| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.255347 |
| MT2A | metallothionein 2A | 0.161499 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.134704 |
| TMSB10 | thymosin beta 10 | 0.112152 |
| NDRG1 | N-myc downstream regulated 1 | 0.111137 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.109847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0987228 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0924788 |
| PTMA | prothymosin, alpha | 0.0878034 |
| NF1 | neurofibromin 1 | 0.0858935 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0822533 |
| RPLP1 | ribosomal protein, large, P1 | 0.0744756 |
| VIM | vimentin | 0.0741287 |
| RPS3 | ribosomal protein S3 | 0.0710797 |
| RAD51B | RAD51 paralog B | 0.0699315 |
| RPL23 | ribosomal protein L23 | 0.0666419 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0650583 |
| RPL37A | ribosomal protein L37a | 0.0615387 |
| DTNA | dystrobrevin, alpha | 0.0612199 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0603517 |
| BPTF | bromodomain PHD finger transcription factor | 0.0601408 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.057659 |
| ENO1 | enolase 1, (alpha) | 0.0572726 |
| RPS6 | ribosomal protein S6 | 0.0551363 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0542099 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0540723 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.053578 |
| BRD2 | bromodomain containing 2 | 0.0527937 |
| FN1 | fibronectin 1 | 0.0511843 |
| JUN | jun proto-oncogene | 0.0505542 |
| RUNX1 | runt-related transcription factor 1 | 0.0498835 |
| ASPH | aspartate beta-hydroxylase | 0.0496151 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0485988 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0469975 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0468239 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0458539 |
| EGFR | epidermal growth factor receptor | 0.045638 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0451499 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0442469 |
| EXT1 | exostosin glycosyltransferase 1 | 0.043762 |
| RPL12 | ribosomal protein L12 | 0.0433053 |
| SBF2 | SET binding factor 2 | 0.0428503 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0417308 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0413662 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0410485 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0407304 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0351301 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0343343 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0342154 |
| VMP1 | vacuole membrane protein 1 | 0.0331658 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0329938 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0325176 |
| RTN4 | reticulon 4 | 0.0323082 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0308813 |
| PGK1 | phosphoglycerate kinase 1 | 0.0307125 |
| AHNAK | AHNAK nucleoprotein | 0.0298442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0289963 |
| FBXO11 | F-box protein 11 | 0.0286888 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0282118 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0278513 |
| RPL37 | ribosomal protein L37 | 0.0276574 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0274963 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266984 |
| PCBP2 | poly(rC) binding protein 2 | 0.0261915 |
| EZR | ezrin | 0.0259256 |
| MYO1E | myosin IE | 0.02589 |
| SYT1 | synaptotagmin I | 0.0237982 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0227745 |
| MCL1 | myeloid cell leukemia 1 | 0.0223109 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0222902 |
| RPL19 | ribosomal protein L19 | 0.0211188 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0205741 |
| APP | amyloid beta (A4) precursor protein | 0.0201229 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0192081 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0186794 |
| SON | SON DNA binding protein | 0.0173631 |
| ERBIN | erbb2 interacting protein | 0.0166085 |
| SMAD3 | SMAD family member 3 | 0.0164229 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0157367 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0140629 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0133037 |
| ZNF292 | zinc finger protein 292 | 0.0129758 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0125471 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.012493 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0117178 |
| MEF2A | myocyte enhancer factor 2A | 0.0111544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0107366 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0107298 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0106616 |
| FLNB | filamin B, beta | 0.00987898 |
| B2M | beta-2-microglobulin | 0.00981906 |
| SLTM | SAFB-like, transcription modulator | 0.00936754 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0086932 |
| PRELID2 | PRELI domain containing 2 | 0.00781 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00776976 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00641994 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00640864 |
| PRKCA | protein kinase C, alpha | 0.00434557 |
| TPR | translocated promoter region, nuclear basket protein | 0.00396828 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00294723 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.139787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110047 |
| HDLBP | high density lipoprotein binding protein | -0.107957 |
| FAM13A | family with sequence similarity 13, member A | -0.107157 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.091322 |
| GPC6 | glypican 6 | -0.089256 |
| TFG | TRK-fused gene | -0.0838822 |
| GPHN | gephyrin | -0.080919 |
| LYST | lysosomal trafficking regulator | -0.0799977 |
| PDE10A | phosphodiesterase 10A | -0.0774229 |
| VCL | vinculin | -0.0747557 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0733892 |
| GOLGA4 | golgin A4 | -0.0718407 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0714274 |
| POTEF | POTE ankyrin domain family, member F | -0.0713374 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0709051 |
| PDE8A | phosphodiesterase 8A | -0.0703896 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0694786 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0694599 |
| CALD1 | caldesmon 1 | -0.0691657 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0674143 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0670406 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0654539 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.064679 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0638911 |
| ANXA2 | annexin A2 | -0.0624588 |
| TJP1 | tight junction protein 1 | -0.0620797 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.060135 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0584468 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0577058 |
| FAT1 | FAT atypical cadherin 1 | -0.055568 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.055302 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0546674 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0536529 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0532353 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0515408 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0508807 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0507876 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0500194 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0499409 |
| STC1 | stanniocalcin 1 | -0.0489903 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0476749 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0476719 |
| RPS16 | ribosomal protein S16 | -0.047657 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0470944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0453935 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0451069 |
| INHBA | inhibin, beta A | -0.0450153 |
| RPL35A | ribosomal protein L35a | -0.043985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438725 |
| CANX | calnexin | -0.0433831 |
| FOXP1 | forkhead box P1 | -0.0433631 |
| FMNL2 | formin-like 2 | -0.0432887 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0423763 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0413748 |
| JMJD1C | jumonji domain containing 1C | -0.0410032 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0407025 |
| DSPP | dentin sialophosphoprotein | -0.0406862 |
| SPAG9 | sperm associated antigen 9 | -0.0404109 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0402856 |
| FTL | ferritin, light polypeptide | -0.0397501 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0391149 |
| LMO7 | LIM domain 7 | -0.038742 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0387184 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0371231 |
| S100A10 | S100 calcium binding protein A10 | -0.0359132 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0358308 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0357939 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.035305 |
| ITGA6 | integrin, alpha 6 | -0.0347667 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0343204 |
| CDK6 | cyclin-dependent kinase 6 | -0.0309006 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0295318 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0286015 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0283057 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0276117 |
| IGF2 | insulin-like growth factor 2 | -0.0270926 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0269078 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0267339 |
| HMGA2 | high mobility group AT-hook 2 | -0.0254559 |
| PKM | pyruvate kinase, muscle | -0.0254552 |
| CCNI | cyclin I | -0.0254235 |
| OGA | O-GlcNAcase | -0.025376 |
| SQSTM1 | sequestosome 1 | -0.0238192 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0222015 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0218694 |
| RBM39 | RNA binding motif protein 39 | -0.0212978 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0212365 |
| MYO10 | myosin X | -0.0211797 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0204551 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0191278 |
| USP34 | ubiquitin specific peptidase 34 | -0.0186975 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0176994 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0172853 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0168888 |
| SEPTIN9 | septin 9 | -0.0165353 |
| H3-3B | H3.3 histone B | -0.0161608 |
| DST | dystonin | -0.0143616 |
| SMYD3 | SET and MYND domain containing 3 | -0.0137389 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.013245 |
