| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.144111 |
| COL6A3 | collagen, type VI, alpha 3 | 0.142886 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.1276 |
| GLIS3 | GLIS family zinc finger 3 | 0.121776 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.121349 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0946518 |
| FN1 | fibronectin 1 | 0.076112 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0714076 |
| PDE10A | phosphodiesterase 10A | 0.0685135 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0644775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0636302 |
| KYNU | kynureninase | 0.061297 |
| HMGA2 | high mobility group AT-hook 2 | 0.061118 |
| CD44 | CD44 molecule (Indian blood group) | 0.0608887 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0600789 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0597498 |
| VCAN | versican | 0.0588793 |
| PGK1 | phosphoglycerate kinase 1 | 0.0560259 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0555838 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0538647 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0528016 |
| SFTPA2 | surfactant protein A2 | 0.0506703 |
| HDAC9 | histone deacetylase 9 | 0.050276 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0480445 |
| GPC6 | glypican 6 | 0.0474938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0473357 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0466767 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0462344 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.045863 |
| BICC1 | BicC family RNA binding protein 1 | 0.0454298 |
| NDRG1 | N-myc downstream regulated 1 | 0.0444566 |
| COL5A1 | collagen, type V, alpha 1 | 0.0443312 |
| INHBA | inhibin, beta A | 0.0440829 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0429594 |
| STC1 | stanniocalcin 1 | 0.0429111 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0416976 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0412007 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0395263 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0382064 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0379601 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0378861 |
| ASPH | aspartate beta-hydroxylase | 0.0374044 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0365018 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0362103 |
| LDHA | lactate dehydrogenase A | 0.0361366 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0357781 |
| ATXN1 | ataxin 1 | 0.0352389 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0344677 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0327781 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0327732 |
| SEPTIN9 | septin 9 | 0.0326236 |
| LOX | lysyl oxidase | 0.0322501 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032022 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0315338 |
| RND3 | Rho family GTPase 3 | 0.0313033 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0311613 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0308969 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0308141 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0305779 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.030489 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0303378 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0303165 |
| NAV1 | neuron navigator 1 | 0.030171 |
| HLA-A | major histocompatibility complex, class I, A | 0.0298596 |
| INTS6 | integrator complex subunit 6 | 0.0298094 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0297233 |
| DST | dystonin | 0.029317 |
| SMYD3 | SET and MYND domain containing 3 | 0.0286603 |
| RPL11 | ribosomal protein L11 | 0.0286116 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.028553 |
| EGFR | epidermal growth factor receptor | 0.028465 |
| EHBP1 | EH domain binding protein 1 | 0.0281224 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0280891 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0272923 |
| JMJD1C | jumonji domain containing 1C | 0.0265888 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0258882 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0255817 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0251924 |
| MSN | moesin | 0.0248009 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0246579 |
| RPL7A | ribosomal protein L7a | 0.0245725 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0245609 |
| RPS21 | ribosomal protein S21 | 0.0242382 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0242014 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0241916 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0238898 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0233836 |
| PTK2 | protein tyrosine kinase 2 | 0.0233125 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.023084 |
| TNS3 | tensin 3 | 0.0230773 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0227172 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0226836 |
| B2M | beta-2-microglobulin | 0.0226801 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0226435 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0225904 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0223987 |
| FRMD4A | FERM domain containing 4A | 0.0223316 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0222988 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0221077 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0219682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.134524 |
| VIM | vimentin | -0.103252 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.075853 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0667847 |
| TMSB10 | thymosin beta 10 | -0.0641987 |
| UBC | ubiquitin C | -0.057626 |
| PCBP2 | poly(rC) binding protein 2 | -0.056039 |
| RPS27A | ribosomal protein S27a | -0.0560378 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0517292 |
| PTMA | prothymosin, alpha | -0.0500597 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0481063 |
| ENO1 | enolase 1, (alpha) | -0.0422785 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0414447 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0410596 |
| CANX | calnexin | -0.039766 |
| TPM4 | tropomyosin 4 | -0.038528 |
| AHNAK | AHNAK nucleoprotein | -0.0381898 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.038046 |
| RTN4 | reticulon 4 | -0.0361846 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0356869 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0346875 |
| THBS1 | thrombospondin 1 | -0.032746 |
| MX1 | MX dynamin-like GTPase 1 | -0.0325435 |
| CENPF | centromere protein F, 350/400kDa | -0.0324431 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.030723 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0306034 |
| ARRDC3 | arrestin domain containing 3 | -0.0303863 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.028634 |
| APP | amyloid beta (A4) precursor protein | -0.0280306 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0277261 |
| ARF4 | ADP-ribosylation factor 4 | -0.0275769 |
| RPS3 | ribosomal protein S3 | -0.027364 |
| POTEF | POTE ankyrin domain family, member F | -0.0269345 |
| TPM1 | tropomyosin 1 (alpha) | -0.0257325 |
| FLNA | filamin A, alpha | -0.0253646 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0244744 |
| TXNRD1 | thioredoxin reductase 1 | -0.0244337 |
| NAV2 | neuron navigator 2 | -0.0242727 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0242513 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0234612 |
| RPLP1 | ribosomal protein, large, P1 | -0.0231716 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0227652 |
| ZNF292 | zinc finger protein 292 | -0.022588 |
| MATR3 | matrin 3 | -0.0224055 |
| CALU | calumenin | -0.0223288 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0220422 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0212311 |
| PKM | pyruvate kinase, muscle | -0.0210697 |
| ANXA2 | annexin A2 | -0.0210273 |
| HMGB2 | high mobility group box 2 | -0.0209946 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0206669 |
| JUN | jun proto-oncogene | -0.0203495 |
| ANLN | anillin, actin binding protein | -0.0202857 |
| TPX2 | TPX2, microtubule-associated | -0.0198689 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0195271 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0191754 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0191339 |
| C3 | complement component 3 | -0.0191069 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0190942 |
| YBX1 | Y box binding protein 1 | -0.0189507 |
| COL1A1 | collagen, type I, alpha 1 | -0.0185895 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0180842 |
| EGR1 | early growth response 1 | -0.0179767 |
| KIF4A | kinesin family member 4A | -0.0178869 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0177765 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0176701 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0176548 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0176449 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0174205 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0173408 |
| FOSL1 | FOS-like antigen 1 | -0.0172704 |
| RPL35A | ribosomal protein L35a | -0.0165603 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.016315 |
| RHOA | ras homolog family member A | -0.0162947 |
| SQSTM1 | sequestosome 1 | -0.0162884 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0162465 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0162328 |
| SDC4 | syndecan 4 | -0.0161536 |
| PRKD3 | protein kinase D3 | -0.0160899 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0159389 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0159137 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0155078 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0154898 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0152669 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0149698 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0149643 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0147367 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0146371 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0145321 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.014436 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0142718 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0142553 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0141815 |
| HLA-E | major histocompatibility complex, class I, E | -0.0140943 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0140762 |
| GOLGA4 | golgin A4 | -0.0134713 |
| TKT | transketolase | -0.0133898 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0131993 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0129504 |
| TMEM41B | transmembrane protein 41B | -0.0129311 |
