| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.192709 |
| COL5A2 | collagen, type V, alpha 2 | 0.128579 |
| PEG10 | paternally expressed 10 | 0.125988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.125222 |
| CADM2 | cell adhesion molecule 2 | 0.111027 |
| GPC3 | glypican 3 | 0.11101 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.102807 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0962993 |
| VIM | vimentin | 0.0952943 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.094547 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0812636 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0629264 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0607691 |
| TENM3 | teneurin transmembrane protein 3 | 0.0545612 |
| RPL23 | ribosomal protein L23 | 0.053929 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0537618 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0537102 |
| H1-0 | H1.0 linker histone | 0.0524098 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.049413 |
| ANXA1 | annexin A1 | 0.0491643 |
| METAP2 | methionyl aminopeptidase 2 | 0.0489592 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0473522 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0473027 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.046609 |
| ACTG1 | actin gamma 1 | 0.0454449 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0444239 |
| ITGAV | integrin, alpha V | 0.0444082 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0437458 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0435421 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0426686 |
| RPS16 | ribosomal protein S16 | 0.0417245 |
| PGK1 | phosphoglycerate kinase 1 | 0.041646 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0414134 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.039266 |
| RPL7 | ribosomal protein L7 | 0.0389974 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0380151 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0374549 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0372991 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0371775 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0369673 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0367561 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0360254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0346355 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0340713 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0340593 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0338622 |
| RACK1 | receptor for activated C kinase 1 | 0.033777 |
| PCDH18 | protocadherin 18 | 0.0331817 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0331628 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0326785 |
| COL1A2 | collagen, type I, alpha 2 | 0.0324417 |
| THBS1 | thrombospondin 1 | 0.0323759 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0316212 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316102 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03113 |
| COL3A1 | collagen, type III, alpha 1 | 0.0309871 |
| B2M | beta-2-microglobulin | 0.030744 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300062 |
| SHROOM3 | shroom family member 3 | 0.0296477 |
| SRPK2 | SRSF protein kinase 2 | 0.0295388 |
| CDK6 | cyclin-dependent kinase 6 | 0.0294403 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0289234 |
| MEF2C | myocyte enhancer factor 2C | 0.0285323 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0283216 |
| PCDH9 | protocadherin 9 | 0.0282032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0278822 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.0278186 |
| RAI1 | retinoic acid induced 1 | 0.0277656 |
| DENND4A | DENN/MADD domain containing 4A | 0.0277649 |
| KHSRP | KH-type splicing regulatory protein | 0.027133 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.027021 |
| SFRP4 | secreted frizzled-related protein 4 | 0.027 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0268167 |
| RPL11 | ribosomal protein L11 | 0.0265571 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.026485 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0263639 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026306 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0261982 |
| MYO10 | myosin X | 0.025973 |
| RPL5 | ribosomal protein L5 | 0.0257375 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0256722 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0256022 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0255295 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0254849 |
| CLTC | clathrin, heavy chain (Hc) | 0.0252134 |
| FOXG1 | forkhead box G1 | 0.0251818 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | 0.0250294 |
| DST | dystonin | 0.0248817 |
| PHF6 | PHD finger protein 6 | 0.024868 |
| NONO | non-POU domain containing, octamer-binding | 0.0246493 |
| REST | RE1-silencing transcription factor | 0.0243402 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0242493 |
| SETD5 | SET domain containing 5 | 0.0242012 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0240285 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0237509 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0236659 |
| RTN4 | reticulon 4 | 0.0236482 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0234027 |
| SSRP1 | structure specific recognition protein 1 | 0.0231517 |
| RPL19 | ribosomal protein L19 | 0.023032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109432 |
| TMSB10 | thymosin beta 10 | -0.0503476 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0503324 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0478599 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472502 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0469821 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0453071 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0444638 |
| ZNF638 | zinc finger protein 638 | -0.0405108 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.040233 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0367691 |
| INTS6 | integrator complex subunit 6 | -0.036588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035102 |
| SQSTM1 | sequestosome 1 | -0.0348731 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0343828 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0337797 |
| RPL35A | ribosomal protein L35a | -0.0333731 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0331194 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0324851 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0322158 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313309 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0311077 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0307273 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0306151 |
| RLF | rearranged L-myc fusion | -0.0299475 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0294744 |
| FOXP2 | forkhead box P2 | -0.0285238 |
| PLPP1 | phospholipid phosphatase 1 | -0.0283932 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0278087 |
| HMGB1 | high mobility group box 1 | -0.0270855 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0270393 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0267946 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0263327 |
| PTMA | prothymosin, alpha | -0.0263142 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.026027 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0259655 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258758 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0255326 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253347 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0251083 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0249064 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0247687 |
| MORF4L2 | mortality factor 4 like 2 | -0.0247047 |
| NTM | neurotrimin | -0.024616 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0244515 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0240877 |
| OGA | O-GlcNAcase | -0.0239516 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.023826 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0237587 |
| FOXO1 | forkhead box O1 | -0.0234166 |
| TMEM87A | transmembrane protein 87A | -0.0233511 |
| CCN2 | cellular communication network factor 2 | -0.0232794 |
| COPA | coatomer protein complex, subunit alpha | -0.023088 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0226839 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0226794 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0225785 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0222793 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0221291 |
| FTL | ferritin, light polypeptide | -0.0219479 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0219311 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0219211 |
| MPG | N-methylpurine-DNA glycosylase | -0.0216952 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | -0.0216642 |
| NHSL1 | NHS-like 1 | -0.0216309 |
| PRR16 | proline rich 16 | -0.0214973 |
| REEP3 | receptor accessory protein 3 | -0.0210539 |
| ZNF217 | zinc finger protein 217 | -0.020999 |
| SERTAD1 | SERTA domain containing 1 | -0.0206054 |
| FST | follistatin | -0.0205808 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | -0.02037 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0203677 |
| PRKCA | protein kinase C, alpha | -0.019929 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0199139 |
| NXN | nucleoredoxin | -0.0198433 |
| PCNX1 | pecanex 1 | -0.0198082 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0197513 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0195164 |
| RBM39 | RNA binding motif protein 39 | -0.0195057 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0194347 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0193944 |
| TCF20 | transcription factor 20 (AR1) | -0.0193352 |
| ANK2 | ankyrin 2, neuronal | -0.019207 |
| USP53 | ubiquitin specific peptidase 53 | -0.0191416 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0190895 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0190152 |
| RPL36A | ribosomal protein L36a | -0.0189884 |
| VCL | vinculin | -0.0189123 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0188402 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0188332 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0188266 |
| CDH19 | cadherin 19, type 2 | -0.0185909 |
| RASAL2 | RAS protein activator like 2 | -0.0185847 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0185598 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0185445 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0184801 |
| UBE2Q2 | ubiquitin-conjugating enzyme E2Q family member 2 | -0.0184688 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0183926 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0183816 |
| SCAI | suppressor of cancer cell invasion | -0.0183421 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0183233 |
