4 | tropomyosin 4 | -0.0515106 |
| CCND1 | cyclin D1 | -0.0512981 |
| TKT | transketolase | -0.0507481 |
| SQSTM1 | sequestosome 1 | -0.0472124 |
| GNAS | GNAS complex locus | -0.0466979 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.046676 |
| LMO7 | LIM domain 7 | -0.045607 |
| RPL4 | ribosomal protein L4 | -0.0446415 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0443117 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0442423 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041509 |
| RPL8 | ribosomal protein L8 | -0.0412071 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0389661 |
| TFRC | transferrin receptor | -0.038956 |
| S100A10 | S100 calcium binding protein A10 | -0.0383992 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0378633 |
| TMEM263 | transmembrane protein 263 | -0.0369875 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0352742 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0350979 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0350342 |
| PGK1 | phosphoglycerate kinase 1 | -0.0346619 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0345594 |
| RPS6 | ribosomal protein S6 | -0.0343051 |
| TMEM123 | transmembrane protein 123 | -0.0329374 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0314819 |
| RPL6 | ribosomal protein L6 | -0.0306352 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306076 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0305869 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0294167 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0293358 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0288977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0286008 |
| KRT18 | keratin 18, type I | -0.0283792 |
| ASPH | aspartate beta-hydroxylase | -0.0279503 |
| RPS8 | ribosomal protein S8 | -0.0273259 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0271536 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.027107 |
| PLAU | plasminogen activator, urokinase | -0.0270282 |
| HMGB2 | high mobility group box 2 | -0.0255928 |
| CALU | calumenin | -0.0251886 |
| ENO1 | enolase 1, (alpha) | -0.0248243 |
| RPL38 | ribosomal protein L38 | -0.0247404 |
| HMGB1 | high mobility group box 1 | -0.0247201 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0236126 |
| RPS27A | ribosomal protein S27a | -0.0235491 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0235407 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0230323 |
| RACK1 | receptor for activated C kinase 1 | -0.0230211 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0229924 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0229279 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0228477 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0226879 |
| YBX1 | Y box binding protein 1 | -0.0224386 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0224354 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0224259 |
| ZNF217 | zinc finger protein 217 | -0.0223987 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0221613 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0221118 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.022087 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0220622 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0219433 |
| MAP4 | microtubule-associated protein 4 | -0.0217271 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0217172 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0213598 |
| DSG2 | desmoglein 2 | -0.0208598 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0207121 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0206265 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0203853 |
| STK17A | serine/threonine kinase 17a | -0.0200618 |
| RPL32 | ribosomal protein L32 | -0.0200613 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0199983 |
| PHF3 | PHD finger protein 3 | -0.0199851 |
| IER3 | immediate early response 3 | -0.0199794 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0199346 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0198533 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.019848 |
| VIM | vimentin | -0.0196886 |
| DEK | DEK proto-oncogene | -0.0196082 |
| DSPP | dentin sialophosphoprotein | -0.019599 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0195402 |
| EREG | epiregulin | -0.0193757 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0192285 |
